Investors who own more than 5% of a class must file a Schedule 13D or 13G. Each filer's latest filing for 86889P208 since 12/18/2024, largest first.
| Filer | % of Class | Filed | ||
|---|---|---|---|---|
|
Column Group III GP, LP
13D/A
|
29.3% |
5/18/2026
Event 3/31/2026
|
||
| The Column Group III GP, LP | 23.6% | |||
| The Column Group III, LP | 11.6% | |||
| The Column Group III-A, LP | 13.0% | |||
| The Column Group Opportunity III, LP | 7.2% | |||
| The Column Group Opportunity III GP, LP | 7.2% | |||
| TCG Opportunity III GP, LLC | 7.2% | |||
| Tim Kutzkey | 29.3% | |||
| Peter Svennilson | 29.3% | |||
|
Column Group IV GP, LP
13D
|
11.6% |
2/12/2026
Event 2/6/2026
|
||
| The Column Group IV GP, LP | 8.3% | |||
| The Column Group IV, LP | 8.0% | |||
| The Column Group IV-A, LP | 0.3% | |||
| The Column Group Opportunity III, LP | 3.5% | |||
| The Column Group Opportunity III GP, LP | 3.5% | |||
| TCG Opportunity III GP, LLC | 3.5% | |||
| Tim Kutzkey | 11.6% | |||
| Peter Svennilson | 11.6% | |||
|
Boxer Capital Management, LLC
13G/A
|
11.6% |
10/7/2026
Event 9/30/2026
|
||
| Boxer Capital Management, LLC | 11.6% | |||
| Boxer Holdings, LP | 11.6% | |||
| Boxer Holdings GP, LLC | 11.6% | |||
| Aaron Davis | 11.6% | |||
|
Venrock Healthcare Capital Partners III, L.P.
13G/A
|
9.9% |
5/15/2026
Event 3/31/2026
|
||
| Venrock Healthcare Capital Partners III, L.P. | 9.9% | |||
| VHCP Co-Investment Holdings III, LLC | 9.9% | |||
| Venrock Healthcare Capital Partners EG, L.P. | 9.9% | |||
| VHCP Management III, LLC | 9.9% | |||
| VHCP Management EG, LLC | 9.9% | |||
| Nimish Shah | 9.9% | |||
| Bong Y. Koh | 9.9% | |||
|
TCG Crossover GP II, LLC
13G/A
|
9.9% |
7/24/2026
Event 7/22/2026
|
||
| TCG Crossover GP II, LLC | 4.9% | |||
| TCG Crossover Fund II, L.P. | 4.9% | |||
| TCG Crossover GP III, LLC | 4.9% | |||
| TCG Crossover Fund III, L.P. | 4.9% | |||
| Chen Yu | 9.9% | |||
|
AI Biotechnology LLC
13G
|
9.9% |
3/31/2025
Event 3/24/2025
|
||
| AI Biotechnology LLC | 9.9% | |||
| Access Industries Holdings LLC | 9.9% | |||
| Access Industries Management, LLC | 9.9% | |||
| Len Blavatnik | 9.9% | |||
|
RA Capital Management, L.P.
13G/A
|
9.2% |
2/17/2026
Event 12/31/2025
|
||
| RA Capital Management, L.P. | 9.2% | |||
| Peter Kolchinsky | 9.2% | |||
| Rajeev Shah | 9.2% | |||
| RA Capital Healthcare Fund, L.P. | 9.2% | |||
|
Integrated Core Strategies (US) LLC
13G/A
|
8.5% |
2/5/2026
Event 12/31/2025
|
||
| Integrated Core Strategies (US) LLC | 8.4% | |||
| Millennium Management LLC | 8.5% | |||
| Millennium Group Management LLC | 8.5% | |||
| Israel A. Englander | 8.5% | |||
|
5AM Partners VII, LLC
13G/A
|
7.8% |
8/11/2026
Event 6/30/2026
|
||
| 5AM Partners VII, LLC | 7.8% | |||
| 5AM Ventures VII, L.P. | 7.8% | |||
| Kush Parmar | 7.8% | |||
| Andrew J. Schwab | 7.8% | |||
|
Commodore Capital LP
13G
|
7.5% |
10/1/2026
Event 9/24/2026
|
||
| Commodore Capital LP | 7.5% | |||
| Commodore Capital Master LP | 7.5% | |||
| Robert Egen Atkinson | 7.5% | |||
| Michael Kramarz | 7.5% | |||
|
Point72 Asset Management, L.P.
13G
|
5.4% |
4/23/2026
Event 4/22/2026
|
||
| Point72 Asset Management, L.P. | 5.4% | |||
| Point72 Capital Advisors, Inc. | 5.4% | |||
| Steven A. Cohen | 5.4% | |||
|
StemPoint Capital LP
13G
|
5.0% |
8/14/2026
Event 6/30/2026
|
||
| StemPoint Capital LP | 5.0% | |||
| StemPoint Capital Management GP LLC | 5.0% | |||
| Michelle Ross | 5.0% | |||
| Under 5%, checked the "5 percent or less" box, or amended by a later filing (8) | ||||
| Regents of the University of California 13G | 4.2% |
1/28/2025
Event 12/31/2024
|
||
|
Braidwell LP
13G/A
|
3.9% |
8/14/2026
Event 6/30/2026
|
||
| Braidwell LP | 3.9% | |||
| Braidwell Management LLC | 3.9% | |||
| Alexander T. Karnal | 3.9% | |||
| Brian J. Kreiter | 3.9% | |||
|
Stonepine Capital Management, LLC
13G/A
|
3.6% |
2/13/2026
Event 12/31/2025
|
||
| Stonepine Capital Management, LLC | 3.6% | |||
| Stonepine Capital, L.P. | 3.6% | |||
| Stonepine GP, LLC | 3.6% | |||
| Jon M. Plexico | 3.6% | |||
| Nantahala Capital Partners Limited Partnership 13G/A | 2.2% |
5/15/2025
Event 3/31/2025
|
||
|
Nantahala Capital Management, LLC
13G/A
|
2.1% |
5/15/2026
Event 3/31/2026
|
||
| Nantahala Capital Management, LLC | 2.1% | |||
| Wilmot B. Harkey | 2.1% | |||
| Daniel Mack | 2.1% | |||
|
Perceptive Advisors LLC
13G/A
|
1.9% |
5/15/2025
Event 3/31/2025
|
||
| Perceptive Advisors LLC | 1.9% | |||
| Joseph Edelman | 1.9% | |||
| Perceptive Life Sciences Master Fund, Ltd. | 1.9% | |||
|
Alyeska Investment Group, L.P.
13G/A
|
0.8% |
2/14/2025
Event 12/31/2024
|
||
| Alyeska Investment Group, L.P. | 0.8% | |||
| Alyeska Fund GP, LLC | 0.8% | |||
| Anand Parekh | 0.8% | |||
| Driehaus Capital Management LLC 13G/A | 0.8% |
8/14/2025
Event 6/30/2025
|
||
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 1 | 62.0 | $2.00 k |
| 2026 Q2 | 71 | 10.7 M | $275 M |
| 2026 Q1 | 60 | 9.51 M | $275 M |
| 2025 Q4 | 55 | 7.27 M | $156 M |
| 2025 Q3 | 36 | 4.98 M | $64.1 M |
| 2025 Q2 | 32 | 4.66 M | $41.7 M |
| 2025 Q1 | 30 | 3.95 M | $46.0 M |
| 2024 Q4 | 24 | 1.66 M | $23.8 M |
| 2024 Q3 | 24 | 1.32 M | $15.8 M |
| 2024 Q2 | 25 | 1.52 M | $16.6 M |
| 2024 Q1 | 19 | 411 k | $6.42 M |
| 2023 Q4 | 20 | 448 k | $4.21 M |