Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 78397T202 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Commodore Capital LP
13G/A
Amendment 1
|
9.9% |
8/14/2026
Event 6/30/2026
|
|
| Commodore Capital LP | 9.9% | ||
| Commodore Capital Master LP | 9.9% | ||
| Robert Egen Atkinson | 9.9% | ||
| Michael Kramarz | 9.9% | ||
|
Caligan Partners LP
13G/A
Amendment 1
|
8.8% |
8/14/2026
Event 6/30/2026
|
|
| Caligan Partners LP | 8.8% | ||
| Johnson David Edward | 8.8% | ||
|
Vivo Opportunity Fund Holdings, L.P.
13G/A
Amendment 1
|
10.0% |
8/14/2026
Event 6/30/2026
|
|
| Vivo Opportunity Fund Holdings, L.P. | 10.0% | ||
| Vivo Opportunity, LLC | 10.0% | ||
| Vivo Opportunity Cayman Fund, L.P. | 10.0% | ||
| Vivo Opportunity Cayman, LLC | 10.0% | ||
|
Perceptive Advisors LLC
13G/A
Amendment 2
|
7.3% |
8/14/2026
Event 6/30/2026
|
|
| Perceptive Advisors LLC | 7.3% | ||
| Joseph Edelman | 7.3% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 7.3% | ||
|
Balyasny Asset Management L.P.
13G/A
Amendment 1
|
9.5% |
8/14/2026
Event 6/30/2026
|
|
| Balyasny Asset Management L.P. | 9.5% | ||
| Bam GP LLC | 9.5% | ||
| Balyasny Asset Management Holdings LP | 9.5% | ||
| Dames GP LLC | 9.5% | ||
| Dmitry Balyasny | 9.5% | ||
| Woodline Partners LP 13G/A Amendment 1 | 6.8% |
8/14/2026
Event 6/30/2026
|
|
|
Adage Capital Management, L.P.
13G
|
8.4% |
8/12/2026
Event 6/30/2026
|
|
| Adage Capital Management, L.P. | 8.4% | ||
| Robert Atchinson | 8.4% | ||
| Phillip Gross | 8.4% | ||
|
RA Capital Management, L.P.
13D/A
Amendment 3
|
9.9% |
8/10/2026
Event 8/6/2026
|
|
| RA Capital Management, L.P. | 9.9% | ||
| Peter Kolchinsky | 9.9% | ||
| Rajeev Shah | 9.9% | ||
| RA Capital Healthcare Fund, L.P. | 9.9% | ||
|
Caligan Partners LP
13G
|
10.4% |
5/15/2026
Event 3/31/2026
|
|
| Caligan Partners LP | 10.4% | ||
| Johnson David Edward | 10.4% | ||
|
Perceptive Advisors LLC
13G/A
Amendment 1
|
8.4% |
5/15/2026
Event 3/31/2026
|
|
| Perceptive Advisors LLC | 8.4% | ||
| Joseph Edelman | 8.4% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 8.4% | ||
|
Balyasny Asset Management L.P.
13G
|
10.0% |
5/15/2026
Event 3/31/2026
|
|
| Balyasny Asset Management L.P. | 10.0% | ||
| Bam GP LLC | 10.0% | ||
| Balyasny Asset Management Holdings LP | 10.0% | ||
| Dames GP LLC | 10.0% | ||
| Dmitry Balyasny | 10.0% | ||
|
Millennium Management LLC
13G
|
5.1% |
5/1/2026
Event 4/24/2026
|
|
| Millennium Management LLC | 5.1% | ||
| Millennium Group Management LLC | 5.1% | ||
| Israel A. Englander | 5.1% | ||
|
RA Capital Management, L.P.
13D/A
Amendment 2
|
9.9% |
3/23/2026
Event 3/19/2026
|
|
| RA Capital Management, L.P. | 9.9% | ||
| Peter Kolchinsky | 9.9% | ||
| Rajeev Shah | 9.9% | ||
| RA Capital Healthcare Fund, L.P. | 9.9% | ||
|
RA Capital Management, L.P.
13D/A
Amendment 1
|
9.9% |
3/11/2026
Event 3/9/2026
|
|
| RA Capital Management, L.P. | 9.9% | ||
| Peter Kolchinsky | 9.9% | ||
| Rajeev Shah | 9.9% | ||
| RA Capital Healthcare Fund, L.P. | 9.9% | ||
|
RTW Investments, LP
13G/A
Amendment 2
|
3.2% |
2/17/2026
Event 12/31/2025
|
|
| RTW Investments, LP | 3.2% | ||
| Roderick Wong | 3.2% | ||
|
Biotechnology Value Fund L P
13G/A
Amendment 2
|
9.1% |
2/17/2026
Event 12/31/2025
|
|
| Biotechnology Value Fund L P | 5.1% | ||
| BVF I GP LLC | 5.1% | ||
| Biotechnology Value Fund II LP | 3.9% | ||
| BVF II GP LLC | 3.9% | ||
| Biotechnology Value Trading Fund OS LP | 0.5% | ||
| BVF Partners OS Ltd. | 0.5% | ||
| BVF GP Holdings LLC | 8.6% | ||
| BVF Partners L P/IL | 9.1% | ||
| BVF Inc/IL | 9.1% | ||
| Lampert Mark N | 9.1% | ||
|
Perceptive Advisors LLC
13G
|
7.3% |
1/22/2026
Event 1/14/2026
|
|
| Perceptive Advisors LLC | 7.3% | ||
| Joseph Edelman | 7.3% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 7.3% | ||
|
Biotechnology Value Fund L P
13G/A
Amendment 1
|
10.0% |
11/14/2025
Event 9/30/2025
|
|
| Biotechnology Value Fund L P | 6.1% | ||
| BVF I GP LLC | 6.1% | ||
| Biotechnology Value Fund II LP | 4.2% | ||
| BVF II GP LLC | 4.2% | ||
| Biotechnology Value Trading Fund OS LP | 0.1% | ||
| BVF Partners OS Ltd. | 0.1% | ||
| BVF GP Holdings LLC | 9.9% | ||
| BVF Partners L P/IL | 10.0% | ||
| BVF Inc/IL | 10.0% | ||
| Lampert Mark N | 10.0% | ||
| Woodline Partners LP 13G | 9.9% |
11/14/2025
Event 9/30/2025
|
|
|
Commodore Capital LP
13G
|
9.9% |
10/3/2025
Event 9/26/2025
|
|
| Commodore Capital LP | 9.9% | ||
| Commodore Capital Master LP | 9.9% | ||
| Robert Egen Atkinson | 9.9% | ||
| Michael Kramarz | 9.9% | ||
|
RA Capital Management, L.P.
13D
|
9.9% |
10/3/2025
Event 9/26/2025
|
|
| RA Capital Management, L.P. | 9.9% | ||
| Peter Kolchinsky | 9.9% | ||
| Rajeev Shah | 9.9% | ||
| RA Capital Healthcare Fund, L.P. | 9.9% | ||
|
Vivo Opportunity Fund Holdings, L.P.
13G
|
10.0% |
10/3/2025
Event 9/29/2025
|
|
| Vivo Opportunity Fund Holdings, L.P. | 10.0% | ||
| Vivo Opportunity, LLC | 10.0% | ||
| Vivo Opportunity Cayman Fund, L.P. | 10.0% | ||
| Vivo Opportunity Cayman, LLC | 10.0% | ||
|
RTW Investments, LP
13G/A
Amendment 1
|
10.0% |
2/14/2025
Event 12/31/2024
|
|
| RTW Investments, LP | 10.0% | ||
| Roderick Wong, M.D. | 10.0% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 1 | 21.0 | $67.00 |
| 2026 Q2 | 92 | 68.4 M | $267 M |
| 2026 Q1 | 83 | 69.6 M | $266 M |
| 2025 Q4 | 48 | 36.3 M | $136 M |
| 2025 Q3 | 35 | 28.0 M | $56.3 M |
| 2025 Q2 | 26 | 1.92 M | $3.37 M |
| 2025 Q1 | 27 | 2.21 M | $2.99 M |
| 2024 Q4 | 27 | 2.65 M | $10.2 M |
| 2024 Q3 | 27 | 3.14 M | $8.48 M |
| 2024 Q2 | 25 | 3.13 M | $9.70 M |
| 2024 Q1 | 28 | 3.34 M | $15.2 M |
| 2023 Q4 | 3 | 8.79 M | $6.06 M |