| Quarter | Holdings | Value ($000) | Top Holdings | Form Type | Date Filed | Filing ID |
|---|---|---|---|---|---|---|
| Q4 2023 | 64 | 6,401,901 | RCKT, IMCR, MRTX, AXSM | 13F-HR | 2/14/2024 | 000149315224006286 |
| Q3 2023 | 67 | 4,739,611 | RCKT, IMCR, AXSM, ALNY | 13F-HR | 11/14/2023 | 000149315223040729 |
| Q2 2023 | 62 | 5,252,749 | IMCR, RCKT, ALNY, AXSM | 13F-HR | 8/14/2023 | 000149315223028029 |
| Q1 2023 | 60 | 4,802,152 | RXDX, PTCT, ALNY, RCKT | 13F-HR | 5/15/2023 | 000149315223016865 |
| Q4 2022 | 77 | 4,898,669 | ALNY, RXDX, RCKT, IMCR | 13F-HR | 2/14/2023 | 000149315223004608 |
| Q3 2022 | 86 | 4,337,602 | ALNY, PTCT, RCKT, TMO | 13F-HR | 11/14/2022 | 000149315222032245 |
| Q2 2022 | 107 | 3,870,398 | ALNY, TMO, RCKT, PTCT | 13F-HR | 8/15/2022 | 000149315222022708 |
| Q1 2022 | 106 | 4,831,643 | ALNY, RCKT, TMO, PTCT | 13F-HR | 5/16/2022 | 000149315222013567 |
| Q4 2021 | 124 | 6,848,327 | SPY, RCKT, ALNY, TMO | 13F-HR | 2/14/2022 | 000149315222004326 |
| Q3 2021 | 120 | 6,630,943 | RCKT, SPY, ALNY, MRTX | 13F-HR | 11/15/2021 | 000149315221028680 |
| Q2 2021 | 113 | 6,627,028 | RCKT, SPY, ALNY, DRNA | 13F-HR | 8/13/2021 | 000149315221019742 |
| Q1 2021 | 111 | 6,405,753 | RCKT, SPY, VCEL, PTCT | 13F-HR | 5/14/2021 | 000149315221011440 |
| Q4 2020 | 102 | 5,960,264 | RCKT, IMVT, PTCT, MRTX | 13F-HR | 2/16/2021 | 000149315221003922 |
| Q3 2020 | 90 | 4,153,392 | RCKT, IMVT, ALNY, PTCT | 13F-HR | 11/16/2020 | 000149315220021624 |
| Q2 2020 | 77 | 3,554,553 | RCKT, ALNY, PTCT, DRNA | 13F-HR | 8/14/2020 | 000149315220015797 |
| Q1 2020 | 65 | 2,323,157 | RCKT, ALNY, PTCT, DRNA | 13F-HR | 5/15/2020 | 000149315220009119 |
| Q4 2019 | 60 | 2,629,866 | RCKT, ALNY, PTCT, DRNA | 13F-HR | 2/14/2020 | 000149315220002338 |
| Q4 2019 | 1 | 20,485 | MDXG | NEW HOLDINGS | 2/14/2020 | 000149315220002551 |
| Q3 2019 | 60 | 1,681,540 | RCKT, ALNY, PTCT, DRNA | 13F-HR | 11/14/2019 | 000149315219017406 |
| Q2 2019 | 52 | 1,872,338 | RCKT, ALNY, PTCT, DRNA | 13F-HR | 8/14/2019 | 000149315219012319 |
| Q1 2019 | 50 | 1,465,018 | RCKT, PTCT, DRNA, ALNY | 13F-HR | 5/15/2019 | 000149315219007228 |
| Q4 2018 | 47 | 1,074,391 | RCKT, ARWR, PTCT, DRNA | RESTATEMENT | 2/15/2019 | 000149315219002186 |
| Q4 2018 | 1 | 15,500 | Bovie Medical Corp | NEW HOLDINGS | 2/15/2019 | 000149315219002190 |
| Q3 2018 | 46 | 1,670,201 | RCKT, PTCT, ARWR, RGNX | 13F-HR | 11/14/2018 | 000149315218015906 |
| Q2 2018 | 40 | 1,386,575 | RCKT, RGNX, PTCT, SRPT | 13F-HR | 8/14/2018 | 000149315218011640 |
| Q1 2018 | 38 | 1,050,780 | RCKT, PTCT, BMY, RGNX | 13F-HR | 5/14/2018 | 000149315218006734 |
| Q4 2017 | 32 | 599,105 | PTCT, RGNX, BMY, ALNY | RESTATEMENT | 2/28/2018 | 000149315218002731 |
| Q3 2017 | 27 | 574,197 | ALNY, PTCT, BMY, RGNX | 13F-HR | 11/14/2017 | 000149315217012995 |
| Q2 2017 | 28 | 474,374 | ALNY, PTCT, AVXS, BMY | 13F-HR | 8/14/2017 | 000149315217009184 |
| Q1 2017 | 28 | 379,902 | ALNY, AVXS, BMY, LJPC | 13F-HR | 5/15/2017 | 000149315217005309 |
| Q4 2016 | 32 | 265,662 | AVXS, BMY, ALNY, BCRX | 13F-HR | 2/15/2017 | 000149315217001592 |
| Q3 2016 | 36 | 330,886 | ALNY, AVXS, AGEN, LJPC | RESTATEMENT | 11/18/2016 | 000149315216015263 |
| Q2 2016 | 35 | 292,692 | ALNY, INCY, BLUE, ACHN | 13F-HR | 8/15/2016 | 000149315216012354 |
| Q1 2016 | 34 | 275,445 | ALNY, INCY, LJPC, ACHN | 13F-HR | 5/11/2016 | 000149315216009638 |
| Q4 2015 | 29 | 302,756 | ALNY, LJPC, OMER, KITE | RESTATEMENT | 5/24/2016 | 000149315216010244 |
| Q4 2015 | 9 | 4,630 | MASI, ANIK, MDRX, Genomic Health Inc | NEW HOLDINGS | 5/24/2016 | 000149315216010245 |
| Q3 2015 | 44 | 321,849 | ALNY, INCY, LJPC, BCRX | RESTATEMENT | 5/24/2016 | 000149315216010243 |
| Q2 2015 | 35 | 343,537 | ALNY, BCRX, KITE, ACHN | 13F-HR | 8/14/2015 | 000090901215000277 |
| Q1 2015 | 24 | 221,515 | ALNY, DYAX, DRNA, KITE | 13F-HR | 5/21/2015 | 000090901215000223 |
| Q4 2014 | 21 | 270,288 | TARO, ALNY, DYAX, BCRX | 13F-HR | 2/17/2015 | 000091957415001784 |