Investors who own more than 5% of a class must file a Schedule 13D or 13G. Each filer's latest filing for 171757206 since 12/18/2024, largest first.
| Filer | % of Class | Filed | ||
|---|---|---|---|---|
| Vanguard Group Inc 13G | 6.4% |
1/30/2026
Event 12/31/2025
|
||
| Under 5%, checked the "5 percent or less" box, or amended by a later filing (12) | ||||
|
Adage Capital Management, L.P.
13G/A
|
4.97% |
8/12/2025
Event 6/30/2025
|
||
| Adage Capital Management, L.P. | 4.97% | |||
| Robert Atchinson | 4.97% | |||
| Phillip Gross | 4.97% | |||
| BlackRock, Inc. 13G/A | 4.6% |
10/17/2025
Event 9/30/2025
|
||
|
Biotechnology Value Fund L P
13G/A
|
4.4% |
10/17/2025
Event 10/15/2025
|
||
| Biotechnology Value Fund L P | 2.3% | |||
| BVF I GP LLC | 2.3% | |||
| Biotechnology Value Fund II LP | 1.7% | |||
| BVF II GP LLC | 1.7% | |||
| Biotechnology Value Trading Fund OS LP | 0.3% | |||
| BVF Partners OS Ltd. | 0.3% | |||
| BVF GP Holdings LLC | 4.0% | |||
| BVF Partners L P/IL | 4.4% | |||
| BVF Inc/IL | 4.4% | |||
| Lampert Mark N | 4.4% | |||
|
Paradigm Biocapital Advisors LP
13G/A
|
3.3% |
11/14/2025
Event 9/30/2025
|
||
| Paradigm BioCapital Advisors LP | 3.3% | |||
| Paradigm BioCapital Advisors GP LLC | 3.3% | |||
| Senai Asefaw, M.D. | 3.3% | |||
| Paradigm BioCapital International Fund Ltd. | 2.9% | |||
|
Venrock Healthcare Capital Partners III, L.P.
13G/A
|
3.2% |
8/14/2025
Event 6/30/2025
|
||
| Venrock Healthcare Capital Partners III, L.P. | 3.2% | |||
| VHCP Co-Investment Holdings III, LLC | 3.2% | |||
| Venrock Healthcare Capital Partners EG, L.P. | 3.2% | |||
| VHCP Management III, LLC | 3.2% | |||
| VHCP Management EG, LLC | 3.2% | |||
| Nimish Shah | 3.2% | |||
| Bong Y. Koh | 3.2% | |||
|
Commodore Capital LP
13G/A
|
2.0% |
11/14/2025
Event 9/30/2025
|
||
| Commodore Capital LP | 2.0% | |||
| Commodore Capital Master LP | 2.0% | |||
| Robert Egen Atkinson | 2.0% | |||
| Michael Kramarz | 2.0% | |||
|
Point72 Asset Management, L.P.
13G/A
|
1.4% |
2/17/2026
Event 12/31/2025
|
||
| Point72 Asset Management, L.P. | 1.4% | |||
| Point72 Capital Advisors, Inc. | 1.4% | |||
| Steven A. Cohen | 1.4% | |||
| BCLS Fund III Investments, LP 13G/A | 0% |
2/17/2026
Event 12/31/2025
|
||
|
Canaan XII L.P.
13G/A
|
0% |
8/14/2025
Event 6/30/2025
|
||
| Canaan XII L.P. | 0% | |||
| Canaan Partners XII LLC | 0% | |||
|
RA Capital Management, L.P.
13D/A
|
0% |
1/9/2026
Event 1/7/2026
|
||
| RA Capital Management, L.P. | 0% | |||
| Peter Kolchinsky | 0% | |||
| Rajeev Shah | 0% | |||
| RA Capital Healthcare Fund, L.P. | 0% | |||
|
TCG Crossover GP II, LLC
13G/A
|
0% |
11/14/2025
Event 9/30/2025
|
||
| TCG Crossover GP II, LLC | 0% | |||
| TCG Crossover Fund II, L.P. | 0% | |||
| Chen Yu | 0% | |||
|
Vivo Opportunity Fund Holdings, L.P.
13G/A
|
0% |
2/13/2026
Event 1/7/2026
|
||
| Vivo Opportunity Fund Holdings, L.P. | 0% | |||
| Vivo Opportunity, LLC | 0% | |||
| Vivo Opportunity Cayman Fund, L.P. | 0% | |||
| Vivo Opportunity Cayman, LLC | 0% | |||