Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 171757206 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
| BCLS Fund III Investments, LP 13G/A Amendment 3 | 0% |
2/17/2026
Event 12/31/2025
|
|
|
Point72 Asset Management, L.P.
13G/A
Amendment 3
|
1.4% |
2/17/2026
Event 12/31/2025
|
|
| Point72 Asset Management, L.P. | 1.4% | ||
| Point72 Capital Advisors, Inc. | 1.4% | ||
| Steven A. Cohen | 1.4% | ||
|
Vivo Opportunity Fund Holdings, L.P.
13G/A
Amendment 3
|
0% |
2/13/2026
Event 1/7/2026
|
|
| Vivo Opportunity Fund Holdings, L.P. | 0% | ||
| Vivo Opportunity, LLC | 0% | ||
| Vivo Opportunity Cayman Fund, L.P. | 0% | ||
| Vivo Opportunity Cayman, LLC | 0% | ||
| Vanguard Group Inc 13G | 6.4% |
1/30/2026
Event 12/31/2025
|
|
|
RA Capital Management, L.P.
13D/A
Amendment 6
|
0% |
1/9/2026
Event 1/7/2026
|
|
| RA Capital Management, L.P. | 0% | ||
| Peter Kolchinsky | 0% | ||
| Rajeev Shah | 0% | ||
| RA Capital Healthcare Fund, L.P. | 0% | ||
|
RA Capital Management, L.P.
13D/A
Amendment 5
|
10.7% |
11/17/2025
Event 11/13/2025
|
|
| RA Capital Management, L.P. | 10.7% | ||
| Peter Kolchinsky | 10.7% | ||
| Rajeev Shah | 10.7% | ||
| RA Capital Healthcare Fund, L.P. | 10.7% | ||
|
Commodore Capital LP
13G/A
Amendment 1
|
2.0% |
11/14/2025
Event 9/30/2025
|
|
| Commodore Capital LP | 2.0% | ||
| Commodore Capital Master LP | 2.0% | ||
| Robert Egen Atkinson | 2.0% | ||
| Michael Kramarz | 2.0% | ||
| BCLS Fund III Investments, LP 13G/A Amendment 2 | 10.0% |
11/14/2025
Event 9/30/2025
|
|
|
TCG Crossover GP II, LLC
13G/A
Amendment 1
|
0% |
11/14/2025
Event 9/30/2025
|
|
| TCG Crossover GP II, LLC | 0% | ||
| TCG Crossover Fund II, L.P. | 0% | ||
| Chen Yu | 0% | ||
|
Paradigm Biocapital Advisors LP
13G/A
Amendment 1
|
3.3% |
11/14/2025
Event 9/30/2025
|
|
| Paradigm BioCapital Advisors LP | 3.3% | ||
| Paradigm BioCapital Advisors GP LLC | 3.3% | ||
| Senai Asefaw, M.D. | 3.3% | ||
| Paradigm BioCapital International Fund Ltd. | 2.9% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 2
|
6.2% |
11/14/2025
Event 9/30/2025
|
|
| Point72 Asset Management, L.P. | 6.2% | ||
| Point72 Capital Advisors, Inc. | 6.2% | ||
| Steven A. Cohen | 6.2% | ||
|
RA Capital Management, L.P.
13D/A
Amendment 4
|
10.7% |
11/10/2025
Event 11/6/2025
|
|
| RA Capital Management, L.P. | 10.7% | ||
| Peter Kolchinsky | 10.7% | ||
| Rajeev Shah | 10.7% | ||
| RA Capital Healthcare Fund, L.P. | 10.7% | ||
| BlackRock, Inc. 13G/A Amendment 1 | 4.6% |
10/17/2025
Event 9/30/2025
|
|
|
Biotechnology Value Fund L P
13G/A
Amendment 10
|
4.4% |
10/17/2025
Event 10/15/2025
|
|
| Biotechnology Value Fund L P | 2.3% | ||
| BVF I GP LLC | 2.3% | ||
| Biotechnology Value Fund II LP | 1.7% | ||
| BVF II GP LLC | 1.7% | ||
| Biotechnology Value Trading Fund OS LP | 0.3% | ||
| BVF Partners OS Ltd. | 0.3% | ||
| BVF GP Holdings LLC | 4.0% | ||
| BVF Partners L P/IL | 4.4% | ||
| BVF Inc/IL | 4.4% | ||
| Lampert Mark N | 4.4% | ||
|
Biotechnology Value Fund L P
13G/A
Amendment 9
|
5.2% |
10/17/2025
Event 9/30/2025
|
|
| Biotechnology Value Fund L P | 2.7% | ||
| BVF I GP LLC | 2.7% | ||
| Biotechnology Value Fund II LP | 2.1% | ||
| BVF II GP LLC | 2.1% | ||
| Biotechnology Value Trading Fund OS LP | 0.3% | ||
| BVF Partners OS Ltd. | 0.3% | ||
| BVF GP Holdings LLC | 4.8% | ||
| BVF Partners L P/IL | 5.2% | ||
| BVF Inc/IL | 5.2% | ||
| Lampert Mark N | 5.2% | ||
|
Venrock Healthcare Capital Partners III, L.P.
13G/A
Amendment 2
|
3.2% |
8/14/2025
Event 6/30/2025
|
|
| Venrock Healthcare Capital Partners III, L.P. | 3.2% | ||
| VHCP Co-Investment Holdings III, LLC | 3.2% | ||
| Venrock Healthcare Capital Partners EG, L.P. | 3.2% | ||
| VHCP Management III, LLC | 3.2% | ||
| VHCP Management EG, LLC | 3.2% | ||
| Nimish Shah | 3.2% | ||
| Bong Y. Koh | 3.2% | ||
|
Venrock Healthcare Capital Partners III, L.P.
13G/A
Amendment 2
|
9.9% |
8/14/2025
Event 6/30/2025
|
|
| Venrock Healthcare Capital Partners III, L.P. | 9.9% | ||
| VHCP Co-Investment Holdings III, LLC | 9.9% | ||
| Venrock Healthcare Capital Partners EG, L.P. | 9.9% | ||
| VHCP Management III, LLC | 9.9% | ||
| VHCP Management EG, LLC | 9.9% | ||
| Nimish Shah | 9.9% | ||
| Bong Y. Koh | 9.9% | ||
|
Canaan XII L.P.
13G/A
Amendment 1
|
0% |
8/14/2025
Event 6/30/2025
|
|
| Canaan XII L.P. | 0% | ||
| Canaan Partners XII LLC | 0% | ||
| BCLS Fund III Investments, LP 13G/A Amendment 1 | 10.0% |
8/14/2025
Event 6/30/2025
|
|
|
Point72 Asset Management, L.P.
13G/A
Amendment 1
|
7.6% |
8/14/2025
Event 6/30/2025
|
|
| Point72 Asset Management, L.P. | 7.6% | ||
| Point72 Capital Advisors, Inc. | 7.6% | ||
| Steven A. Cohen | 7.6% | ||
|
Vivo Opportunity Fund Holdings, L.P.
13G/A
Amendment 2
|
4.6% |
8/12/2025
Event 6/30/2025
|
|
| Vivo Opportunity Fund Holdings, L.P. | 4.6% | ||
| Vivo Opportunity, LLC | 4.6% | ||
| Vivo Opportunity Cayman Fund, L.P. | 0.5% | ||
| Vivo Opportunity Cayman, LLC | 0.5% | ||
|
Adage Capital Management, L.P.
13G/A
Amendment 1
|
4.97% |
8/12/2025
Event 6/30/2025
|
|
| Adage Capital Management, L.P. | 4.97% | ||
| Robert Atchinson | 4.97% | ||
| Phillip Gross | 4.97% | ||
|
RA Capital Management, L.P.
13D/A
Amendment 3
|
13.3% |
8/11/2025
Event 8/7/2025
|
|
| RA Capital Management, L.P. | 13.3% | ||
| Peter Kolchinsky | 13.3% | ||
| Rajeev Shah | 13.3% | ||
| RA Capital Healthcare Fund, L.P. | 13.3% | ||
|
Paradigm Biocapital Advisors LP
13G
|
5.6% |
7/30/2025
Event 7/23/2025
|
|
| Paradigm BioCapital Advisors LP | 5.6% | ||
| Paradigm BioCapital Advisors GP LLC | 5.6% | ||
| Senai Asefaw, M.D. | 5.6% | ||
| Paradigm BioCapital International Fund Ltd. | 4.9% | ||
| BlackRock, Inc. 13G | 5.5% |
7/17/2025
Event 6/30/2025
|
|
|
Commodore Capital LP
13G
|
5.5% |
7/2/2025
Event 6/25/2025
|
|
| Commodore Capital LP | 5.5% | ||
| Commodore Capital Master LP | 5.5% | ||
| Robert Egen Atkinson | 5.5% | ||
| Michael Kramarz | 5.5% | ||
|
RA Capital Management, L.P.
13D/A
Amendment 2
|
15.8% |
6/30/2025
Event 6/26/2025
|
|
| RA Capital Management, L.P. | 15.8% | ||
| Peter Kolchinsky | 15.8% | ||
| Rajeev Shah | 15.8% | ||
| RA Capital Healthcare Fund, L.P. | 15.8% | ||
|
Venrock Healthcare Capital Partners III, L.P.
13G/A
Amendment 1
|
9.9% |
5/15/2025
Event 3/31/2025
|
|
| Venrock Healthcare Capital Partners III, L.P. | 9.9% | ||
| VHCP Co-Investment Holdings III, LLC | 9.9% | ||
| Venrock Healthcare Capital Partners EG, L.P. | 9.9% | ||
| VHCP Management III, LLC | 9.9% | ||
| VHCP Management EG, LLC | 9.9% | ||
| Nimish Shah | 9.9% | ||
| Bong Y Koh | 9.9% | ||
|
Venrock Healthcare Capital Partners III, L.P.
13G/A
Amendment 1
|
9.9% |
5/15/2025
Event 3/31/2025
|
|
| Venrock Healthcare Capital Partners III, L.P. | 9.9% | ||
| VHCP Co-Investment Holdings III, LLC | 9.9% | ||
| Venrock Healthcare Capital Partners EG, L.P. | 9.9% | ||
| VHCP Management III, LLC | 9.9% | ||
| VHCP Management EG, LLC | 9.9% | ||
| Nimish Shah | 9.9% | ||
| Bong Y Koh | 9.9% | ||
|
Vivo Opportunity Fund Holdings, L.P.
13G/A
Amendment 1
|
4.7% |
5/15/2025
Event 3/31/2025
|
|
| Vivo Opportunity Fund Holdings, L.P. | 4.7% | ||
| Vivo Opportunity, LLC | 4.7% | ||
| Vivo Opportunity Cayman Fund, L.P. | 0.6% | ||
| Vivo Opportunity Cayman, LLC | 0.6% | ||
|
Biotechnology Value Fund L P
13G/A
Amendment 8
|
10.0% |
5/15/2025
Event 3/31/2025
|
|
| Biotechnology Value Fund L P | 5.8% | ||
| BVF I GP LLC | 5.8% | ||
| Biotechnology Value Fund II LP | 3.8% | ||
| BVF II GP LLC | 3.8% | ||
| Biotechnology Value Trading Fund OS LP | 0.4% | ||
| BVF Partners OS Ltd. | 0.4% | ||
| BVF GP Holdings LLC | 9.4% | ||
| BVF Partners L P/IL | 10.0% | ||
| BVF Inc/IL | 10.0% | ||
| Lampert Mark N | 10.0% | ||
|
Adage Capital Management, L.P.
13G
|
9.0% |
5/12/2025
Event 3/31/2025
|
|
| Adage Capital Management, L.P. | 9.0% | ||
| Robert Atchinson | 9.0% | ||
| Phillip Gross | 9.0% | ||
|
Point72 Asset Management, L.P.
13G
|
9.1% |
4/16/2025
Event 4/9/2025
|
|
| Point72 Asset Management, L.P. | 9.1% | ||
| Point72 Capital Advisors, Inc. | 9.1% | ||
| Steven A. Cohen | 9.1% | ||
|
Biotechnology Value Fund L P
13G/A
Amendment 7
|
10.0% |
2/14/2025
Event 12/31/2024
|
|
| Biotechnology Value Fund L P | 4.5% | ||
| BVF I GP LLC | 4.5% | ||
| Biotechnology Value Fund II LP | 4.5% | ||
| BVF II GP LLC | 4.5% | ||
| Biotechnology Value Trading Fund OS LP | 0.6% | ||
| BVF Partners OS Ltd. | 0.6% | ||
| BVF GP Holdings LLC | 9.0% | ||
| BVF Partners L P/IL | 10.0% | ||
| BVF Inc/IL | 10.0% | ||
| Lampert Mark N | 10.0% |