Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 045396207 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Paradigm Biocapital Advisors LP
13G/A
Amendment 1
|
7.8% |
8/14/2026
Event 6/30/2026
|
|
| Paradigm BioCapital Advisors LP | 7.8% | ||
| Paradigm BioCapital Advisors GP LLC | 7.8% | ||
| Senai Asefaw, M.D. | 7.8% | ||
| Paradigm BioCapital International Fund Ltd. | 6.9% | ||
| Janus Henderson Group Ltd. 13G/A Amendment 1 | 6.9% |
8/13/2026
Event 6/30/2026
|
|
|
Farallon Capital Management, L.L.C.
13G/A
Amendment 2
|
8.1% |
8/4/2026
Event 6/30/2026
|
|
| Farallon Capital Management, L.L.C. | 8.1% | ||
| Farallon Capital Partners, L.P. | 0% | ||
| Farallon Capital Institutional Partners, L.P. | 0% | ||
| Farallon Capital Institutional Partners II, L.P. | 0% | ||
| Farallon Capital Institutional Partners III, L.P. | 0% | ||
| Four Crossings Institutional Partners V, L.P. | 0% | ||
| Farallon Capital Offshore Investors II, L.P. | 0% | ||
| Farallon Capital (AM) Investors, L.P. | 0% | ||
| Farallon Capital F5 Master I, L.P. | 0% | ||
| Farallon Partners, L.L.C. | 0% | ||
| Farallon Institutional (GP) V, L.L.C. | 0% | ||
| Farallon F5 (GP), L.L.C. | 0% | ||
| Dapice Joshua J. | 8.1% | ||
| Dreyfuss, Philip D. | 8.1% | ||
| Dunn Hannah E. | 8.1% | ||
| Gehani, Varun N. | 8.1% | ||
| Giauque, Nicolas | 8.1% | ||
| Husen, Avner A. | 8.1% | ||
| Kim, David T. | 8.1% | ||
| Linn, Michael G. | 8.1% | ||
| Luo Patrick (Cheng) | 8.1% | ||
| Roberts, Jr., Thomas G. | 8.1% | ||
| Saito Edric C. | 8.1% | ||
| Short Daniel S. | 8.1% | ||
| Spokes, Andrew J. M. | 8.1% | ||
| Warren, John R. | 8.1% | ||
| Wehrly, Mark C. | 8.1% | ||
|
Paradigm Biocapital Advisors LP
13G
|
5.4% |
5/11/2026
Event 5/4/2026
|
|
| Paradigm BioCapital Advisors LP | 5.4% | ||
| Paradigm BioCapital Advisors GP LLC | 5.4% | ||
| Senai Asefaw, M.D. | 5.4% | ||
| Paradigm BioCapital International Fund Ltd. | 4.8% | ||
|
Farallon Capital Partners, L.P.
13G/A
Amendment 1
|
7.8% |
2/9/2026
Event 12/31/2025
|
|
| Farallon Capital Partners, L.P. | 1.5% | ||
| Farallon Capital Institutional Partners, L.P. | 1.4% | ||
| Farallon Capital Institutional Partners II, L.P. | 0.5% | ||
| Farallon Capital Institutional Partners III, L.P. | 0.3% | ||
| Four Crossings Institutional Partners V, L.P. | 0.4% | ||
| Farallon Capital Offshore Investors II, L.P. | 3.1% | ||
| Farallon Capital (AM) Investors, L.P. | 0.2% | ||
| Farallon Capital F5 Master I, L.P. | 0.3% | ||
| Farallon Partners, L.L.C. | 7.4% | ||
| Farallon Institutional (GP) V, L.L.C. | 0.4% | ||
| Farallon F5 (GP), L.L.C. | 0.3% | ||
| Dapice Joshua J. | 7.8% | ||
| Dreyfuss, Philip D. | 7.8% | ||
| Dunn Hannah E. | 7.8% | ||
| Fried, Richard B | 0% | ||
| Gehani, Varun N. | 7.8% | ||
| Giauque, Nicolas | 7.8% | ||
| Husen, Avner A. | 7.8% | ||
| Kim, David T. | 7.8% | ||
| Linn, Michael G. | 7.8% | ||
| Luo Patrick (Cheng) | 7.8% | ||
| Patel, Rajiv A. | 0% | ||
| Roberts, Jr., Thomas G. | 7.8% | ||
| Saito Edric C. | 7.8% | ||
| Seybold, William | 0% | ||
| Short Daniel S. | 7.8% | ||
| Spokes, Andrew J. M. | 7.8% | ||
| Warren, John R. | 7.8% | ||
| Wehrly, Mark C. | 7.8% | ||
| Janus Henderson Group PLC 13G | 8.2% |
12/8/2025
Event 11/28/2025
|
|
|
RA Capital Management, L.P.
13G
|
9.5% |
8/18/2025
Event 8/11/2025
|
|
| RA Capital Management, L.P. | 9.5% | ||
| Peter Kolchinsky | 9.5% | ||
| Rajeev Shah | 9.5% | ||
| RA Capital Healthcare Fund, L.P. | 9.5% | ||
| Alexander Schornstein 13G/A Amendment 3 | 3.5% |
8/18/2025
Event 8/11/2025
|
|
|
Commodore Capital LP
13G
|
9.9% |
8/15/2025
Event 8/8/2025
|
|
| Commodore Capital LP | 9.9% | ||
| Commodore Capital Master LP | 9.9% | ||
| Robert Egen Atkinson | 9.9% | ||
| Michael Kramarz | 9.9% | ||
|
Farallon Capital Partners, L.P.
13G
|
7.3% |
8/15/2025
Event 8/8/2025
|
|
| Farallon Capital Partners, L.P. | 1.4% | ||
| Farallon Capital Institutional Partners, L.P. | 1.3% | ||
| Farallon Capital Institutional Partners II, L.P. | 0.4% | ||
| Farallon Capital Institutional Partners III, L.P. | 0.3% | ||
| Four Crossings Institutional Partners V, L.P. | 0.3% | ||
| Farallon Capital Offshore Investors II, L.P. | 3.0% | ||
| Farallon Capital (AM) Investors, L.P. | 0.2% | ||
| Farallon Capital F5 Master I, L.P. | 0.3% | ||
| Farallon Partners, L.L.C. | 7.0% | ||
| Farallon Institutional (GP) V, L.L.C. | 0.3% | ||
| Farallon F5 (GP), L.L.C. | 0.3% | ||
| Dapice Joshua J. | 7.3% | ||
| Dreyfuss, Philip D. | 7.3% | ||
| Dunn Hannah E. | 7.3% | ||
| Fried, Richard B | 7.3% | ||
| Gehani, Varun N. | 7.3% | ||
| Giauque, Nicolas | 7.3% | ||
| Kim, David T. | 7.3% | ||
| Linn, Michael G. | 7.3% | ||
| Luo Patrick (Cheng) | 7.3% | ||
| Patel, Rajiv A. | 7.3% | ||
| Roberts, Jr., Thomas G. | 7.3% | ||
| Saito Edric C. | 7.3% | ||
| Seybold, William | 7.3% | ||
| Short Daniel S. | 7.3% | ||
| Spokes, Andrew J. M. | 7.3% | ||
| Warren, John R. | 7.3% | ||
| Wehrly, Mark C. | 7.3% | ||
|
Armistice Capital, LLC
13G/A
Amendment 3
|
10.0% |
8/14/2025
Event 6/30/2025
|
|
| Armistice Capital, LLC | 10.0% | ||
| Steven Boyd | 10.0% | ||
| Alexander Schornstein 13G | 4.7% |
8/12/2025
Event 8/11/2025
|
|
|
Armistice Capital, LLC
13G/A
Amendment 1
|
4.99% |
2/14/2025
Event 12/31/2024
|
|
| Armistice Capital, LLC | 4.99% | ||
| Steven Boyd | 4.99% | ||
| Alexander Schornstein 13G/A Amendment 1 | 10.0% |
12/23/2024
Event 12/19/2024
|
|
| Alexander Schornstein 13G | 10.0% |
12/23/2024
Event 6/24/2024
|
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 1 | 20.0 | $470.00 |
| 2026 Q2 | 96 | 18.8 M | $515 M |
| 2026 Q1 | 76 | 13.8 M | $382 M |
| 2025 Q4 | 69 | 13.7 M | $467 M |
| 2025 Q3 | 60 | 12.5 M | $325 M |
| 2025 Q2 | 35 | 3.15 M | $57.1 M |
| 2025 Q1 | 38 | 3.18 M | $30.4 M |
| 2024 Q4 | 36 | 3.19 M | $50.3 M |
| 2024 Q3 | 32 | 1.03 M | $15.6 M |
| 2024 Q2 | 31 | 1.18 M | $16.1 M |
| 2024 Q1 | 28 | 652 k | $8.68 M |