Investors who own more than 5% of a class must file a Schedule 13D or 13G. Each filer's latest filing for 014442107 since 12/18/2024.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
TCG Crossover GP II, LLC
13G
|
9.2% |
11/14/2025
Event 10/22/2025
|
|
| TCG Crossover GP II, LLC | 4.6% | ||
| TCG Crossover Fund II, L.P. | 4.6% | ||
| TCG Crossover GP III, LLC | 4.6% | ||
| TCG Crossover Fund III, L.P. | 4.6% | ||
| Chen Yu | 9.2% | ||
|
Biotechnology Value Fund L P
13G
|
8.4% |
9/18/2026
Event 9/11/2026
|
|
| Biotechnology Value Fund L P | 4.4% | ||
| BVF I GP LLC | 4.4% | ||
| Biotechnology Value Fund II LP | 3.3% | ||
| BVF II GP LLC | 3.3% | ||
| Biotechnology Value Trading Fund OS LP | 0.6% | ||
| BVF Partners OS Ltd. | 0.6% | ||
| BVF GP Holdings LLC | 7.7% | ||
| BVF Partners L P/IL | 8.4% | ||
| BVF Inc/IL | 8.4% | ||
| Lampert Mark N | 8.4% | ||
| Arnon Rosenthal 13G/A | 7.4% |
2/6/2026
Event 12/31/2025
|
|
| BlackRock, Inc. 13G | 5.2% |
4/27/2026
Event 3/31/2026
|
|
| Under 5%, or checked the "5 percent or less" box (5) | |||
|
Polaris Venture Partners VI, L.P.
13G/A
|
4.7% |
5/14/2026
Event 3/31/2026
|
|
| Polaris Venture Partners VI, L.P. | 0.5% | ||
| Polaris Venture Partners Founders' Fund VI, L.P. | 0.2% | ||
| Polaris Venture Partners VI (AIV), L.P. | 3.0% | ||
| Polaris Venture Partners VI (AIV-B), L.P. | 0.7% | ||
| Polaris Venture Management Co VI, L.L.C. | 4.4% | ||
| David Barrett | 4.4% | ||
| Brian Chee | 4.4% | ||
| Jonathan A. Flint | 4.4% | ||
| Terrance G. McGuire | 4.7% | ||
| Amir Nashat | 4.5% | ||
| Bryce Youngren | 4.4% | ||
|
FMR LLC
13G/A
|
3.6% |
11/7/2025
Event 10/31/2025
|
|
| FMR LLC | 3.6% | ||
| Abigail P. Johnson | 3.6% | ||
|
RA Capital Management, L.P.
13G/A
|
0% |
8/14/2025
Event 6/30/2025
|
|
| RA Capital Management, L.P. | 0% | ||
| Peter Kolchinsky | 0% | ||
| Rajeev Shah | 0% | ||
| RA Capital Healthcare Fund, L.P. | 0% | ||
|
RTW Investments, LP
13G/A
|
0% |
2/17/2026
Event 12/31/2025
|
|
| RTW Investments, LP | 0% | ||
| Roderick Wong | 0% | ||
| Vanguard Group Inc 13G/A | 0% |
3/26/2026
Event 3/13/2026
|
|
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q2 | 149 | 95.9 M | $194 M |
| 2026 Q1 | 142 | 88.4 M | $190 M |
| 2025 Q4 | 139 | 84.5 M | $132 M |
| 2025 Q3 | 157 | 74.9 M | $222 M |
| 2025 Q2 | 140 | 71.4 M | $100 M |
| 2025 Q1 | 146 | 72.6 M | $89.8 M |
| 2024 Q4 | 155 | 73.4 M | $139 M |
| 2024 Q3 | 168 | 75.3 M | $351 M |
| 2024 Q2 | 168 | 77.4 M | $352 M |
| 2024 Q1 | 166 | 82.5 M | $497 M |
| 2023 Q4 | 157 | 70.7 M | $564 M |
| 2023 Q3 | 157 | 63.5 M | $412 M |
| 2023 Q2 | 149 | 59.0 M | $355 M |
| 2023 Q1 | 157 | 58.4 M | $361 M |
| 2022 Q4 | 164 | 58.1 M | $536 M |
| 2022 Q3 | 176 | 54.7 M | $517 M |
| 2022 Q2 | 160 | 53.8 M | $547 M |
| 2022 Q1 | 175 | 55.5 M | $791 M |
| 2021 Q4 | 181 | 55.0 M | $1.14 B |
| 2021 Q3 | 156 | 52.2 M | $1.19 B |
| 2021 Q2 | 152 | 49.2 M | $1.02 B |
| 2021 Q1 | 137 | 46.3 M | $932 M |
| 2020 Q4 | 151 | 46.4 M | $703 M |
| 2020 Q3 | 153 | 49.5 M | $522 M |
| 2020 Q2 | 148 | 50.1 M | $1.22 B |
| 2020 Q1 | 114 | 47.9 M | $1.16 B |
| 2019 Q4 | 85 | 37.5 M | $646 M |
| 2019 Q3 | 78 | 35.5 M | $512 M |
| 2019 Q2 | 64 | 29.1 M | $551 M |
| 2019 Q1 | 55 | 28.7 M | $526 M |