Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 98401F105 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
| Vanguard Capital Management LLC 13G | 5.1% |
7/31/2026
Event 6/30/2026
|
|
|
EcoR1 Capital, LLC
13G/A
Amendment 6
|
2.9% |
5/15/2026
Event 3/31/2026
|
|
| EcoR1 Capital, LLC | 2.9% | ||
| Oleg Nodelman | 2.9% | ||
| EcoR1 Capital Fund Qualified, L.P. | 2.8% | ||
|
RA Capital Management, L.P.
13G
|
6.5% |
3/30/2026
Event 3/23/2026
|
|
| RA Capital Management, L.P. | 6.5% | ||
| Peter Kolchinsky | 6.5% | ||
| Rajeev Shah | 6.5% | ||
| RA Capital Healthcare Fund, L.P. | 6.5% | ||
| Vanguard Group Inc 13G/A Amendment 10 | 0% |
3/27/2026
Event 3/13/2026
|
|
|
EcoR1 Capital, LLC
13G/A
Amendment 5
|
6.4% |
2/17/2026
Event 12/31/2025
|
|
| EcoR1 Capital, LLC | 6.4% | ||
| Oleg Nodelman | 6.4% | ||
| EcoR1 Capital Fund Qualified, L.P. | 6.0% | ||
|
Biotechnology Value Fund L P
13G/A
Amendment 1
|
10.0% |
2/17/2026
Event 12/31/2025
|
|
| Biotechnology Value Fund L P | 5.3% | ||
| BVF I GP LLC | 5.3% | ||
| Biotechnology Value Fund II LP | 3.9% | ||
| BVF II GP LLC | 3.9% | ||
| Biotechnology Value Trading Fund OS LP | 0.6% | ||
| BVF Partners OS Ltd. | 0.6% | ||
| BVF GP Holdings LLC | 9.2% | ||
| BVF Partners L P/IL | 10.0% | ||
| BVF Inc/IL | 10.0% | ||
| Lampert Mark N | 10.0% | ||
| State Street Corp 13G | 6.3% |
2/9/2026
Event 12/31/2025
|
|
| Vanguard Group Inc 13G/A Amendment 9 | 10.0% |
12/3/2025
Event 11/28/2025
|
|
|
RTW Investments, LP
13G
|
8.7% |
11/14/2025
Event 9/30/2025
|
|
| RTW Investments, LP | 8.7% | ||
| Roderick Wong | 8.7% | ||
| Price T Rowe Associates Inc /MD/ 13G/A Amendment 12 | 2.4% |
11/14/2025
Event 9/30/2025
|
|
| Vanguard Group Inc 13G/A Amendment 8 | 10.0% |
10/31/2025
Event 9/30/2025
|
|
|
Biotechnology Value Fund L P
13G
|
6.5% |
10/17/2025
Event 10/9/2025
|
|
| Biotechnology Value Fund L P | 3.5% | ||
| BVF I GP LLC | 3.5% | ||
| Biotechnology Value Fund II LP | 2.5% | ||
| BVF II GP LLC | 2.5% | ||
| Biotechnology Value Trading Fund OS LP | 0.4% | ||
| BVF Partners OS Ltd. | 0.4% | ||
| BVF GP Holdings LLC | 6.0% | ||
| BVF Partners L P/IL | 6.5% | ||
| BVF Inc/IL | 6.5% | ||
| Lampert Mark N | 6.5% | ||
| Primecap Management Co/CA/ 13G/A Amendment 17 | 14.8% |
8/14/2025
Event 6/30/2025
|
|
| Vanguard Group Inc 13G/A Amendment 7 | 12.1% |
7/29/2025
Event 6/30/2025
|
|
| State Street Corp 13G | 5.2% |
5/13/2025
Event 3/31/2025
|
|
| BlackRock, Inc. 13G/A Amendment 6 | 15.8% |
4/29/2025
Event 3/31/2025
|
|
| BlackRock, Inc. 13G/A Amendment 5 | 17.4% |
2/5/2025
Event 12/31/2024
|
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 6 | 8.58 k | $214 k |
| 2026 Q2 | 210 | 84.9 M | $1.40 B |
| 2026 Q1 | 205 | 84.5 M | $1.02 B |
| 2025 Q4 | 211 | 81.9 M | $1.25 B |
| 2025 Q3 | 209 | 82.4 M | $965 M |
| 2025 Q2 | 197 | 83.6 M | $657 M |
| 2025 Q1 | 207 | 78.8 M | $838 M |
| 2024 Q4 | 198 | 75.0 M | $1.72 B |
| 2024 Q3 | 216 | 72.3 M | $1.45 B |
| 2024 Q2 | 207 | 65.9 M | $1.25 B |
| 2024 Q1 | 210 | 66.7 M | $1.48 B |
| 2023 Q4 | 204 | 65.1 M | $1.38 B |
| 2023 Q3 | 186 | 63.5 M | $1.28 B |
| 2023 Q2 | 188 | 62.7 M | $1.57 B |
| 2023 Q1 | 196 | 63.8 M | $1.79 B |
| 2022 Q4 | 205 | 64.7 M | $1.68 B |
| 2022 Q3 | 190 | 60.9 M | $1.58 B |
| 2022 Q2 | 178 | 59.8 M | $1.64 B |
| 2022 Q1 | 186 | 59.4 M | $1.58 B |
| 2021 Q4 | 183 | 59.3 M | $2.38 B |
| 2021 Q3 | 171 | 58.3 M | $1.90 B |
| 2021 Q2 | 180 | 58.0 M | $2.00 B |
| 2021 Q1 | 175 | 58.5 M | $2.52 B |
| 2020 Q4 | 185 | 60.0 M | $2.62 B |
| 2020 Q3 | 163 | 59.2 M | $2.30 B |
| 2020 Q2 | 165 | 58.6 M | $1.90 B |
| 2020 Q1 | 153 | 52.5 M | $1.57 B |
| 2019 Q4 | 170 | 54.2 M | $1.86 B |
| 2019 Q3 | 156 | 53.7 M | $1.81 B |
| 2019 Q2 | 126 | 49.0 M | $2.00 B |
| 2019 Q1 | 125 | 48.1 M | $1.49 B |
| 2018 Q4 | 121 | 48.4 M | $1.75 B |
| 2018 Q3 | 133 | 47.7 M | $1.86 B |
| 2018 Q2 | 125 | 46.9 M | $1.73 B |
| 2018 Q1 | 123 | 44.8 M | $1.34 B |
| 2017 Q4 | 105 | 37.4 M | $819 M |
| 2017 Q3 | 104 | 37.1 M | $851 M |
| 2017 Q2 | 115 | 36.8 M | $778 M |
| 2017 Q1 | 134 | 35.7 M | $854 M |
| 2016 Q4 | 140 | 35.1 M | $925 M |
| 2016 Q3 | 126 | 29.6 M | $725 M |
| 2016 Q2 | 105 | 28.3 M | $537 M |
| 2016 Q1 | 95 | 28.0 M | $376 M |
| 2015 Q4 | 98 | 26.3 M | $384 M |
| 2015 Q3 | 97 | 30.1 M | $368 M |
| 2015 Q2 | 97 | 25.3 M | $555 M |
| 2015 Q1 | 94 | 23.3 M | $357 M |
| 2014 Q4 | 63 | 14.1 M | $226 M |
| 2014 Q3 | 52 | 13.4 M | $125 M |
| 2014 Q2 | 53 | 13.6 M | $158 M |
| 2014 Q1 | 43 | 15.0 M | $176 M |