Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 87583X109 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Nextech Crossover I GP S.a r.l.
13G/A
Amendment 2
|
0% |
8/14/2026
Event 6/30/2026
|
|
| Nextech Crossover I GP S.a. r.l. | 0% | ||
| Nextech Crossover I SCSp | 0% | ||
| Ian Charoub | 0% | ||
| Costas Constantinides | 0% | ||
| Rocco Sgobbo | 0% | ||
|
TCG Crossover GP II, LLC
13G/A
Amendment 4
|
7.0% |
8/14/2026
Event 6/30/2026
|
|
| TCG Crossover GP II, LLC | 7.0% | ||
| TCG Crossover Fund II, L.P. | 7.0% | ||
| Chen Yu | 7.0% | ||
| Woodline Partners LP 13G/A Amendment 3 | 2.5% |
8/14/2026
Event 6/30/2026
|
|
|
Farallon Capital Management, L.L.C.
13G/A
Amendment 5
|
9.8% |
8/14/2026
Event 6/30/2026
|
|
| Farallon Capital Management, L.L.C. | 9.8% | ||
| Farallon Capital Partners, L.P. | 0% | ||
| Farallon Capital Institutional Partners, L.P. | 0% | ||
| Farallon Capital Institutional Partners II, L.P. | 0% | ||
| Farallon Capital Institutional Partners III, L.P. | 0% | ||
| Four Crossings Institutional Partners V, L.P. | 0% | ||
| Farallon Capital Offshore Investors II, L.P. | 0% | ||
| Farallon Capital (AM) Investors, L.P. | 0% | ||
| Farallon Capital F5 Master I, L.P. | 0% | ||
| Farallon Healthcare Partners Master, L.P. | 0% | ||
| Farallon Partners, L.L.C. | 0% | ||
| Farallon Institutional (GP) V, L.L.C. | 0% | ||
| Farallon F5 (GP), L.L.C. | 0% | ||
| Farallon Healthcare Partners (GP), L.L.C. | 0% | ||
| Dapice Joshua J. | 9.8% | ||
| Dreyfuss, Philip D. | 9.8% | ||
| Dunn Hannah E. | 9.8% | ||
| Gehani, Varun N. | 9.8% | ||
| Giauque, Nicolas | 9.8% | ||
| Husen, Avner A. | 9.8% | ||
| Kim, David T. | 9.8% | ||
| Linn, Michael G. | 9.8% | ||
| Luo Patrick (Cheng) | 9.8% | ||
| Roberts, Jr., Thomas G. | 9.8% | ||
| Saito Edric C. | 9.8% | ||
| Short Daniel S. | 9.8% | ||
| Spokes, Andrew J. M. | 9.8% | ||
| Warren, John R. | 9.8% | ||
| Wehrly, Mark C. | 9.8% | ||
|
Goldman Sachs Group Inc
13G
|
6.0% |
8/14/2026
Event 6/30/2026
|
|
| The Goldman Sachs Group, Inc. | 6.0% | ||
| Goldman Sachs & Co. LLC | 6.0% | ||
|
Adage Capital Management, L.P.
13G/A
Amendment 2
|
3.4% |
8/12/2026
Event 6/30/2026
|
|
| Adage Capital Management, L.P. | 3.4% | ||
| Robert Atchinson | 3.4% | ||
| Phillip Gross | 3.4% | ||
|
Nextech Crossover I GP S.a r.l.
13G/A
Amendment 1
|
5.1% |
5/15/2026
Event 3/31/2026
|
|
| Nextech Crossover I GP S.a. r.l. | 5.1% | ||
| Nextech Crossover I SCSp | 5.1% | ||
| Ian Charoub | 5.1% | ||
| Costas Constantinides | 5.1% | ||
| Rocco Sgobbo | 5.1% | ||
|
RTW Investments, LP
13G
|
9.3% |
5/15/2026
Event 3/31/2026
|
|
| RTW Investments, LP | 9.3% | ||
| Roderick Wong | 9.3% | ||
|
TCG Crossover GP II, LLC
13G/A
Amendment 3
|
8.1% |
5/15/2026
Event 3/31/2026
|
|
| TCG Crossover GP II, LLC | 8.1% | ||
| TCG Crossover Fund II, L.P. | 8.1% | ||
| Chen Yu | 8.1% | ||
| Woodline Partners LP 13G/A Amendment 2 | 5.6% |
5/15/2026
Event 3/31/2026
|
|
|
Adage Capital Management, L.P.
13G/A
Amendment 1
|
9.0% |
5/13/2026
Event 3/31/2026
|
|
| Adage Capital Management, L.P. | 9.0% | ||
| Robert Atchinson | 9.0% | ||
| Phillip Gross | 9.0% | ||
|
Farallon Capital Partners, L.P.
13G/A
Amendment 4
|
7.8% |
5/11/2026
Event 3/31/2026
|
|
| Farallon Capital Partners, L.P. | 0.7% | ||
| Farallon Capital Institutional Partners, L.P. | 1.0% | ||
| Farallon Capital Institutional Partners II, L.P. | 0.2% | ||
| Farallon Capital Institutional Partners III, L.P. | 0.2% | ||
| Four Crossings Institutional Partners V, L.P. | 0.2% | ||
| Farallon Capital Offshore Investors II, L.P. | 1.7% | ||
| Farallon Capital (AM) Investors, L.P. | 0.1% | ||
| Farallon Capital F5 Master I, L.P. | 0.2% | ||
| Farallon Healthcare Partners Master, L.P. | 3.5% | ||
| Farallon Partners, L.L.C. | 7.6% | ||
| Farallon Institutional (GP) V, L.L.C. | 0.2% | ||
| Farallon F5 (GP), L.L.C. | 0.2% | ||
| Farallon Healthcare Partners (GP), L.L.C. | 3.5% | ||
| Dapice Joshua J. | 7.8% | ||
| Dreyfuss, Philip D. | 7.8% | ||
| Dunn Hannah E. | 7.8% | ||
| Gehani, Varun N. | 7.8% | ||
| Giauque, Nicolas | 7.8% | ||
| Husen, Avner A. | 7.8% | ||
| Kim, David T. | 7.8% | ||
| Linn, Michael G. | 7.8% | ||
| Luo Patrick (Cheng) | 7.8% | ||
| Roberts, Jr., Thomas G. | 7.8% | ||
| Saito Edric C. | 7.8% | ||
| Short Daniel S. | 7.8% | ||
| Spokes, Andrew J. M. | 7.8% | ||
| Warren, John R. | 7.8% | ||
| Wehrly, Mark C. | 7.8% | ||
|
FMR LLC
13G
|
6.9% |
5/6/2026
Event 3/31/2026
|
|
| FMR LLC | 6.9% | ||
| Abigail P. Johnson | 6.9% | ||
|
Invus Global Management, LLC
13G/A
Amendment 2
|
4.0% |
5/4/2026
Event 3/31/2026
|
|
| Invus Public Equities, L.P. | 3.5% | ||
| Invus Public Equities Advisors, LLC | 3.5% | ||
| Invus Global Management, LLC | 3.5% | ||
| Siren, L.L.C. | 3.5% | ||
| Avicenna Life Sci Master Fund LP | 0.5% | ||
| Avicenna Life Sci Master GP LLC | 0.5% | ||
| Ulys, L.L.C. | 0.5% | ||
| Raymond Debbane | 4.0% | ||
| Vanguard Group Inc 13G/A Amendment 1 | 0% |
3/27/2026
Event 3/13/2026
|
|
|
TCG Crossover GP II, LLC
13G/A
Amendment 2
|
10.0% |
2/17/2026
Event 12/31/2025
|
|
| TCG Crossover GP II, L.P. | 10.0% | ||
| TCG Crossover Fund II, L.P. | 10.0% | ||
| Chen Yu | 10.0% | ||
|
EcoR1 Capital, LLC
13G/A
Amendment 3
|
0% |
2/17/2026
Event 12/31/2025
|
|
| EcoR1 Capital, LLC | 0% | ||
| Oleg Nodelman | 0% | ||
| EcoR1 Capital Fund Qualified, L.P. | 0% | ||
| Woodline Partners LP 13G/A Amendment 1 | 7.5% |
2/17/2026
Event 12/31/2025
|
|
|
Invus Global Management, LLC
13G/A
Amendment 1
|
6.1% |
2/13/2026
Event 12/31/2025
|
|
| Invus Public Equities, L.P. | 5.3% | ||
| Invus Public Equities Advisors, LLC | 5.3% | ||
| Invus Global Management, LLC | 5.3% | ||
| Siren, L.L.C. | 5.3% | ||
| Avicenna Life Sci Master Fund LP | 0.8% | ||
| Avicenna Life Sci Master GP LLC | 0.8% | ||
| Ulys, L.L.C. | 0.8% | ||
| Raymond Debbane | 6.1% | ||
|
Adage Capital Management, L.P.
13G
|
7.9% |
2/12/2026
Event 12/31/2025
|
|
| Adage Capital Management, L.P. | 7.9% | ||
| Robert Atchinson | 7.9% | ||
| Phillip Gross | 7.9% | ||
|
Third Rock Ventures IV, L.P.
13D/A
Amendment 4
|
4.7% |
2/10/2026
Event 2/6/2026
|
|
| Third Rock Ventures IV, L.P. | 4.7% | ||
| Third Rock Ventures GP IV, L.P. | 4.7% | ||
| TRV GP IV, LLC | 4.7% | ||
|
Farallon Partners L L C/CA
13G/A
Amendment 3
|
10.0% |
2/6/2026
Event 12/31/2025
|
|
| Farallon Capital Partners, L.P. | 1.6% | ||
| Farallon Capital Institutional Partners, L.P. | 2.2% | ||
| Farallon Capital Institutional Partners II, L.P. | 0.5% | ||
| Farallon Capital Institutional Partners III, L.P. | 0.4% | ||
| Four Crossings Institutional Partners V, L.P. | 0.4% | ||
| Farallon Capital Offshore Investors II, L.P. | 3.9% | ||
| Farallon Capital (AM) Investors, L.P. | 0.3% | ||
| Farallon Capital F5 Master I, L.P. | 0.4% | ||
| Farallon Healthcare Partners Master, L.P. | 0.2% | ||
| Farallon Partners, L.L.C. | 9.6% | ||
| Farallon Institutional (GP) V, L.L.C. | 0.4% | ||
| Farallon F5 (GP), L.L.C. | 0.4% | ||
| Farallon Healthcare Partners (GP), L.L.C. | 0.2% | ||
| Dapice Joshua J. | 10.0% | ||
| Dreyfuss, Philip D. | 10.0% | ||
| Dunn Hannah E. | 10.0% | ||
| Fried, Richard B | 0% | ||
| Gehani, Varun N. | 10.0% | ||
| Giauque, Nicolas | 10.0% | ||
| Husen, Avner A. | 10.0% | ||
| Kim, David T. | 10.0% | ||
| Linn, Michael G. | 10.0% | ||
| Luo Patrick (Cheng) | 10.0% | ||
| Patel, Rajiv A. | 0% | ||
| Roberts, Jr., Thomas G. | 10.0% | ||
| Saito Edric C. | 10.0% | ||
| Seybold, William | 0% | ||
| Short Daniel S. | 10.0% | ||
| Spokes, Andrew J. M. | 10.0% | ||
| Warren, John R. | 10.0% | ||
| Wehrly, Mark C. | 10.0% | ||
| Vanguard Group Inc 13G | 5.0% |
1/30/2026
Event 12/31/2025
|
|
| BlackRock, Inc. 13G | 6.3% |
1/21/2026
Event 12/31/2025
|
|
|
Third Rock Ventures IV, L.P.
13D/A
Amendment 3
|
5.9% |
11/21/2025
Event 11/19/2025
|
|
| Third Rock Ventures IV, L.P. | 5.9% | ||
| Third Rock Ventures GP IV, L.P. | 5.9% | ||
| TRV GP IV, LLC | 5.9% | ||
|
TCG Crossover GP II, LLC
13G/A
Amendment 1
|
6.3% |
11/14/2025
Event 9/30/2025
|
|
| TCG Crossover GP II, LLC | 6.3% | ||
| TCG Crossover Fund II, L.P. | 6.3% | ||
| Chen Yu | 6.3% | ||
|
Third Rock Ventures IV, L.P.
13D/A
Amendment 2
|
7.0% |
11/14/2025
Event 11/12/2025
|
|
| Third Rock Ventures IV, L.P. | 7.0% | ||
| Third Rock Ventures GP IV, L.P. | 7.0% | ||
| TRV GP IV, LLC | 7.0% | ||
|
Adage Capital Management, L.P.
13G/A
Amendment 1
|
2.3% |
11/13/2025
Event 9/30/2025
|
|
| Adage Capital Management, L.P. | 2.3% | ||
| Robert Atchinson | 2.3% | ||
| Phillip Gross | 2.3% | ||
|
Farallon Capital Partners, L.P.
13G/A
Amendment 2
|
9.7% |
11/12/2025
Event 9/30/2025
|
|
| Farallon Capital Partners, L.P. | 1.6% | ||
| Farallon Capital Institutional Partners, L.P. | 2.1% | ||
| Farallon Capital Institutional Partners II, L.P. | 0.5% | ||
| Farallon Capital Institutional Partners III, L.P. | 0.4% | ||
| Four Crossings Institutional Partners V, L.P. | 0.5% | ||
| Farallon Capital Offshore Investors II, L.P. | 4.0% | ||
| Farallon Capital F5 Master I, L.P. | 0.4% | ||
| Farallon Capital (AM) Investors, L.P. | 0.3% | ||
| Farallon Partners, L.L.C. | 9.3% | ||
| Farallon Institutional (GP) V, L.L.C. | 0.5% | ||
| Farallon F5 (GP), L.L.C. | 0.4% | ||
| Dapice Joshua J. | 9.7% | ||
| Dreyfuss, Philip D. | 9.7% | ||
| Dunn Hannah E. | 9.7% | ||
| Fried, Richard B | 9.7% | ||
| Gehani, Varun N. | 9.7% | ||
| Giauque, Nicolas | 9.7% | ||
| Kim, David T. | 9.7% | ||
| Linn, Michael G. | 9.7% | ||
| Luo Patrick (Cheng) | 9.7% | ||
| Patel, Rajiv A. | 9.7% | ||
| Roberts, Jr., Thomas G. | 9.7% | ||
| Saito Edric C. | 9.7% | ||
| Seybold, William | 9.7% | ||
| Short Daniel S. | 9.7% | ||
| Spokes, Andrew J. M. | 9.7% | ||
| Warren, John R. | 9.7% | ||
| Wehrly, Mark C. | 9.7% | ||
|
Invus Global Management, LLC
13G
|
5.3% |
9/22/2025
Event 9/19/2025
|
|
| Invus Public Equities, L.P. | 4.6% | ||
| Invus Public Equities Advisors, LLC | 4.6% | ||
| Invus Global Management, LLC | 4.6% | ||
| Siren, L.L.C. | 4.6% | ||
| Avicenna Life Sci Master Fund LP | 0.7% | ||
| Avicenna Life Sci Master GP LLC | 0.7% | ||
| Ulys, L.L.C. | 0.7% | ||
| Raymond Debbane | 5.3% | ||
| Woodline Partners LP 13G | 5.6% |
8/14/2025
Event 6/30/2025
|
|
|
Farallon Capital Partners, L.P.
13G/A
Amendment 1
|
8.4% |
8/13/2025
Event 6/30/2025
|
|
| Farallon Capital Partners, L.P. | 1.4% | ||
| Farallon Capital Institutional Partners, L.P. | 1.9% | ||
| Farallon Capital Institutional Partners II, L.P. | 0.5% | ||
| Farallon Capital Institutional Partners III, L.P. | 0.3% | ||
| Four Crossings Institutional Partners V, L.P. | 0.4% | ||
| Farallon Capital Offshore Investors II, L.P. | 3.5% | ||
| Farallon Capital F5 Master I, L.P. | 0.3% | ||
| Farallon Capital (AM) Investors, L.P. | 0.2% | ||
| Farallon Partners, L.L.C. | 8.1% | ||
| Farallon Institutional (GP) V, L.L.C. | 0.4% | ||
| Farallon F5 (GP), L.L.C. | 0.3% | ||
| Dapice Joshua J. | 8.4% | ||
| Dreyfuss, Philip D. | 8.4% | ||
| Dunn Hannah E. | 8.4% | ||
| Fried, Richard B | 8.4% | ||
| Gehani, Varun N. | 8.4% | ||
| Giauque, Nicolas | 8.4% | ||
| Kim, David T. | 8.4% | ||
| Linn, Michael G. | 8.4% | ||
| Luo Patrick (Cheng) | 8.4% | ||
| Patel, Rajiv A. | 8.4% | ||
| Roberts, Jr., Thomas G. | 8.4% | ||
| Saito Edric C. | 8.4% | ||
| Seybold, William | 8.4% | ||
| Short Daniel S. | 8.4% | ||
| Spokes, Andrew J. M. | 8.4% | ||
| Warren, John R. | 8.4% | ||
| Wehrly, Mark C. | 8.4% | ||
|
Adage Capital Management, L.P.
13G
|
5.5% |
8/12/2025
Event 6/30/2025
|
|
| Adage Capital Management, L.P. | 5.5% | ||
| Robert Atchinson | 5.5% | ||
| Phillip Gross | 5.5% | ||
| BlackRock, Inc. 13G |
5.0%
Checked 5% or less
|
7/17/2025
Event 6/30/2025
|
|
|
Farallon Capital Partners, L.P.
13G
|
6.6% |
6/13/2025
Event 6/6/2025
|
|
| Farallon Capital Partners, L.P. | 1.1% | ||
| Farallon Capital Institutional Partners, L.P. | 1.5% | ||
| Farallon Capital Institutional Partners II, L.P. | 0.3% | ||
| Farallon Capital Institutional Partners III, L.P. | 0.2% | ||
| Four Crossings Institutional Partners V, L.P. | 0.3% | ||
| Farallon Capital Offshore Investors II, L.P. | 2.8% | ||
| Farallon Capital F5 Master I, L.P. | 0.3% | ||
| Farallon Capital (AM) Investors, L.P. | 0.2% | ||
| Farallon Partners, L.L.C. | 6.4% | ||
| Farallon Institutional (GP) V, L.L.C. | 0.3% | ||
| Farallon F5 (GP), L.L.C. | 0.3% | ||
| Dapice Joshua J. | 6.6% | ||
| Dreyfuss, Philip D. | 6.6% | ||
| Dunn Hannah E. | 6.6% | ||
| Fried, Richard B | 6.6% | ||
| Gehani, Varun N. | 6.6% | ||
| Giauque, Nicolas | 6.6% | ||
| Kim, David T. | 6.6% | ||
| Linn, Michael G. | 6.6% | ||
| Luo Patrick (Cheng) | 6.6% | ||
| Patel, Rajiv A. | 6.6% | ||
| Roberts, Jr., Thomas G. | 6.6% | ||
| Saito Edric C. | 6.6% | ||
| Seybold, William | 6.6% | ||
| Short Daniel S. | 6.6% | ||
| Spokes, Andrew J. M. | 6.6% | ||
| Warren, John R. | 6.6% | ||
| Wehrly, Mark C. | 6.6% | ||
|
EcoR1 Capital, LLC
13G/A
Amendment 2
|
9.9% |
2/14/2025
Event 12/31/2024
|
|
| EcoR1 Capital, LLC | 9.9% | ||
| Oleg Nodelman | 9.9% | ||
| EcoR1 Capital Fund Qualified, L.P. | 9.3% | ||
|
BCTG Holdings, LLC
13D/A
Amendment 7
|
10.0% |
1/2/2025
Event 12/30/2024
|
|
| BCTG Holdings, LLC | 0% | ||
| MVA Investors, LLC | 0.3% | ||
| Davis Aaron I. | 10.0% | ||
| Boxer Capital Management, LLC | 9.7% | ||
|
FMR LLC
13G/A
Amendment 4
|
0% |
12/6/2024
Event 11/29/2024
|
|
| FMR LLC | 0% | ||
| Abigail P. Johnson | 0% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 10 | 1.20 M | $30.0 M |
| 2026 Q2 | 260 | 218 M | $6.73 B |
| 2026 Q1 | 201 | 180 M | $3.78 B |
| 2025 Q4 | 177 | 173 M | $1.53 B |
| 2025 Q3 | 148 | 140 M | $1.18 B |
| 2025 Q2 | 121 | 127 M | $653 M |
| 2025 Q1 | 125 | 107 M | $147 M |
| 2024 Q4 | 141 | 106 M | $329 M |
| 2024 Q3 | 125 | 102 M | $782 M |
| 2024 Q2 | 126 | 98.9 M | $849 M |
| 2024 Q1 | 134 | 98.9 M | $785 M |
| 2023 Q4 | 127 | 94.3 M | $934 M |
| 2023 Q3 | 101 | 88.8 M | $1.00 B |
| 2023 Q2 | 90 | 68.3 M | $227 M |
| 2023 Q1 | 95 | 69.9 M | $276 M |
| 2022 Q4 | 85 | 69.6 M | $505 M |
| 2022 Q3 | 90 | 68.2 M | $247 M |
| 2022 Q2 | 78 | 70.5 M | $319 M |
| 2022 Q1 | 73 | 69.7 M | $528 M |
| 2021 Q4 | 60 | 67.9 M | $742 M |
| 2021 Q3 | 47 | 65.5 M | $845 M |