Investors who own more than 5% of a class must file a Schedule 13D or 13G. Each filer's latest filing for 83422E204 since 12/18/2024, largest first.
| Filer | % of Class | Filed | ||
|---|---|---|---|---|
|
RA Capital Management, L.P.
13D/A
|
11.9% |
6/24/2026
Event 6/22/2026
|
||
| RA Capital Management, L.P. | 11.9% | |||
| Peter Kolchinsky | 11.9% | |||
| Rajeev Shah | 11.9% | |||
| RA Capital Healthcare Fund, L.P. | 11.8% | |||
|
Perceptive Advisors LLC
13D/A
|
11.2% |
8/14/2026
Event 6/30/2026
|
||
| Perceptive Advisors LLC | 11.2% | |||
| Joseph Edelman | 11.2% | |||
| Perceptive Life Sciences Master Fund, Ltd. | 11.2% | |||
| Perceptive Xontogeny Venture Fund, LP | 0.1% | |||
|
Invus Global Management, LLC
13G/A
|
10.0% |
5/5/2026
Event 3/31/2026
|
||
| Invus Public Equities, L.P. | 8.7% | |||
| Invus Public Equities Advisors, LLC | 8.7% | |||
| Invus Global Management, LLC | 8.7% | |||
| Siren, L.L.C. | 8.7% | |||
| Avicenna Life Sci Master Fund LP | 1.4% | |||
| Avicenna Life Sci Master GP LLC | 1.4% | |||
| Ulys, L.L.C. | 1.4% | |||
| Raymond Debbane | 10.0% | |||
|
FMR LLC
13G
|
7.0% |
8/6/2026
Event 6/30/2026
|
||
| FMR LLC | 7.0% | |||
| Abigail P. Johnson | 7.0% | |||
| BlackRock, Inc. 13G | 6.5% |
7/30/2026
Event 6/30/2026
|
||
| Under 5%, checked the "5 percent or less" box, or amended by a later filing (3) | ||||
|
Vestal Point Capital, LP
13G/A
|
4.8% |
8/14/2026
Event 6/30/2026
|
||
| Vestal Point Capital, LP | 4.8% | |||
| Ryan Wilder | 4.8% | |||
|
Adage Capital Management, L.P.
13G/A
|
1.8% |
2/12/2026
Event 12/31/2025
|
||
| Adage Capital Management, L.P. | 1.8% | |||
| Robert Atchinson | 1.8% | |||
| Phillip Gross | 1.8% | |||
|
Commodore Capital LP
13G/A
|
0% |
8/14/2025
Event 6/30/2025
|
||
| Commodore Capital LP | 0% | |||
| Commodore Capital Master LP | 0% | |||
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 4 | 8.35 k | $60.4 k |
| 2026 Q2 | 162 | 115 M | $1.15 B |
| 2026 Q1 | 152 | 99.9 M | $719 M |
| 2025 Q4 | 131 | 81.4 M | $459 M |
| 2025 Q3 | 130 | 81.4 M | $502 M |
| 2025 Q2 | 116 | 82.6 M | $402 M |
| 2025 Q1 | 127 | 78.8 M | $292 M |
| 2024 Q4 | 98 | 36.3 M | $145 M |
| 2024 Q3 | 101 | 35.9 M | $250 M |
| 2024 Q2 | 85 | 37.7 M | $214 M |
| 2024 Q1 | 61 | 35.1 M | $467 M |
| 2023 Q4 | 42 | 16.6 M | $102 M |
| 2023 Q3 | 37 | 16.2 M | $40.7 M |
| 2023 Q2 | 35 | 16.3 M | $85.6 M |
| 2023 Q1 | 40 | 15.8 M | $74.8 M |
| 2022 Q4 | 37 | 15.3 M | $85.7 M |
| 2020 Q3 | 1 | 307 k | $623 k |