Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 45773H409 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Adage Capital Management, L.P.
13G/A
Amendment 2
|
4.0% |
8/12/2026
Event 6/30/2026
|
|
| Adage Capital Management, L.P. | 4.0% | ||
| Robert Atchinson | 4.0% | ||
| Phillip Gross | 4.0% | ||
|
RA Capital Management, L.P.
13G
|
9.9% |
8/7/2026
Event 7/31/2026
|
|
| RA Capital Management, L.P. | 9.9% | ||
| Peter Kolchinsky | 9.9% | ||
| Rajeev Shah | 9.9% | ||
| RA Capital Healthcare Fund, L.P. | 9.9% | ||
|
FMR LLC
13G/A
Amendment 2
|
10.3% |
8/6/2026
Event 6/30/2026
|
|
| FMR LLC | 10.3% | ||
| Abigail P. Johnson | 10.3% | ||
| Vanguard Capital Management LLC 13G | 5.1% |
7/31/2026
Event 6/30/2026
|
|
| Highbridge Capital Management LLC 13G/A Amendment 1 | 8.2% |
5/15/2026
Event 3/31/2026
|
|
|
Adage Capital Management, L.P.
13G/A
Amendment 1
|
5.8% |
5/13/2026
Event 3/31/2026
|
|
| Adage Capital Management, L.P. | 5.8% | ||
| Robert Atchinson | 5.8% | ||
| Phillip Gross | 5.8% | ||
|
FMR LLC
13G/A
Amendment 1
|
13.5% |
5/6/2026
Event 3/31/2026
|
|
| FMR LLC | 13.5% | ||
| Abigail P. Johnson | 13.5% | ||
|
Alyeska Investment Group, L.P.
13G/A
Amendment 1
|
6.0% |
2/17/2026
Event 12/31/2025
|
|
| Alyeska Investment Group, L.P. | 6.0% | ||
| Alyeska Fund GP, LLC | 6.0% | ||
| Anand Parekh | 6.0% | ||
| Vanguard Group Inc 13G/A Amendment 1 | 4.96% |
1/30/2026
Event 12/31/2025
|
|
| Janus Henderson Group PLC 13G/A Amendment 1 | 10.0% |
12/8/2025
Event 11/28/2025
|
|
|
FMR LLC
13G
|
14.8% |
12/5/2025
Event 11/28/2025
|
|
| FMR LLC | 14.8% | ||
| Abigail P. Johnson | 14.8% | ||
|
Janus Henderson Group PLC
13G
|
6.2% |
11/14/2025
Event 9/30/2025
|
|
| Janus Henderson Group PLC | 6.2% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.3% | ||
|
Alyeska Investment Group, L.P.
13G
|
7.5% |
11/14/2025
Event 9/30/2025
|
|
| Alyeska Investment Group, L.P. | 7.5% | ||
| Alyeska Fund GP, LLC | 7.5% | ||
| Anand Parekh | 7.5% | ||
|
Deep Track Capital, LP
13G/A
Amendment 1
|
2.4% |
11/14/2025
Event 9/30/2025
|
|
| Deep Track Capital, LP | 2.4% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 2.4% | ||
| David Kroin | 2.4% | ||
|
Adage Capital Management, L.P.
13G
|
10.0% |
11/13/2025
Event 9/30/2025
|
|
| Adage Capital Management, L.P. | 10.0% | ||
| Robert Atchinson | 10.0% | ||
| Phillip Gross | 10.0% | ||
| BlackRock, Inc. 13G/A Amendment 3 | 1.5% |
7/17/2025
Event 6/30/2025
|
|
|
Stonepine Capital Management, LLC
13G/A
Amendment 1
|
3.8% |
5/14/2025
Event 3/31/2025
|
|
| Stonepine Capital Management, LLC | 3.8% | ||
| Stonepine Capital, L.P. | 3.8% | ||
| Stonepine GP, LLC | 3.8% | ||
| Jon M. Plexico | 3.8% | ||
| Vanguard Group Inc 13G | 5.5% |
4/30/2025
Event 3/31/2025
|
|
| BlackRock, Inc. 13G/A Amendment 2 | 6.3% |
4/17/2025
Event 3/31/2025
|
|
| Highbridge Capital Management, LLC 13G | 9.2% |
2/10/2025
Event 12/31/2024
|
|
| BlackRock, Inc. 13G/A Amendment 1 | 5.3% |
2/5/2025
Event 12/31/2024
|
|
| Vanguard Group Inc 13G/A Amendment 5 | 4.6% |
1/30/2025
Event 12/31/2024
|
|
|
Stonepine Capital Management, LLC
13G
|
5.2% |
12/23/2024
Event 12/17/2024
|
|
| Stonepine Capital Management, LLC | 5.2% | ||
| Stonepine Capital, L.P. | 5.2% | ||
| Stonepine GP, LLC | 5.2% | ||
| Jon M. Plexico | 5.2% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 4 | 115 k | $140 k |
| 2026 Q2 | 111 | 32.8 M | $36.1 M |
| 2026 Q1 | 107 | 31.4 M | $54.6 M |
| 2025 Q4 | 110 | 33.1 M | $57.5 M |
| 2025 Q3 | 106 | 20.8 M | $48.6 M |
| 2025 Q2 | 111 | 10.3 M | $20.9 M |
| 2025 Q1 | 112 | 13.6 M | $22.2 M |
| 2024 Q4 | 113 | 13.4 M | $24.5 M |
| 2024 Q3 | 107 | 8.58 M | $49.5 M |
| 2024 Q2 | 106 | 8.17 M | $66.0 M |
| 2024 Q1 | 96 | 4.20 M | $58.2 M |
| 2023 Q4 | 7 | 299 k | $153 k |