Investors who own more than 5% of a class must file a Schedule 13D or 13G. Each filer's latest filing for 450056106 since 12/18/2024, largest first.
| Filer | % of Class | Filed | ||
|---|---|---|---|---|
|
RTW Investments, LP
13G/A
|
6.6% |
8/14/2026
Event 6/30/2026
|
||
| RTW Investments, LP | 6.6% | |||
| Roderick Wong | 6.6% | |||
| Vanguard Portfolio Management LLC 13G | 5.6% |
4/28/2026
Event 3/31/2026
|
||
| Vanguard Capital Management LLC 13G | 5.2% |
4/27/2026
Event 3/31/2026
|
||
|
Millennium Management LLC
13G
|
5.1% |
3/23/2026
Event 3/16/2026
|
||
| Millennium Management LLC | 5.1% | |||
| Millennium Group Management LLC | 5.1% | |||
| Israel A. Englander | 5.1% | |||
|
Artisan Partners Limited Partnership
13G
|
5.1% |
8/13/2026
Event 6/30/2026
|
||
| Artisan Partners Asset Management Inc. | 5.1% | |||
| Artisan Partners Holdings LP | 5.1% | |||
| Artisan Investments GP LLC | 5.1% | |||
| Artisan Partners Limited Partnership | 5.1% | |||
| Under 5%, checked the "5 percent or less" box, or amended by a later filing (3) | ||||
| Capital Research Global Investors 13G/A | 4.7% |
8/13/2025
Event 6/30/2025
|
||
|
Sands Capital Management, LLC
13G/A
|
0% |
5/8/2026
Event 3/31/2026
|
||
| Sands Capital Management, LLC | 0% | |||
| Sands Frank M. | 0% | |||
| Vanguard Group Inc 13G/A | 0% |
3/26/2026
Event 3/13/2026
|
||
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 7 | 12.7 k | $1.44 M |
| 2026 Q2 | 319 | 40.9 M | $4.29 B |
| 2026 Q1 | 317 | 35.5 M | $4.19 B |
| 2025 Q4 | 348 | 35.8 M | $6.36 B |
| 2025 Q3 | 354 | 35.2 M | $6.05 B |
| 2025 Q2 | 324 | 35.7 M | $5.49 B |
| 2025 Q1 | 271 | 36.0 M | $3.77 B |
| 2024 Q4 | 249 | 37.1 M | $3.26 B |
| 2024 Q3 | 268 | 35.2 M | $2.61 B |
| 2024 Q2 | 248 | 36.9 M | $3.97 B |
| 2024 Q1 | 277 | 36.1 M | $4.19 B |
| 2023 Q4 | 245 | 34.8 M | $3.72 B |
| 2023 Q3 | 251 | 32.6 M | $3.07 B |
| 2023 Q2 | 223 | 33.6 M | $3.50 B |
| 2023 Q1 | 231 | 33.9 M | $4.21 B |
| 2022 Q4 | 226 | 32.0 M | $3.00 B |
| 2022 Q3 | 255 | 31.0 M | $3.87 B |
| 2022 Q2 | 260 | 30.4 M | $3.29 B |
| 2022 Q1 | 237 | 30.5 M | $4.80 B |
| 2021 Q4 | 231 | 29.2 M | $3.43 B |
| 2021 Q3 | 208 | 28.1 M | $1.64 B |
| 2021 Q2 | 200 | 29.1 M | $1.93 B |
| 2021 Q1 | 237 | 31.3 M | $4.33 B |
| 2020 Q4 | 264 | 36.5 M | $8.63 B |
| 2020 Q3 | 253 | 31.3 M | $7.43 B |
| 2020 Q2 | 214 | 30.9 M | $3.58 B |
| 2020 Q1 | 182 | 32.7 M | $2.65 B |
| 2019 Q4 | 182 | 33.2 M | $2.26 B |
| 2019 Q3 | 181 | 31.4 M | $2.32 B |
| 2019 Q2 | 190 | 30.6 M | $2.41 B |
| 2019 Q1 | 193 | 27.6 M | $2.07 B |
| 2018 Q4 | 171 | 25.9 M | $1.80 B |
| 2018 Q3 | 178 | 25.5 M | $2.42 B |
| 2018 Q2 | 151 | 24.9 M | $2.02 B |
| 2018 Q1 | 147 | 24.3 M | $1.53 B |
| 2017 Q4 | 124 | 23.1 M | $1.30 B |
| 2017 Q3 | 109 | 22.5 M | $1.17 B |
| 2017 Q2 | 101 | 21.2 M | $900 M |
| 2017 Q1 | 65 | 13.1 M | $494 M |
| 2016 Q4 | 67 | 10.6 M | $318 M |