Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 359616109 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
RA Capital Management, L.P.
13G/A
Amendment 7
|
0% |
8/14/2026
Event 6/30/2026
|
|
| RA Capital Management, L.P. | 0% | ||
| Peter Kolchinsky | 0% | ||
| Rajeev Shah | 0% | ||
| RA Capital Healthcare Fund, L.P. | 0% | ||
|
TCG Crossover GP II, LLC
13G/A
Amendment 2
|
0% |
8/14/2026
Event 6/30/2026
|
|
| TCG Crossover GP II, LLC | 0% | ||
| TCG Crossover Fund II, L.P. | 0% | ||
| Chen Yu | 0% | ||
|
Nantahala Capital Management, LLC
13G
|
8.2% |
8/14/2026
Event 6/30/2026
|
|
| Nantahala Capital Management, LLC | 8.2% | ||
| Wilmot B. Harkey | 8.2% | ||
| Daniel Mack | 8.2% | ||
|
Montanova Capital, LLC
13G/A
Amendment 2
|
5.5% |
8/14/2026
Event 6/30/2026
|
|
| Montanova Capital, LLC | 5.5% | ||
| Averill Master Fund, Ltd. | 3.8% | ||
| Aaron Cowen | 5.5% | ||
| Bank of America Corp /DE/ 13G | 6.7% |
8/3/2026
Event 6/30/2026
|
|
| BlackRock, Inc. 13G/A Amendment 4 | 7.2% |
7/28/2026
Event 6/30/2026
|
|
| BlackRock Portfolio Management LLC 13G | 6.0% |
7/17/2026
Event 6/30/2026
|
|
|
Tang Capital Management LLC
13G/A
Amendment 1
|
10.4% |
7/15/2026
Event 7/13/2026
|
|
| Tang Capital Management, LLC | 10.4% | ||
| Kevin Tang | 10.4% | ||
| Tang Capital Partners, LP | 2.5% | ||
| Tang Capital Partners International, LP | 3.2% | ||
| Tang Capital Partners III, Inc | 2.5% | ||
| Tang Capital Partners IV, Inc | 2.2% | ||
|
EcoR1 Capital, LLC
13G
|
9.0% |
6/25/2026
Event 6/17/2026
|
|
| EcoR1 Capital, LLC | 9.0% | ||
| Oleg Nodelman | 9.0% | ||
| EcoR1 Capital Fund Qualified, L.P. | 8.4% | ||
|
EcoR1 Capital, LLC
13G
|
9.0% |
6/25/2026
Event 6/17/2026
|
|
| EcoR1 Capital, LLC | 9.0% | ||
| Oleg Nodelman | 9.0% | ||
| EcoR1 Capital Fund Qualified, L.P. | 8.4% | ||
|
Tang Capital Management LLC
13G
|
8.2% |
6/10/2026
Event 6/3/2026
|
|
| Tang Capital Management, LLC | 8.2% | ||
| Kevin Tang | 8.2% | ||
| Tang Capital Partners, LP | 1.9% | ||
| Tang Capital Partners International, LP | 2.5% | ||
| Tang Capital Partners III, Inc | 1.9% | ||
| Tang Capital Partners IV, Inc | 1.9% | ||
|
TCG Crossover GP II, LLC
13G/A
Amendment 1
|
7.9% |
5/15/2026
Event 3/31/2026
|
|
| TCG Crossover GP II, LLC | 7.9% | ||
| TCG Crossover Fund II, L.P. | 7.9% | ||
| Chen Yu | 7.9% | ||
|
Nantahala Capital Management, LLC
13G/A
Amendment 1
|
4.6% |
5/15/2026
Event 3/31/2026
|
|
| Nantahala Capital Management, LLC | 4.6% | ||
| Wilmot B. Harkey | 4.6% | ||
| Daniel Mack | 4.6% | ||
| Vanguard Group Inc 13G/A Amendment 2 | 0% |
3/26/2026
Event 3/13/2026
|
|
|
RA Capital Management, L.P.
13G/A
Amendment 6
|
9.9% |
2/17/2026
Event 12/31/2025
|
|
| RA Capital Management, L.P. | 9.9% | ||
| Peter Kolchinsky | 9.9% | ||
| Rajeev Shah | 9.9% | ||
| RA Capital Healthcare Fund, L.P. | 9.9% | ||
|
RA Capital Management, L.P.
13G/A
Amendment 5
|
11.2% |
12/10/2025
Event 12/8/2025
|
|
| RA Capital Management, L.P. | 11.2% | ||
| Peter Kolchinsky | 11.2% | ||
| Rajeev Shah | 11.2% | ||
| RA Capital Healthcare Fund, L.P. | 11.2% | ||
|
Adage Capital Management, L.P.
13G/A
Amendment 2
|
4.5% |
11/13/2025
Event 9/30/2025
|
|
| Adage Capital Management, L.P. | 4.5% | ||
| Robert Atchinson | 4.5% | ||
| Phillip Gross | 4.5% | ||
| BlackRock, Inc. 13G/A Amendment 3 | 6.0% |
10/17/2025
Event 9/30/2025
|
|
|
Adage Capital Management, L.P.
13G/A
Amendment 1
|
8.5% |
8/12/2025
Event 6/30/2025
|
|
| Adage Capital Management, L.P. | 8.5% | ||
| Robert Atchinson | 8.5% | ||
| Phillip Gross | 8.5% | ||
|
Suvretta Capital Management, LLC
13G/A
Amendment 1
|
9.4% |
5/2/2025
Event 3/31/2025
|
|
| Suvretta Capital Management, LLC | 9.4% | ||
| Averill Master Fund, Ltd. | 8.6% | ||
| Aaron Cowen | 9.4% | ||
| BlackRock, Inc. 13G/A Amendment 2 | 7.5% |
4/17/2025
Event 3/31/2025
|
|
|
Adage Capital Management, L.P.
13G
|
5.6% |
2/12/2025
Event 12/31/2024
|
|
| Adage Capital Management, L.P. | 5.6% | ||
| Robert Atchinson | 5.6% | ||
| Phillip Gross | 5.6% | ||
|
Suvretta Capital Management, LLC
13G
|
6.3% |
1/6/2025
Event 12/27/2024
|
|
| Suvretta Capital Management, LLC | 6.3% | ||
| Averill Master Fund, Ltd. | 5.8% | ||
| Aaron Cowen | 6.3% | ||
|
Nantahala Capital Management, LLC
13G
|
7.7% |
11/14/2024
Event 9/30/2024
|
|
| Nantahala Capital Management, LLC | 7.7% | ||
| Wilmot B. Harkey | 7.7% | ||
| Daniel Mack | 7.7% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 4 | 22.5 k | $83.1 k |
| 2026 Q2 | 165 | 85.8 M | $315 M |
| 2026 Q1 | 176 | 71.7 M | $550 M |
| 2025 Q4 | 182 | 67.6 M | $764 M |
| 2025 Q3 | 135 | 53.8 M | $496 M |
| 2025 Q2 | 132 | 55.6 M | $383 M |
| 2025 Q1 | 122 | 51.4 M | $148 M |
| 2024 Q4 | 133 | 52.0 M | $244 M |
| 2024 Q3 | 155 | 55.1 M | $197 M |
| 2024 Q2 | 140 | 66.1 M | $410 M |
| 2024 Q1 | 141 | 62.9 M | $593 M |
| 2023 Q4 | 110 | 63.2 M | $427 M |
| 2023 Q3 | 88 | 56.6 M | $251 M |
| 2023 Q2 | 94 | 55.5 M | $183 M |
| 2023 Q1 | 123 | 60.4 M | $172 M |
| 2022 Q4 | 118 | 51.5 M | $374 M |
| 2022 Q3 | 114 | 52.2 M | $422 M |
| 2022 Q2 | 113 | 40.1 M | $197 M |
| 2022 Q1 | 116 | 39.5 M | $930 M |
| 2021 Q4 | 123 | 37.5 M | $662 M |
| 2021 Q3 | 111 | 36.6 M | $1.03 B |
| 2021 Q2 | 69 | 27.1 M | $284 M |
| 2021 Q1 | 69 | 26.9 M | $317 M |
| 2020 Q4 | 67 | 22.2 M | $260 M |
| 2020 Q3 | 56 | 20.6 M | $163 M |
| 2020 Q2 | 62 | 20.5 M | $374 M |
| 2020 Q1 | 50 | 16.8 M | $201 M |
| 2019 Q4 | 40 | 15.8 M | $263 M |
| 2019 Q3 | 41 | 16.8 M | $110 M |