Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 34962G208 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Federated Hermes, Inc.
13G/A
Amendment 4
|
0% |
9/8/2026
Event 8/31/2026
|
|
| Federated Hermes, Inc. | 0% | ||
| Voting Shares Irrevocable Trust | 0% | ||
| Thomas R. Donahue | 0% | ||
| Ann C. Donahue | 0% | ||
| J. Christopher Donahue | 0% | ||
|
Orbimed Advisors LLC
13G/A
Amendment 2
|
6.2% |
8/14/2026
Event 6/30/2026
|
|
| Orbimed Advisors LLC | 6.2% | ||
| OrbiMed Capital GP IX LLC | 5.1% | ||
| Orbimed Capital LLC | 1.5% | ||
| Janus Henderson Group Ltd. 13G/A Amendment 5 | 9.3% |
8/13/2026
Event 6/30/2026
|
|
|
Affinity Asset Advisors, LLC
13G/A
Amendment 3
|
5.6% |
8/13/2026
Event 6/30/2026
|
|
| Affinity Asset Advisors, LLC | 5.6% | ||
| Michael Cho | 5.6% | ||
|
Adage Capital Management, L.P.
13G/A
Amendment 1
|
3.4% |
8/12/2026
Event 6/30/2026
|
|
| Adage Capital Management, L.P. | 3.4% | ||
| Robert Atchinson | 3.4% | ||
| Phillip Gross | 3.4% | ||
|
Glazer Capital, LLC
13G
|
1.5% |
8/11/2026
Event 8/4/2026
|
|
| Glazer Capital, LLC | 1.5% | ||
| Paul J. Glazer | 1.5% | ||
| Janus Henderson Group Ltd. 13G/A Amendment 6 | 2.5% |
8/7/2026
Event 7/31/2026
|
|
| Alger Associates, Inc. 13G/A Amendment 9 | 4.6% |
8/7/2026
Event 7/31/2026
|
|
| BlackRock, Inc. 13G | 5.9% |
7/28/2026
Event 6/30/2026
|
|
|
Millennium Management LLC
13G/A
Amendment 1
|
3.2% |
7/16/2026
Event 6/30/2026
|
|
| Millennium Management LLC | 3.2% | ||
| Millennium Group Management LLC | 3.2% | ||
| Israel A. Englander | 3.2% | ||
|
Federated Hermes, Inc.
13G/A
Amendment 3
|
10.3% |
7/8/2026
Event 6/30/2026
|
|
| Federated Hermes, Inc. | 10.3% | ||
| Voting Shares Irrevocable Trust | 10.3% | ||
| Thomas R. Donahue | 10.3% | ||
| Ann C. Donahue | 10.3% | ||
| J. Christopher Donahue | 10.3% | ||
|
Millennium Management LLC
13G
|
5.2% |
6/8/2026
Event 6/4/2026
|
|
| Millennium Management LLC | 5.2% | ||
| Millennium Group Management LLC | 5.2% | ||
| Israel A. Englander | 5.2% | ||
| MPM BioImpact LLC 13G | 7.2% |
5/15/2026
Event 3/31/2026
|
|
| Janus Henderson Group PLC 13G/A Amendment 4 | 10.0% |
5/15/2026
Event 3/31/2026
|
|
| Alger Associates, Inc. 13G/A Amendment 8 | 10.2% |
5/15/2026
Event 3/31/2026
|
|
|
Orbimed Advisors LLC
13G/A
Amendment 1
|
4.3% |
5/15/2026
Event 3/31/2026
|
|
| Orbimed Advisors LLC | 4.3% | ||
| Orbimed Capital LLC | 1.5% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 1
|
0% |
5/15/2026
Event 3/31/2026
|
|
| Point72 Asset Management, L.P. | 0% | ||
| Point72 Capital Advisors, Inc. | 0% | ||
| Steven A. Cohen | 0% | ||
|
Affinity Asset Advisors, LLC
13G/A
Amendment 2
|
7.3% |
5/14/2026
Event 3/31/2026
|
|
| Affinity Asset Advisors, LLC | 7.3% | ||
| Michael Cho | 7.3% | ||
|
Adage Capital Management, L.P.
13G
|
6.8% |
5/13/2026
Event 3/31/2026
|
|
| Adage Capital Management, L.P. | 6.8% | ||
| Robert Atchinson | 6.8% | ||
| Phillip Gross | 6.8% | ||
| Janus Henderson Group PLC 13G/A Amendment 3 | 11.4% |
2/17/2026
Event 12/31/2025
|
|
|
Affinity Asset Advisors, LLC
13G/A
Amendment 1
|
6.7% |
1/29/2026
Event 1/22/2026
|
|
| Affinity Asset Advisors, LLC | 6.7% | ||
| Michael Cho | 6.7% | ||
|
Point72 Asset Management, L.P.
13G
|
6.3% |
1/20/2026
Event 1/12/2026
|
|
| Point72 Asset Management, L.P. | 6.3% | ||
| Point72 Capital Advisors, Inc. | 6.3% | ||
| Steven A. Cohen | 6.3% | ||
|
Oliveira Steven Michael
13G/A
Amendment 1
|
2.4% |
1/9/2026
Event 1/8/2026
|
|
| Oliveira Steven Michael | 2.4% | ||
| Nemean Asset Management, LLC | 2.4% | ||
|
Affinity Asset Advisors, LLC
13G
|
6.9% |
12/23/2025
Event 12/17/2025
|
|
| Affinity Asset Advisors, LLC | 6.9% | ||
| Affinity Healthcare Fund, LP | 6.9% | ||
| Alger Associates, Inc. 13G/A Amendment 7 | 13.1% |
11/14/2025
Event 9/30/2025
|
|
|
Biotechnology Value Fund L P
13G/A
Amendment 2
|
0.5% |
11/14/2025
Event 9/30/2025
|
|
| Biotechnology Value Fund L P | 0.3% | ||
| BVF I GP LLC | 0.3% | ||
| Biotechnology Value Fund II LP | 0.2% | ||
| BVF II GP LLC | 0.2% | ||
| Biotechnology Value Trading Fund OS LP | <0.1% | ||
| BVF Partners OS Ltd. | <0.1% | ||
| BVF GP Holdings LLC | 0.5% | ||
| BVF Partners L P/IL | 0.5% | ||
| BVF Inc/IL | 0.5% | ||
| Lampert Mark N | 0.5% | ||
|
Federated Hermes, Inc.
13G/A
Amendment 2
|
13.2% |
10/7/2025
Event 9/30/2025
|
|
| Federated Hermes, Inc. | 13.2% | ||
| Voting Shares Irrevocable Trust | 13.2% | ||
| Thomas R. Donahue | 13.2% | ||
| Ann C. Donahue | 13.2% | ||
| J. Christopher Donahue | 13.2% | ||
|
Federated Hermes, Inc.
13G/A
Amendment 1
|
11.9% |
9/5/2025
Event 8/31/2025
|
|
| Federated Hermes, Inc. | 11.9% | ||
| Voting Shares Irrevocable Trust | 11.9% | ||
| Thomas R. Donahue | 11.9% | ||
| Ann C. Donahue | 11.9% | ||
| J. Christopher Donahue | 11.9% | ||
|
Janus Henderson Group PLC
13G/A
Amendment 2
|
9.9% |
8/14/2025
Event 6/30/2025
|
|
| Janus Henderson Group PLC | 9.9% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 9.9% | ||
| Alger Associates, Inc. 13G/A Amendment 6 | 13.3% |
8/14/2025
Event 6/30/2025
|
|
|
Ikarian Capital, LLC
13G/A
Amendment 1
|
4.99% |
8/14/2025
Event 6/30/2025
|
|
| Ikarian Capital, LLC | 4.99% | ||
| Neil Shahrestani | 4.99% | ||
|
Boothbay Fund Management, LLC
13G/A
Amendment 1
|
0.8% |
8/7/2025
Event 6/30/2025
|
|
| Boothbay Fund Management, LLC | 0.8% | ||
| Ari Glass | 0.8% | ||
|
Tybourne Capital Management (HK) Ltd
13G/A
Amendment 2
|
10.0% |
8/4/2025
Event 6/30/2025
|
|
| Tybourne Capital Management (HK) Ltd | 10.0% | ||
| Tybourne Strategic Opportunities GP II Limited | 10.0% | ||
| Tybourne Capital Management Ltd | 10.0% | ||
| Tybourne Kesari Ltd | 10.0% | ||
| Krishnan Viswanathan | 10.0% | ||
|
Federated Hermes, Inc.
13G
|
8.8% |
7/8/2025
Event 6/30/2025
|
|
| Federated Hermes, Inc. | 8.8% | ||
| Voting Shares Irrevocable Trust | 8.8% | ||
| Thomas R. Donahue | 8.8% | ||
| Ann C. Donahue | 8.8% | ||
| J. Christopher Donahue | 8.8% | ||
| Alger Associates, Inc. 13G/A Amendment 5 | 14.2% |
5/15/2025
Event 3/31/2025
|
|
|
Janus Henderson Group PLC
13G/A
Amendment 1
|
9.9% |
5/14/2025
Event 3/31/2025
|
|
| Janus Henderson Group PLC | 9.9% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 9.9% | ||
|
Janus Henderson Group PLC
13G
|
10.0% |
2/14/2025
Event 12/31/2024
|
|
| Janus Henderson Group PLC | 10.0% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 10.0% | ||
| Alger Associates Inc 13G/A Amendment 4 | 17.7% |
2/14/2025
Event 12/31/2024
|
|
|
Perceptive Advisors LLC
13G/A
Amendment 3
|
2.5% |
2/14/2025
Event 12/31/2024
|
|
| Perceptive Advisors LLC | 2.5% | ||
| Joseph Edelman | 2.5% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 2.5% | ||
|
Ikarian Capital, LLC
13G
|
9.5% |
2/14/2025
Event 12/31/2024
|
|
| Ikarian Capital, LLC | 9.5% | ||
| Neil Shahrestani | 9.5% | ||
|
Orbimed Advisors LLC
13G
|
8.0% |
2/14/2025
Event 12/31/2024
|
|
| Orbimed Advisors LLC | 8.0% | ||
| Orbimed Capital LLC | 1.4% | ||
|
Tybourne Capital Management (HK) Ltd
13G/A
Amendment 1
|
10.0% |
2/14/2025
Event 12/31/2024
|
|
| Tybourne Capital Management (HK) Ltd | 10.0% | ||
| Tybourne Strategic Opportunities GP II Limited | 10.0% | ||
| Tybourne Capital Management Ltd | 10.0% | ||
| Tybourne Kesari Ltd | 10.0% | ||
| Krishnan Viswanathan | 10.0% | ||
|
Biotechnology Value Fund L P
13G/A
Amendment 1
|
10.0% |
2/14/2025
Event 12/31/2024
|
|
| Biotechnology Value Fund L P | 5.3% | ||
| BVF I GP LLC | 5.3% | ||
| Biotechnology Value Fund II LP | 4.1% | ||
| BVF II GP LLC | 4.1% | ||
| Biotechnology Value Trading Fund OS LP | 0.5% | ||
| BVF Partners OS Ltd. | 0.5% | ||
| BVF GP Holdings LLC | 9.3% | ||
| BVF Partners L P/IL | 10.0% | ||
| BVF Inc/IL | 10.0% | ||
| Lampert Mark N | 10.0% | ||
|
Boothbay Fund Management, LLC
13G
|
6.0% |
2/13/2025
Event 12/31/2024
|
|
| Boothbay Fund Management, LLC | 6.0% | ||
| Ari Glass | 6.0% | ||
|
Oliveira Steven Michael
13G
|
6.8% |
1/10/2025
Event 11/20/2024
|
|
| Nemean Asset Management, LLC | 6.8% | ||
| Steven M. Oliveira | 6.8% |