Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 282559103 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Deep Track Capital, LP
13G/A
Amendment 3
|
0% |
2/13/2026
Event 12/31/2025
|
|
| Deep Track Capital, LP | 0% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 0% | ||
| David Kroin | 0% | ||
|
Deep Track Capital, LP
13G/A
Amendment 2
|
6.3% |
11/14/2025
Event 9/30/2025
|
|
| Deep Track Capital, LP | 6.3% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 6.3% | ||
| David Kroin | 6.3% | ||
|
Pentwater Capital Management LP
13G
|
0% |
11/14/2025
Event 9/30/2025
|
|
| Pentwater Capital Management LP | 0% | ||
| Matthew Halbower | 0% | ||
|
Suvretta Capital Management, LLC
13G/A
Amendment 5
|
5.6% |
11/13/2025
Event 9/30/2025
|
|
| Suvretta Capital Management, LLC | 5.6% | ||
| Averill Master Fund, Ltd. | 4.8% | ||
| Aaron Cowen | 5.6% | ||
|
RA Capital Management, L.P.
13D/A
Amendment 14
|
0% |
11/3/2025
Event 10/30/2025
|
|
| RA Capital Management, L.P. | 0% | ||
| Peter Kolchinsky | 0% | ||
| Rajeev Shah | 0% | ||
| RA Capital Healthcare Fund, L.P. | 0% | ||
|
Adage Capital Management, L.P.
13D/A
Amendment 1
|
0% |
10/31/2025
Event 10/29/2025
|
|
| Adage Capital Management, L.P. | 0% | ||
| Robert Atchinson | 0% | ||
| Phillip Gross | 0% | ||
| Janus Henderson Group PLC 13G/A Amendment 8 | 3.6% |
10/7/2025
Event 9/30/2025
|
|
|
Adage Capital Management, L.P.
13D
|
6.1% |
10/3/2025
Event 9/26/2025
|
|
| Adage Capital Management, L.P. | 6.1% | ||
| Robert Atchinson | 6.1% | ||
| Phillip Gross | 6.1% | ||
|
Janus Henderson Group PLC
13G/A
Amendment 7
|
14.2% |
8/14/2025
Event 6/30/2025
|
|
| Janus Henderson Group PLC | 14.2% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.1% | ||
| Vanguard Group Inc 13G | 5.6% |
7/29/2025
Event 6/30/2025
|
|
|
Deep Track Capital, LP
13G/A
Amendment 1
|
9.2% |
5/15/2025
Event 3/31/2025
|
|
| Deep Track Capital, LP | 9.2% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 9.2% | ||
| David Kroin | 9.2% | ||
|
RTW Investments, LP
13G/A
Amendment 2
|
1.3% |
5/15/2025
Event 3/31/2025
|
|
| RTW Investments, LP | 1.3% | ||
| Roderick Wong, M.D. | 1.3% | ||
|
Janus Henderson Group PLC
13G/A
Amendment 6
|
14.0% |
5/14/2025
Event 3/31/2025
|
|
| Janus Henderson Group PLC | 14.0% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.1% | ||
|
Suvretta Capital Management, LLC
13G/A
Amendment 4
|
9.9% |
5/2/2025
Event 3/31/2025
|
|
| Suvretta Capital Management, LLC | 9.9% | ||
| Averill Master Fund, Ltd. | 8.8% | ||
| Aaron Cowen | 9.9% | ||
|
RA Capital Management, L.P.
13D/A
Amendment 13
|
13.7% |
3/3/2025
Event 2/27/2025
|
|
| RA Capital Management, L.P. | 13.7% | ||
| Peter Kolchinsky | 13.7% | ||
| Rajeev Shah | 13.7% | ||
| RA Capital Healthcare Fund, L.P. | 13.4% | ||
|
Biotechnology Value Fund L P
13G/A
Amendment 4
|
3.6% |
2/14/2025
Event 12/31/2024
|
|
| Biotechnology Value Fund L P | 1.9% | ||
| BVF I GP LLC | 1.9% | ||
| Biotechnology Value Fund II LP | 1.5% | ||
| BVF II GP LLC | 1.5% | ||
| Biotechnology Value Trading Fund OS LP | 0.2% | ||
| BVF Partners OS Ltd. | 0.2% | ||
| BVF GP Holdings LLC | 3.4% | ||
| BVF Partners L P/IL | 3.6% | ||
| BVF Inc/IL | 3.6% | ||
| Lampert Mark N | 3.6% | ||
|
Suvretta Capital Management, LLC
13G/A
Amendment 3
|
8.5% |
2/13/2025
Event 12/31/2024
|
|
| Suvretta Capital Management, LLC | 8.5% | ||
| Averill Master Fund, Ltd. | 7.7% | ||
| Aaron Cowen | 8.5% | ||
|
Janus Henderson Group PLC
13G/A
Amendment 5
|
15.3% |
2/7/2025
Event 1/31/2025
|
|
| Janus Henderson Group PLC | 15.3% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.6% | ||
|
RA Capital Management, L.P.
13D/A
Amendment 12
|
15.1% |
2/3/2025
Event 1/30/2025
|
|
| RA Capital Management, L.P. | 15.1% | ||
| Peter Kolchinsky | 15.1% | ||
| Rajeev Shah | 15.1% | ||
| RA Capital Healthcare Fund LP | 14.8% | ||
|
Deep Track Capital, LP
13G
|
5.4% |
12/23/2024
Event 12/19/2024
|
|
| Deep Track Capital, LP | 5.4% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 5.4% | ||
| David Kroin | 5.4% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2025 Q4 | 2 | 90.0 k | $1.11 M |
| 2025 Q3 | 230 | 155 M | $2.27 B |
| 2025 Q2 | 208 | 161 M | $1.59 B |
| 2025 Q1 | 204 | 154 M | $1.14 B |
| 2024 Q4 | 167 | 121 M | $947 M |
| 2024 Q3 | 156 | 105 M | $777 M |
| 2024 Q2 | 157 | 104 M | $830 M |
| 2024 Q1 | 167 | 100 M | $1.16 B |
| 2023 Q4 | 168 | 96.5 M | $1.08 B |
| 2023 Q3 | 189 | 72.4 M | $1.12 B |
| 2023 Q2 | 170 | 78.1 M | $1.48 B |
| 2023 Q1 | 183 | 71.9 M | $1.10 B |
| 2022 Q4 | 119 | 46.4 M | $591 M |
| 2022 Q3 | 93 | 40.0 M | $232 M |
| 2022 Q2 | 74 | 32.5 M | $105 M |
| 2022 Q1 | 72 | 17.1 M | $64.3 M |
| 2021 Q4 | 54 | 17.3 M | $226 M |
| 2021 Q3 | 50 | 17.3 M | $339 M |
| 2021 Q2 | 52 | 16.9 M | $315 M |
| 2021 Q1 | 71 | 16.9 M | $401 M |
| 2020 Q4 | 72 | 16.8 M | $409 M |
| 2020 Q3 | 70 | 16.0 M | $411 M |
| 2020 Q2 | 40 | 10.6 M | $215 M |
| 2020 Q1 | 32 | 10.7 M | $270 M |
| 2019 Q4 | 36 | 10.5 M | $276 M |