Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 252828108 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Sirenia Capital Management LP
13G/A
Amendment 1
|
3.1% |
8/14/2026
Event 6/30/2026
|
|
| Sirenia Capital Management LP | 3.1% | ||
| Alex Silverstein | 3.1% | ||
|
Wellington Management Group LLP
13G
|
5.9% |
8/13/2026
Event 6/30/2026
|
|
| Wellington Management Group LLP | 5.9% | ||
| Wellington Group Holdings LLP | 5.9% | ||
| Wellington Investment Advisors Holdings LLP | 5.9% | ||
| Wellington Management Company LLP | 5.5% | ||
| T. Rowe Price Investment Management, Inc. 13G/A Amendment 1 | 12.1% |
8/7/2026
Event 7/31/2026
|
|
| T. Rowe Price Investment Management, Inc. 13G | 7.1% |
8/7/2026
Event 6/30/2026
|
|
| BlackRock, Inc. 13G/A Amendment 1 | 6.4% |
7/28/2026
Event 6/30/2026
|
|
|
RA Capital Management, L.P.
13G/A
Amendment 5
|
4.8% |
5/15/2026
Event 3/31/2026
|
|
| RA Capital Management, L.P. | 4.8% | ||
| Peter Kolchinsky | 4.8% | ||
| Rajeev Shah | 4.8% | ||
| RA Capital Healthcare Fund, L.P. | 4.8% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 2
|
1.2% |
5/15/2026
Event 3/31/2026
|
|
| Point72 Asset Management, L.P. | 1.2% | ||
| Point72 Capital Advisors, Inc. | 1.2% | ||
| Steven A. Cohen | 1.2% | ||
|
Sirenia Capital Management LP
13G
|
5.3% |
5/15/2026
Event 3/31/2026
|
|
| Sirenia Capital Management LP | 5.3% | ||
| Alex Silverstein | 5.3% | ||
|
Wellington Management Group LLP
13G/A
Amendment 1
|
4.8% |
5/15/2026
Event 3/31/2026
|
|
| Wellington Management Group LLP | 4.8% | ||
| Wellington Group Holdings LLP | 4.8% | ||
| Wellington Investment Advisors Holdings LLP | 4.8% | ||
|
Octagon Capital Advisors LP
13G/A
Amendment 3
|
3.6% |
5/14/2026
Event 3/31/2026
|
|
| Octagon Capital Advisors LP | 3.6% | ||
| Octagon Investments Master Fund LP | 3.0% | ||
| Octagon Biotech Opportunities Fund I LP | 0.6% | ||
| Ting Jia | 3.6% | ||
| BlackRock, Inc. 13G | 5.1% |
4/27/2026
Event 3/31/2026
|
|
|
RA Capital Management, L.P.
13G/A
Amendment 4
|
6.0% |
2/17/2026
Event 12/31/2025
|
|
| RA Capital Management, L.P. | 6.0% | ||
| Peter Kolchinsky | 6.0% | ||
| Rajeev Shah | 6.0% | ||
| RA Capital Healthcare Fund, L.P. | 6.0% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 1
|
6.9% |
2/17/2026
Event 12/31/2025
|
|
| Point72 Asset Management, L.P. | 6.9% | ||
| Point72 Capital Advisors, Inc. | 6.9% | ||
| Steven A. Cohen | 6.9% | ||
|
Fairmount Funds Management LLC
13D/A
Amendment 4
|
4.9% |
11/25/2025
Event 11/21/2025
|
|
| Fairmount Funds Management LLC | 4.9% | ||
| Fairmount Healthcare Fund II L.P. | 4.9% | ||
| Peter Evan Harwin | 4.9% | ||
| Tomas Kiselak | 4.9% | ||
|
Avidity Partners Management LP
13D/A
Amendment 3
|
4.9% |
11/19/2025
Event 11/17/2025
|
|
| Avidity Partners Management LP | 4.9% | ||
| Avidity Partners Management (GP) LLC | 4.9% | ||
| Avidity Capital Partners Fund (GP) LP | 4.9% | ||
| Avidity Capital Partners (GP) LLC | 4.9% | ||
| Avidity Private Master Fund I LP | 4.4% | ||
| Michael Gregory | 4.9% | ||
|
RA Capital Management, L.P.
13G/A
Amendment 3
|
9.5% |
11/14/2025
Event 9/30/2025
|
|
| RA Capital Management, L.P. | 9.5% | ||
| Peter Kolchinsky | 9.5% | ||
| Rajeev Shah | 9.5% | ||
| RA Capital Healthcare Fund, L.P. | 9.5% | ||
|
Octagon Capital Advisors LP
13G/A
Amendment 2
|
6.1% |
11/14/2025
Event 9/30/2025
|
|
| Octagon Capital Advisors LP | 6.1% | ||
| Octagon Investments Master Fund LP | 5.3% | ||
| Octagon Private Opportunities Fund II LP | 0.7% | ||
| Ting Jia | 6.1% | ||
| BCLS Fund III Investments, LP 13G/A Amendment 3 | 3.1% |
11/14/2025
Event 9/30/2025
|
|
|
Deep Track Capital, LP
13G/A
Amendment 1
|
0% |
11/14/2025
Event 9/30/2025
|
|
| Deep Track Capital, LP | 0% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 0% | ||
| David Kroin | 0% | ||
|
Vestal Point Capital, LP
13G/A
Amendment 2
|
3.0% |
11/14/2025
Event 9/30/2025
|
|
| Vestal Point Capital, LP | 3.0% | ||
| Ryan Wilder | 3.0% | ||
|
Wellington Management Group LLP
13G
|
6.5% |
11/12/2025
Event 9/30/2025
|
|
| Wellington Management Group LLP | 6.5% | ||
| Wellington Group Holdings LLP | 6.5% | ||
| Wellington Investment Advisors Holdings LLP | 6.5% | ||
| Wellington Management Company LLP | 6.3% | ||
|
FMR LLC
13G/A
Amendment 2
|
15.0% |
11/5/2025
Event 9/30/2025
|
|
| FMR LLC | 15.0% | ||
| Abigail P. Johnson | 15.0% | ||
|
Fairmount Funds Management LLC
13D/A
Amendment 3
|
9.9% |
9/15/2025
Event 9/11/2025
|
|
| Fairmount Funds Management LLC | 9.9% | ||
| Fairmount Healthcare Fund II L.P. | 9.9% | ||
| Fairmount SPV III, LLC | 0% | ||
| Peter Evan Harwin | 9.9% | ||
| Tomas Kiselak | 9.9% | ||
|
Point72 Asset Management, L.P.
13G
|
5.3% |
9/12/2025
Event 9/11/2025
|
|
| Point72 Asset Management, L.P. | 5.3% | ||
| Point72 Capital Advisors, Inc. | 5.3% | ||
| Steven A. Cohen | 5.3% | ||
|
Venrock Healthcare Capital Partners III, L.P.
13G/A
Amendment 2
|
3.1% |
8/14/2025
Event 6/30/2025
|
|
| Venrock Healthcare Capital Partners III, L.P. | 3.1% | ||
| VHCP Co-Investment Holdings III, LLC | 3.1% | ||
| Venrock Healthcare Capital Partners EG, L.P. | 3.1% | ||
| VHCP Management III, LLC | 3.1% | ||
| VHCP Management EG, LLC | 3.1% | ||
| Nimish Shah | 3.1% | ||
| Bong Y. Koh | 3.1% | ||
| BCLS Fund III Investments, LP 13G/A Amendment 2 | 7.5% |
8/14/2025
Event 6/30/2025
|
|
|
Point72 Asset Management, L.P.
13G/A
Amendment 1
|
4.5% |
8/14/2025
Event 6/30/2025
|
|
| Point72 Asset Management, L.P. | 4.5% | ||
| Point72 Capital Advisors, Inc | 4.5% | ||
| Steven A. Cohen | 4.5% | ||
|
Vestal Point Capital, LP
13G/A
Amendment 1
|
10.0% |
8/14/2025
Event 6/30/2025
|
|
| Vestal Point Capital, LP | 10.0% | ||
| Ryan Wilder | 10.0% | ||
|
RA Capital Management, L.P.
13G/A
Amendment 2
|
8.9% |
5/15/2025
Event 3/31/2025
|
|
| RA Capital Management, L.P. | 8.9% | ||
| Peter Kolchinsky | 8.9% | ||
| Rajeev Shah | 8.9% | ||
| RA Capital Healthcare Fund, L.P. | 8.9% | ||
|
TCG Crossover GP II, LLC
13G/A
Amendment 1
|
4.7% |
5/15/2025
Event 3/31/2025
|
|
| TCG Crossover GP II, LLC | 4.7% | ||
| TCG Crossover Fund II, L.P. | 4.7% | ||
| Chen Yu | 4.7% | ||
|
Vestal Point Capital, LP
13G
|
5.3% |
5/15/2025
Event 3/31/2025
|
|
| Vestal Point Capital, LP | 5.3% | ||
| Ryan Wilder | 5.3% | ||
|
FMR LLC
13G/A
Amendment 1
|
14.0% |
5/12/2025
Event 3/31/2025
|
|
| FMR LLC | 14.0% | ||
| Abigail P. Johnson | 14.0% | ||
| BlackRock, Inc. 13G/A Amendment 1 |
5.0%
Checked 5% or less
|
4/24/2025
Event 3/31/2025
|
|
|
Point72 Asset Management, L.P.
13G
|
5.9% |
4/17/2025
Event 4/10/2025
|
|
| Point72 Asset Management, L.P. | 5.9% | ||
| Point72 Capital Advisors, Inc. | 5.9% | ||
| Steven A. Cohen | 5.9% | ||
|
Deep Track Capital, LP
13G
|
7.3% |
3/24/2025
Event 3/17/2025
|
|
| Deep Track Capital, LP | 7.3% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 7.3% | ||
| David Kroin | 7.3% | ||
|
Avidity Partners Management LP
13D/A
Amendment 2
|
9.9% |
3/19/2025
Event 3/17/2025
|
|
| Avidity Partners Management LP | 9.9% | ||
| Avidity Partners Management (GP) LLC | 9.9% | ||
| Avidity Capital Partners Fund (GP) LP | 9.9% | ||
| Avidity Capital Partners (GP) LLC | 9.9% | ||
| Avidity Master Fund LP | 2.3% | ||
| Avidity Private Master Fund I LP | 8.3% | ||
| Michael Gregory | 9.9% | ||
|
RA Capital Management, L.P.
13G/A
Amendment 1
|
9.4% |
2/14/2025
Event 12/31/2024
|
|
| RA Capital Management, L.P. | 9.4% | ||
| Peter Kolchinsky | 9.4% | ||
| Rajeev Shah | 9.4% | ||
| RA Capital Healthcare Fund, L.P. | 9.4% | ||
| BCLS Fund III Investments, LP 13G/A Amendment 1 | 8.8% |
2/14/2025
Event 12/31/2024
|
|
|
Octagon Capital Advisors LP
13G/A
Amendment 1
|
7.1% |
2/5/2025
Event 12/31/2024
|
|
| Octagon Capital Advisors LP | 7.1% | ||
| Octagon Investments Master Fund LP | 6.1% | ||
| Octagon Private Opportunities Fund II LP | 1.0% | ||
| Ting Jia | 7.1% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 5 | 689 | $60.7 k |
| 2026 Q2 | 282 | 70.1 M | $6.47 B |
| 2026 Q1 | 254 | 64.4 M | $5.37 B |
| 2025 Q4 | 171 | 49.1 M | $2.02 B |
| 2025 Q3 | 149 | 46.9 M | $1.85 B |
| 2025 Q2 | 108 | 39.1 M | $729 M |
| 2025 Q1 | 105 | 37.7 M | $685 M |
| 2024 Q4 | 99 | 35.1 M | $766 M |
| 2024 Q3 | 95 | 31.4 M | $859 M |
| 2024 Q2 | 78 | 29.7 M | $770 M |
| 2024 Q1 | 80 | 26.1 M | $784 M |
| 2023 Q4 | 43 | 10.6 M | $110 M |
| 2023 Q3 | 32 | 10.1 M | $136 M |