Investors who own more than 5% of a class must file a Schedule 13D or 13G. Each filer's latest filing for 252828108 since 12/18/2024, largest first.
| Filer | % of Class | Filed | ||
|---|---|---|---|---|
|
FMR LLC
13G/A
|
15.0% |
11/5/2025
Event 9/30/2025
|
||
| FMR LLC | 15.0% | |||
| Abigail P. Johnson | 15.0% | |||
| T. Rowe Price Investment Management, Inc. 13G/A | 12.1% |
8/7/2026
Event 7/31/2026
|
||
| BlackRock, Inc. 13G/A | 6.4% |
7/28/2026
Event 6/30/2026
|
||
|
Wellington Management Group LLP
13G
|
5.9% |
8/13/2026
Event 6/30/2026
|
||
| Wellington Management Group LLP | 5.9% | |||
| Wellington Group Holdings LLP | 5.9% | |||
| Wellington Investment Advisors Holdings LLP | 5.9% | |||
| Wellington Management Company LLP | 5.5% | |||
| Under 5%, checked the "5 percent or less" box, or amended by a later filing (11) | ||||
|
Fairmount Funds Management LLC
13D/A
|
4.9% |
11/25/2025
Event 11/21/2025
|
||
| Fairmount Funds Management LLC | 4.9% | |||
| Fairmount Healthcare Fund II L.P. | 4.9% | |||
| Peter Evan Harwin | 4.9% | |||
| Tomas Kiselak | 4.9% | |||
|
Avidity Partners Management LP
13D/A
|
4.9% |
11/19/2025
Event 11/17/2025
|
||
| Avidity Partners Management LP | 4.9% | |||
| Avidity Partners Management (GP) LLC | 4.9% | |||
| Avidity Capital Partners Fund (GP) LP | 4.9% | |||
| Avidity Capital Partners (GP) LLC | 4.9% | |||
| Avidity Private Master Fund I LP | 4.4% | |||
| Michael Gregory | 4.9% | |||
|
RA Capital Management, L.P.
13G/A
|
4.8% |
5/15/2026
Event 3/31/2026
|
||
| RA Capital Management, L.P. | 4.8% | |||
| Peter Kolchinsky | 4.8% | |||
| Rajeev Shah | 4.8% | |||
| RA Capital Healthcare Fund, L.P. | 4.8% | |||
|
TCG Crossover GP II, LLC
13G/A
|
4.7% |
5/15/2025
Event 3/31/2025
|
||
| TCG Crossover GP II, LLC | 4.7% | |||
| TCG Crossover Fund II, L.P. | 4.7% | |||
| Chen Yu | 4.7% | |||
|
Octagon Capital Advisors LP
13G/A
|
3.6% |
5/14/2026
Event 3/31/2026
|
||
| Octagon Capital Advisors LP | 3.6% | |||
| Octagon Investments Master Fund LP | 3.0% | |||
| Octagon Biotech Opportunities Fund I LP | 0.6% | |||
| Ting Jia | 3.6% | |||
|
Sirenia Capital Management LP
13G/A
|
3.1% |
8/14/2026
Event 6/30/2026
|
||
| Sirenia Capital Management LP | 3.1% | |||
| Alex Silverstein | 3.1% | |||
| BCLS Fund III Investments, LP 13G/A | 3.1% |
11/14/2025
Event 9/30/2025
|
||
|
Venrock Healthcare Capital Partners III, L.P.
13G/A
|
3.1% |
8/14/2025
Event 6/30/2025
|
||
| Venrock Healthcare Capital Partners III, L.P. | 3.1% | |||
| VHCP Co-Investment Holdings III, LLC | 3.1% | |||
| Venrock Healthcare Capital Partners EG, L.P. | 3.1% | |||
| VHCP Management III, LLC | 3.1% | |||
| VHCP Management EG, LLC | 3.1% | |||
| Nimish Shah | 3.1% | |||
| Bong Y. Koh | 3.1% | |||
|
Vestal Point Capital, LP
13G/A
|
3.0% |
11/14/2025
Event 9/30/2025
|
||
| Vestal Point Capital, LP | 3.0% | |||
| Ryan Wilder | 3.0% | |||
|
Point72 Asset Management, L.P.
13G/A
|
1.2% |
5/15/2026
Event 3/31/2026
|
||
| Point72 Asset Management, L.P. | 1.2% | |||
| Point72 Capital Advisors, Inc. | 1.2% | |||
| Steven A. Cohen | 1.2% | |||
|
Deep Track Capital, LP
13G/A
|
0% |
11/14/2025
Event 9/30/2025
|
||
| Deep Track Capital, LP | 0% | |||
| Deep Track Biotechnology Master Fund, Ltd. | 0% | |||
| David Kroin | 0% | |||
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 5 | 689 | $60.7 k |
| 2026 Q2 | 282 | 70.1 M | $6.47 B |
| 2026 Q1 | 254 | 64.4 M | $5.37 B |
| 2025 Q4 | 171 | 49.1 M | $2.02 B |
| 2025 Q3 | 149 | 46.9 M | $1.85 B |
| 2025 Q2 | 108 | 39.1 M | $729 M |
| 2025 Q1 | 105 | 37.7 M | $685 M |
| 2024 Q4 | 99 | 35.1 M | $766 M |
| 2024 Q3 | 95 | 31.4 M | $859 M |
| 2024 Q2 | 78 | 29.7 M | $770 M |
| 2024 Q1 | 80 | 26.1 M | $784 M |
| 2023 Q4 | 43 | 10.6 M | $110 M |
| 2023 Q3 | 32 | 10.1 M | $136 M |