Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 21833P301 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
RA Capital Management, L.P.
13G
|
9.9% |
9/30/2026
Event 9/23/2026
|
|
| RA Capital Management, L.P. | 9.9% | ||
| Peter Kolchinsky | 9.9% | ||
| Rajeev Shah | 9.9% | ||
| RA Capital Healthcare Fund, L.P. | 9.9% | ||
|
Citadel Advisors LLC
13G/A
Amendment 1
|
1.1% |
8/14/2026
Event 6/30/2026
|
|
| Citadel Advisors LLC | 0% | ||
| Citadel Advisors Holdings LP | 0% | ||
| Citadel GP LLC | 0% | ||
| Citadel Securities LLC | 1.1% | ||
| Citadel Securities Group LP | 1.1% | ||
| Citadel Securities GP LLC | 1.1% | ||
| Kenneth Griffin | 1.1% | ||
| BlackRock, Inc. 13G | 5.9% |
7/27/2026
Event 6/30/2026
|
|
|
Octagon Capital Advisors LP
13G/A
Amendment 2
|
0% |
5/14/2026
Event 3/31/2026
|
|
| Octagon Capital Advisors LP | 0% | ||
| Octagon Investments Master Fund LP | 0% | ||
| Ting Jia | 0% | ||
|
Octagon Capital Advisors LP
13G/A
Amendment 1
|
5.4% |
2/10/2026
Event 12/31/2025
|
|
| Octagon Capital Advisors LP | 5.4% | ||
| Octagon Investments Master Fund LP | 5.4% | ||
| Ting Jia | 5.4% | ||
|
Aberdeen Group plc
13G
|
7.5% |
1/16/2026
Event 12/31/2025
|
|
| Aberdeen Group plc | 7.5% | ||
| abrdn Inc. | 7.5% | ||
|
Cormorant Asset Management, LP
13G/A
Amendment 4
|
13.4% |
12/15/2025
Event 12/11/2025
|
|
| Cormorant Asset Management, LP | 13.4% | ||
| Chen Bihua | 13.4% | ||
|
Cormorant Asset Management, LP
13G/A
Amendment 3
|
12.8% |
11/14/2025
Event 11/3/2025
|
|
| Cormorant Asset Management, LP | 12.8% | ||
| Bihua Chen | 12.8% | ||
|
Citadel Advisors LLC
13G
|
5.3% |
11/12/2025
Event 11/4/2025
|
|
| Citadel Advisors LLC | 4.7% | ||
| Citadel Advisors Holdings LP | 4.7% | ||
| Citadel GP LLC | 4.7% | ||
| Citadel Securities LLC | 0.6% | ||
| Citadel Securities Group LP | 0.6% | ||
| Citadel Securities GP LLC | 0.6% | ||
| Kenneth Griffin | 5.3% | ||
| Vanguard Group Inc 13G/A Amendment 2 | 4.9% |
7/29/2025
Event 6/30/2025
|
|
| BlackRock, Inc. 13G/A Amendment 1 | 2.9% |
7/16/2025
Event 6/30/2025
|
|
|
OrbiMed Advisors LLC
13G/A
Amendment 1
|
5.9% |
2/14/2025
Event 12/31/2024
|
|
| OrbiMed Advisors LLC | 3.7% | ||
| OrbiMed Capital LLC | 5.9% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 6 | 77.3 k | $527 k |
| 2026 Q2 | 119 | 13.8 M | $129 M |
| 2026 Q1 | 116 | 12.9 M | $121 M |
| 2025 Q4 | 103 | 13.3 M | $108 M |
| 2025 Q3 | 89 | 8.80 M | $109 M |
| 2025 Q2 | 84 | 9.07 M | $62.6 M |
| 2025 Q1 | 89 | 10.4 M | $55.4 M |
| 2024 Q4 | 105 | 11.0 M | $129 M |
| 2024 Q3 | 125 | 11.8 M | $243 M |
| 2024 Q2 | 115 | 11.0 M | $498 M |
| 2024 Q1 | 95 | 8.94 M | $351 M |
| 2023 Q4 | 38 | 752 k | $4.54 M |
| 2023 Q3 | 29 | 743 k | $5.00 M |
| 2023 Q2 | 31 | 739 k | $5.80 M |
| 2023 Q1 | 31 | 724 k | $5.26 M |
| 2020 Q1 | 1 | 1.00 k | $5.24 k |
| 2019 Q4 | 1 | 1.00 k | $5.46 k |