Investors who own more than 5% of a class must file a Schedule 13D or 13G. Each filer's latest filing for 21077P108 since 12/18/2024, largest first.
| Filer | % of Class | Filed | ||
|---|---|---|---|---|
|
Avidity Partners Management LP
13G/A
|
8.7% |
5/12/2026
Event 3/31/2026
|
||
| Avidity Partners Management LP | 8.7% | |||
| Avidity Partners Management (GP) LLC | 8.7% | |||
| Avidity Capital Partners Fund (GP) LP | 8.7% | |||
| Avidity Capital Partners (GP) LLC | 8.7% | |||
| Avidity Private Master Fund I LP | 7.7% | |||
| Michael Gregory | 8.7% | |||
|
Deep Track Capital, LP
13G/A
|
8.3% |
5/15/2025
Event 3/31/2025
|
||
| Deep Track Capital, LP | 8.3% | |||
| Deep Track Biotechnology Master Fund, Ltd. | 8.3% | |||
| David Kroin | 8.3% | |||
|
Soleus Capital Master Fund, L.P.
13G/A
|
7.6% |
5/8/2026
Event 3/31/2026
|
||
| Soleus Capital Master Fund, L.P. | 7.6% | |||
| Soleus Capital, LLC | 7.6% | |||
| Soleus Capital Group, LLC | 7.6% | |||
| Soleus Capital Management, L.P. | 7.6% | |||
| Soleus GP, LLC | 7.6% | |||
| Guy Levy | 7.6% | |||
| BlackRock, Inc. 13G | 6.7% |
7/27/2026
Event 6/30/2026
|
||
| Under 5%, checked the "5 percent or less" box, or amended by a later filing (7) | ||||
|
Franklin Resources, Inc.
13G/A
|
4.5% |
5/9/2025
Event 3/31/2025
|
||
| Franklin Resources, Inc. | 4.5% | |||
| Charles B. Johnson | 0% | |||
| Rupert H. Johnson, Jr. | 0% | |||
|
Octagon Capital Advisors LP
13G/A
|
3.3% |
7/31/2026
Event 6/30/2026
|
||
| Octagon Capital Advisors LP | 3.3% | |||
| Octagon Investments Master Fund LP | 3.3% | |||
| Ting Jia | 3.3% | |||
| Blue Owl Capital Holdings LP 13G/A | 3.2% |
8/12/2026
Event 6/30/2026
|
||
|
Great Point Partners, LLC
13G/A
|
2.4% |
5/15/2026
Event 3/31/2026
|
||
| Great Point Partners, LLC | 2.4% | |||
| Dr. Jeffrey R. Jay, M.D. | 2.4% | |||
| Ms. Lillian Nordahl | 2.4% | |||
|
Lehr Martin A.
13G/A
|
2.1% |
2/12/2025
Event 12/31/2024
|
||
| Martin Lehr | 2.1% | |||
| Martin Lehr 2000 Trust | 1.1% | |||
| Ellyn Lehr | 1.1% | |||
| MPM BioImpact LLC 13G/A | 1.4% |
8/14/2026
Event 6/30/2026
|
||
| Opaleye Management Inc. 13G/A | 0% |
2/14/2025
Event 12/31/2024
|
||
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 2 | 6.98 k | $2.10 k |
| 2026 Q2 | 79 | 62.8 M | $34.8 M |
| 2026 Q1 | 63 | 79.3 M | $206 M |
| 2025 Q4 | 44 | 65.3 M | $96.0 M |
| 2025 Q3 | 37 | 69.0 M | $66.8 M |
| 2025 Q2 | 40 | 68.6 M | $45.0 M |
| 2025 Q1 | 43 | 71.4 M | $43.7 M |
| 2024 Q4 | 53 | 72.8 M | $76.4 M |
| 2024 Q3 | 44 | 56.7 M | $111 M |
| 2024 Q2 | 36 | 59.0 M | $118 M |
| 2024 Q1 | 27 | 3.94 M | $5.43 M |
| 2023 Q4 | 26 | 3.56 M | $4.02 M |
| 2023 Q3 | 24 | 2.58 M | $3.89 M |
| 2023 Q2 | 23 | 2.24 M | $3.58 M |
| 2023 Q1 | 23 | 1.29 M | $723 k |
| 2022 Q4 | 26 | 3.92 M | $2.57 M |
| 2022 Q3 | 25 | 4.13 M | $4.59 M |
| 2022 Q2 | 21 | 3.64 M | $6.32 M |
| 2022 Q1 | 17 | 2.90 M | $6.30 M |
| 2021 Q4 | 20 | 3.55 M | $9.44 M |