Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 137404109 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
| BlackRock, Inc. 13G | 6.6% |
7/27/2026
Event 6/30/2026
|
|
|
RTW Investments, LP
13G
|
8.8% |
5/15/2026
Event 3/31/2026
|
|
| RTW Investments, LP | 8.8% | ||
| Roderick Wong | 8.8% | ||
| BlackRock, Inc. 13G/A Amendment 1 | 4.2% |
4/27/2026
Event 3/31/2026
|
|
|
Paul B Manning
13D/A
Amendment 1
|
7.9% |
3/18/2026
Event 12/16/2024
|
|
| Paul B Manning | 7.9% | ||
| The Paul B. Manning Revocable Trust dated May 10, 2000 | 3.8% | ||
| BKB Growth Investments, LLC | 1.8% | ||
| BlackRock, Inc. 13G | 5.2% |
1/21/2026
Event 12/31/2025
|
|
|
Acorn Bioventures, L.P.
13G
|
5.2% |
6/30/2025
Event 6/25/2025
|
|
| Acorn Bioventures, L.P. | 2.2% | ||
| Acorn Bioventures 2, L.P. | 3.0% | ||
| Acorn Capital Advisors GP, LLC | 2.2% | ||
| Acorn Capital Advisors GP2, LLC | 3.0% | ||
| Anders Hove | 5.2% | ||
|
Baker Bros. Advisors LP
13G/A
Amendment 1
|
4.99% |
5/15/2025
Event 3/31/2025
|
|
| Baker Bros. Advisors LP | 4.99% | ||
| Baker Bros. Advisors (GP) LLC | 4.99% | ||
| Julian C. Baker | 4.99% | ||
| Felix J. Baker | 4.99% | ||
|
Northpond Ventures, LP
13G/A
Amendment 1
|
0% |
2/14/2025
Event 12/31/2024
|
|
| Northpond Ventures, LP | 0% | ||
| Northpond Ventures GP, LLC | 0% | ||
| Northpond Ventures II, LP | 0% | ||
| Northpond Ventures II GP, LLC | 0% | ||
| Michael P. Rubin | 0% | ||
|
Baker Bros. Advisors LP
13G
|
6.8% |
2/14/2025
Event 12/31/2024
|
|
| Baker Bros. Advisors LP | 6.8% | ||
| Baker Bros. Advisors (GP) LLC | 6.8% | ||
| Julian C. Baker | 6.8% | ||
| Felix J. Baker | 6.8% | ||
|
CVI Investments, Inc.
13G/A
Amendment 1
|
0% |
2/7/2025
Event 12/31/2024
|
|
| CVI Investments, Inc. | 0% | ||
| Heights Capital Management, Inc. | 0% | ||
|
FMR LLC
13G/A
Amendment 1
|
15.0% |
2/7/2025
Event 1/31/2025
|
|
| FMR LLC | 15.0% | ||
| Abigail P. Johnson | 15.0% | ||
|
FMR LLC
13G
|
9.3% |
2/7/2025
Event 12/31/2024
|
|
| FMR LLC | 9.3% | ||
| Abigail P. Johnson | 9.3% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 10 | 301 k | $3.14 M |
| 2026 Q2 | 145 | 50.4 M | $520 M |
| 2026 Q1 | 119 | 43.4 M | $213 M |
| 2025 Q4 | 91 | 23.6 M | $134 M |
| 2025 Q3 | 87 | 22.7 M | $116 M |
| 2025 Q2 | 85 | 23.1 M | $117 M |
| 2025 Q1 | 89 | 21.2 M | $120 M |
| 2024 Q4 | 83 | 20.0 M | $173 M |
| 2024 Q3 | 59 | 6.70 M | $46.4 M |
| 2024 Q2 | 52 | 6.00 M | $37.2 M |
| 2024 Q1 | 22 | 3.78 M | $5.97 M |
| 2023 Q4 | 24 | 4.03 M | $5.92 M |
| 2023 Q3 | 21 | 5.26 M | $4.86 M |
| 2023 Q2 | 21 | 5.37 M | $6.77 M |
| 2023 Q1 | 22 | 5.48 M | $7.44 M |
| 2022 Q4 | 23 | 5.45 M | $9.75 M |
| 2022 Q3 | 27 | 6.09 M | $19.1 M |
| 2022 Q2 | 24 | 6.35 M | $20.6 M |
| 2022 Q1 | 24 | 6.67 M | $34.0 M |
| 2021 Q4 | 21 | 6.95 M | $54.4 M |
| 2021 Q3 | 13 | 4.88 M | $52.9 M |