Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 10919W405 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Cormorant Asset Management, LP
13G/A
Amendment 4
|
9.2% |
8/14/2026
Event 6/30/2026
|
|
| Cormorant Asset Management, LP | 9.2% | ||
| Bihua Chen | 9.2% | ||
|
Adage Capital Management, L.P.
13G/A
Amendment 1
|
3.4% |
8/12/2026
Event 6/30/2026
|
|
| Adage Capital Management, L.P. | 3.4% | ||
| Robert Atchinson | 3.4% | ||
| Phillip Gross | 3.4% | ||
| Ian McDonald 13D/A Amendment 5 | 13.7% |
7/2/2026
Event 11/4/2024
|
|
| Janus Henderson Group PLC 13G/A Amendment 4 | 13.1% |
5/15/2026
Event 3/31/2026
|
|
| Janus Henderson Group PLC 13G/A Amendment 4 | 13.1% |
5/15/2026
Event 3/31/2026
|
|
|
Vestal Point Capital, LP
13G
|
5.0% |
5/15/2026
Event 3/31/2026
|
|
| Vestal Point Capital, LP | 5.0% | ||
| Ryan Wilder | 5.0% | ||
|
Vivo Opportunity Fund Holdings, L.P.
13G/A
Amendment 1
|
5.2% |
5/12/2026
Event 3/31/2026
|
|
| Vivo Opportunity Fund Holdings, L.P. | 5.2% | ||
| Vivo Opportunity, LLC | 5.2% | ||
| Vivo Opportunity Cayman Fund, L.P. | 0.5% | ||
| Vivo Opportunity Cayman, LLC | 0.5% | ||
|
Cormorant Asset Management, LP
13G/A
Amendment 3
|
9.7% |
4/30/2026
Event 4/28/2026
|
|
| Cormorant Asset Management, LP | 9.7% | ||
| Chen Bihua | 9.7% | ||
|
Commodore Capital LP
13G/A
Amendment 2
|
0.3% |
2/17/2026
Event 12/31/2025
|
|
| Commodore Capital LP | 0.3% | ||
| Commodore Capital Master LP | 0.3% | ||
| Janus Henderson Group PLC 13G/A Amendment 3 | 14.9% |
2/17/2026
Event 12/31/2025
|
|
|
Perceptive Advisors LLC
13G/A
Amendment 2
|
4.6% |
2/17/2026
Event 12/31/2025
|
|
| Perceptive Advisors LLC | 4.6% | ||
| Joseph Edelman | 4.6% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 4.6% | ||
|
Cormorant Asset Management, LP
13G/A
Amendment 2
|
10.9% |
2/6/2026
Event 1/31/2026
|
|
| Cormorant Asset Management, LP | 10.9% | ||
| Bihua Chen | 10.9% | ||
|
Vivo Opportunity Fund Holdings, L.P.
13G
|
6.4% |
11/14/2025
Event 9/30/2025
|
|
| Vivo Opportunity Fund Holdings, L.P. | 6.4% | ||
| Vivo Opportunity, LLC | 6.4% | ||
| Vivo Opportunity Cayman Fund, L.P. | 0.7% | ||
| Vivo Opportunity Cayman, LLC | 0.7% | ||
|
Adage Capital Management, L.P.
13G
|
5.6% |
11/13/2025
Event 9/30/2025
|
|
| Adage Capital Management, L.P. | 5.6% | ||
| Robert Atchinson | 5.6% | ||
| Phillip Gross | 5.6% | ||
| Sio Capital Management, LLC 13G/A Amendment 2 | 2.7% |
11/12/2025
Event 9/30/2025
|
|
|
Janus Henderson Group PLC
13G/A
Amendment 2
|
16.3% |
8/14/2025
Event 6/30/2025
|
|
| Janus Henderson Group PLC | 16.3% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 14.0% | ||
| Sio Capital Management, LLC 13G/A Amendment 1 | 7.3% |
8/13/2025
Event 6/30/2025
|
|
|
RA Capital Management, L.P.
13G/A
Amendment 1
|
2.9% |
5/15/2025
Event 3/31/2025
|
|
| RA Capital Management, L.P. | 2.9% | ||
| Peter Kolchinsky | 2.9% | ||
| Rajeev Shah | 2.9% | ||
| RA Capital Healthcare Fund, L.P. | 2.9% | ||
|
Perceptive Advisors LLC
13G/A
Amendment 1
|
6.3% |
5/15/2025
Event 3/31/2025
|
|
| Perceptive Advisors LLC | 6.3% | ||
| Joseph Edelman | 6.3% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 6.3% | ||
| Sio Capital Management, LLC 13G | 7.2% |
4/8/2025
Event 3/31/2025
|
|
|
Janus Henderson Group PLC
13G/A
Amendment 1
|
16.0% |
4/7/2025
Event 3/31/2025
|
|
| Janus Henderson Group PLC | 16.0% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 14.2% | ||
|
Commodore Capital LP
13G/A
Amendment 1
|
7.2% |
2/14/2025
Event 12/31/2024
|
|
| Commodore Capital LP | 7.2% | ||
| Commodore Capital Master LP | 7.2% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 1
|
3.0% |
2/14/2025
Event 12/31/2024
|
|
| Point72 Asset Management, L.P. | 3.0% | ||
| Point72 Capital Advisors, Inc. | 3.0% | ||
| Steven A. Cohen | 3.0% | ||
| Sio Capital Management, LLC 13G | 6.5% |
2/10/2025
Event 12/31/2024
|
|
|
Janus Henderson Group PLC
13G
|
11.6% |
2/7/2025
Event 1/31/2025
|
|
| Janus Henderson Group PLC | 11.6% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 10.4% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 4 | 95.0 | $4.73 k |
| 2026 Q2 | 101 | 9.32 M | $654 M |
| 2026 Q1 | 95 | 9.19 M | $670 M |
| 2025 Q4 | 75 | 6.59 M | $515 M |
| 2025 Q3 | 66 | 6.05 M | $366 M |
| 2025 Q2 | 49 | 5.24 M | $137 M |
| 2025 Q1 | 35 | 5.22 M | $188 M |
| 2024 Q4 | 32 | 4.90 M | $176 M |
| 2024 Q3 | 7 | 192 k | $230 k |
| 2024 Q2 | 7 | 198 k | $208 k |
| 2024 Q1 | 8 | 213 k | $256 k |
| 2023 Q4 | 9 | 228 k | $330 k |
| 2023 Q3 | 7 | 195 k | $309 k |