Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 08205P209 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Franklin Resources, Inc.
13G/A
Amendment 7
|
10.6% |
1/29/2026
Event 12/31/2025
|
|
| Franklin Resources, Inc. | 10.6% | ||
| Charles B. Johnson | 0% | ||
| Rupert H. Johnson, Jr. | 0% | ||
| Franklin Advisers, Inc. | 10.6% | ||
|
Janus Henderson Group PLC
13G/A
Amendment 10
|
10.0% |
12/8/2025
Event 11/28/2025
|
|
| Janus Henderson Group PLC | 10.0% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 6.1% | ||
|
RA Capital Management, L.P.
13G
|
5.5% |
12/3/2025
Event 11/7/2025
|
|
| RA Capital Management, L.P. | 5.5% | ||
| Peter Kolchinsky | 5.5% | ||
| Rajeev Shah | 5.5% | ||
| RA Capital Healthcare Fund, L.P. | 5.5% | ||
|
Suvretta Capital Management, LLC
13D/A
Amendment 4
|
44.1% |
11/10/2025
Event 11/7/2025
|
|
| Suvretta Capital Management, LLC | 44.1% | ||
| Averill Master Fund, Ltd. | 37.8% | ||
| Averill Madison Master Fund, Ltd. | 6.3% | ||
| Aaron Cowen | 44.1% | ||
|
Franklin Resources, Inc.
13G/A
Amendment 6
|
14.9% |
11/4/2025
Event 9/30/2025
|
|
| Franklin Resources, Inc. | 14.9% | ||
| Charles B. Johnson | 0% | ||
| Rupert H. Johnson, Jr. | 0% | ||
| Franklin Advisers, Inc. | 14.9% | ||
|
Janus Henderson Group PLC
13G/A
Amendment 9
|
11.3% |
8/14/2025
Event 6/30/2025
|
|
| Janus Henderson Group PLC | 11.3% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 8.6% | ||
|
Janus Henderson Group PLC
13G/A
Amendment 8
|
11.3% |
8/14/2025
Event 6/30/2025
|
|
| Janus Henderson Group PLC | 11.3% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 8.6% | ||
|
Nantahala Capital Management, LLC
13G/A
Amendment 1
|
4.4% |
5/15/2025
Event 3/31/2025
|
|
| Nantahala Capital Management, LLC | 4.4% | ||
| Wilmot B. Harkey | 4.4% | ||
| Daniel Mack | 4.4% | ||
|
Janus Henderson Group PLC
13G/A
Amendment 7
|
11.4% |
5/14/2025
Event 3/31/2025
|
|
| Janus Henderson Group PLC | 11.4% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 8.6% | ||
|
Franklin Resources, Inc.
13G/A
Amendment 5
|
16.3% |
5/9/2025
Event 3/31/2025
|
|
| Franklin Resources, Inc. | 16.3% | ||
| Charles B. Johnson | 0% | ||
| Rupert H. Johnson, Jr. | 0% | ||
| Franklin Advisers, Inc. | 16.3% | ||
|
Suvretta Capital Management, LLC
13D/A
Amendment 3
|
49.9% |
3/28/2025
Event 3/26/2025
|
|
| Suvretta Capital Management, LLC | 49.9% | ||
| Averill Master Fund, Ltd. | 44.5% | ||
| Averill Madison Master Fund, Ltd. | 5.4% | ||
| Aaron Cowen | 49.9% | ||
|
Janus Henderson Group PLC
13G/A
Amendment 6
|
11.3% |
2/14/2025
Event 12/31/2024
|
|
| Janus Henderson Group PLC | 11.3% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 8.6% | ||
| HBM Healthcare Investments (Cayman) Ltd. 13G/A Amendment 2 | 4.5% |
2/13/2025
Event 12/31/2024
|
|
|
Franklin Resources, Inc.
13G/A
Amendment 4
|
18.1% |
1/27/2025
Event 12/31/2024
|
|
| Franklin Resources, Inc. | 18.1% | ||
| Charles B. Johnson | 0% | ||
| Rupert H. Johnson, Jr. | 0% | ||
| Franklin Advisers, Inc. | 18.1% | ||
|
Nantahala Capital Management, LLC
13G
|
9.7% |
11/14/2024
Event 9/30/2024
|
|
| Nantahala Capital Management, LLC | 9.7% | ||
| Wilmot B. Harkey | 9.7% | ||
| Daniel Mack | 9.7% | ||
|
Franklin Resources, Inc.
13G/A
Amendment 3
|
15.1% |
11/7/2024
Event 9/30/2024
|
|
| Franklin Resources, Inc. | 15.1% | ||
| Charles B. Johnson | 0% | ||
| Rupert H. Johnson, Jr. | 0% | ||
| Franklin Advisers, Inc. | 15.1% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 2 | 8.29 k | $82.9 k |
| 2026 Q2 | 90 | 34.7 M | $464 M |
| 2026 Q1 | 89 | 32.5 M | $346 M |
| 2025 Q4 | 73 | 31.7 M | $427 M |
| 2025 Q3 | 58 | 23.2 M | $325 M |
| 2025 Q2 | 60 | 22.7 M | $265 M |
| 2025 Q1 | 39 | 21.9 M | $290 M |
| 2024 Q4 | 31 | 19.0 M | $240 M |
| 2024 Q3 | 26 | 13.7 M | $127 M |
| 2024 Q2 | 20 | 5.74 M | $40.0 M |
| 2024 Q1 | 16 | 1.29 M | $6.70 M |
| 2023 Q4 | 15 | 1.20 M | $3.90 M |
| 2023 Q3 | 12 | 1.27 M | $3.84 M |