Investors who own more than 5% of a class must file a Schedule 13D or 13G. Each filer's latest filing for 019770106 since 12/18/2024, largest first.
| Filer | % of Class | Filed | ||
|---|---|---|---|---|
| Pfizer Inc. 13D/A | 9.0% |
2/13/2026
Event 11/6/2025
|
||
|
Frazier Life Sciences Public Fund, L.P.
13G/A
|
5.6% |
8/14/2026
Event 6/30/2026
|
||
| Frazier Life Sciences Public Fund, L.P. | 5.6% | |||
| FHMLSP, L.P. | 5.6% | |||
| FHMLSP, L.L.C. | 5.6% | |||
| Frazier Life Sciences X, L.P. | 0.1% | |||
| FHMLS X, L.P. | 0.1% | |||
| FHMLS X, L.L.C. | 0.1% | |||
| Frazier Life Sciences XI, L.P. | 0.2% | |||
| FHMLS XI, L.P. | 0.2% | |||
| FHMLS XI, L.L.C. | 0.2% | |||
| Frazier Life Sciences XII, L.P. | 0.6% | |||
| FHMLS XII, L.P. | 0.6% | |||
| FHMLS XII, L.L.C. | 0.6% | |||
| James N. Topper | 0.1% | |||
| Patrick J. Heron | 0.1% | |||
| State Street Corp 13G | 5.5% |
8/7/2026
Event 6/30/2026
|
||
| BlackRock, Inc. 13G/A | 5.3% |
4/17/2025
Event 3/31/2025
|
||
| Under 5%, checked the "5 percent or less" box, or amended by a later filing (7) | ||||
|
Chang David D
13G/A
|
4.9% |
5/13/2026
Event 3/31/2026
|
||
| David D. Chang, M.D., Ph.D. | 4.9% | |||
| Chang 2006 Family Trust | 0.5% | |||
| JEC 2019 Trust | 0.3% | |||
| RTC 2019 Trust | 0.3% | |||
|
FMR LLC
13G/A
|
4.9% |
3/7/2025
Event 2/28/2025
|
||
| FMR LLC | 4.9% | |||
| Abigail P. Johnson | 4.9% | |||
|
Belldegrun Arie
13G/A
|
3.9% |
8/7/2026
Event 6/30/2026
|
||
| Arie Belldegrun, M.D. | 3.9% | |||
| Bellco Legacy LLC | 0.2% | |||
| Bellco Legacy IV LLC | 1.3% | |||
| Vida Ventures LLC | 0.5% | |||
| Vida Ventures III, L.P. | 0.5% | |||
| Vida Ventures III-A, L.P. | 0% | |||
|
Citadel Advisors LLC
13G/A
|
2.8% |
5/15/2026
Event 3/31/2026
|
||
| Citadel Advisors LLC | 2.4% | |||
| Citadel Advisors Holdings LP | 2.4% | |||
| Citadel GP LLC | 2.4% | |||
| Citadel Securities LLC | 0.3% | |||
| Citadel Securities Group LP | 0.4% | |||
| Citadel Securities GP LLC | 0.4% | |||
| Kenneth Griffin | 2.8% | |||
| Capital World Investors 13G/A | 0% |
11/13/2025
Event 9/30/2025
|
||
|
Lynx1 Capital Management LP
13G/A
|
0% |
5/15/2026
Event 12/31/2025
|
||
| Lynx1 Capital Management LP | 0% | |||
| Weston Nichols | 0% | |||
|
TPG GP A, LLC
13D/A
|
0% |
9/30/2026
Event 9/28/2026
|
||
| TPG GP A, LLC | 0% | |||
| James G. Coulter | 0% | |||
| Jon Winkelried | 0% | |||
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 3 | 19.0 k | $30.4 k |
| 2026 Q2 | 218 | 313 M | $656 M |
| 2026 Q1 | 217 | 184 M | $445 M |
| 2025 Q4 | 182 | 163 M | $223 M |
| 2025 Q3 | 178 | 163 M | $202 M |
| 2025 Q2 | 165 | 185 M | $209 M |
| 2025 Q1 | 178 | 197 M | $302 M |
| 2024 Q4 | 180 | 189 M | $402 M |
| 2024 Q3 | 163 | 168 M | $472 M |
| 2024 Q2 | 183 | 172 M | $400 M |
| 2024 Q1 | 170 | 141 M | $629 M |
| 2023 Q4 | 177 | 134 M | $431 M |
| 2023 Q3 | 159 | 130 M | $413 M |
| 2023 Q2 | 176 | 133 M | $663 M |
| 2023 Q1 | 184 | 118 M | $582 M |
| 2022 Q4 | 178 | 121 M | $759 M |
| 2022 Q3 | 203 | 106 M | $1.15 B |
| 2022 Q2 | 166 | 101 M | $1.15 B |
| 2022 Q1 | 193 | 92.1 M | $840 M |
| 2021 Q4 | 192 | 86.2 M | $1.29 B |
| 2021 Q3 | 175 | 88.0 M | $2.26 B |
| 2021 Q2 | 196 | 86.3 M | $2.25 B |
| 2021 Q1 | 180 | 89.5 M | $3.16 B |
| 2020 Q4 | 174 | 89.7 M | $2.26 B |
| 2020 Q3 | 176 | 85.3 M | $3.21 B |
| 2020 Q2 | 191 | 88.7 M | $3.80 B |
| 2020 Q1 | 123 | 73.8 M | $1.44 B |
| 2019 Q4 | 125 | 72.3 M | $1.88 B |
| 2019 Q3 | 106 | 90.1 M | $2.46 B |
| 2019 Q2 | 108 | 69.4 M | $1.86 B |
| 2019 Q1 | 96 | 65.7 M | $1.89 B |
| 2018 Q4 | 84 | 63.0 M | $1.69 B |
| 2016 Q1 | 1 | 4.03 k | $115 k |