| Quarter | Holdings | Value ($000) | Top Holdings | Form Type | Date Filed | Filing ID |
|---|---|---|---|---|---|---|
| Q4 2023 | 70 | 2,795,946 | IMGN, KRYS, FOLD, SRRK | 13F-HR | 2/14/2024 | 000110465924023671 |
| Q3 2023 | 68 | 2,101,757 | IMGN, KRYS, FOLD, AKRO | 13F-HR | 11/14/2023 | 000110465923118113 |
| Q2 2023 | 72 | 2,605,471 | IMGN, KRYS, FOLD, REPL | 13F-HR | 8/14/2023 | 000110465923091352 |
| Q1 2023 | 76 | 2,304,694 | FOLD, KRYS, ISEE, DCPH | 13F-HR | 5/15/2023 | 000110465923060787 |
| Q4 2022 | 69 | 2,444,691 | FOLD, KRYS, AKRO, REPL | 13F-HR | 2/14/2023 | 000110465923021651 |
| Q3 2022 | 70 | 2,578,101 | FATE, FOLD, KRYS, ARGX | 13F-HR | 11/14/2022 | 000110465922118504 |
| Q2 2022 | 71 | 2,618,868 | FATE, FOLD, SGEN, ARGX | 13F-HR | 8/15/2022 | 000110465922091334 |
| Q1 2022 | 70 | 3,203,503 | FATE, FOLD, ARGX, LIVN | 13F-HR | 5/16/2022 | 000110465922061323 |
| Q4 2021 | 71 | 4,398,640 | FATE, FOLD, SNCE, ARGX | 13F-HR | 2/14/2022 | 000110465922023119 |
| Q3 2021 | 75 | 5,733,591 | FATE, ALLK, IGMS, ARGX | 13F-HR | 11/15/2021 | 000110465921139186 |
| Q2 2021 | 86 | 6,757,873 | FATE, IGMS, BEAM, ARGX | 13F-HR | 8/16/2021 | 000110465921106432 |
| Q1 2021 | 86 | 7,099,728 | FATE, ALLK, IGMS, ARGX | 13F-HR | 5/17/2021 | 000110465921068036 |
| Q4 2020 | 87 | 8,258,586 | FATE, FOLD, ALLK, BEAM | 13F-HR | 2/16/2021 | 000110465921023918 |
| Q3 2020 | 81 | 5,447,026 | FATE, FOLD, IMMU, ARGX | 13F-HR | 11/16/2020 | 000110465920125805 |
| Q2 2020 | 80 | 5,416,834 | FATE, FOLD, DCPH, ADCT | 13F-HR | 8/14/2020 | 000110465920095551 |
| Q1 2020 | 69 | 3,566,983 | FATE, FOLD, DCPH, BIIB | 13F-HR | 5/15/2020 | 000110465920062580 |
| Q4 2019 | 64 | 4,180,807 | DCPH, ALLK, FOLD, FATE | 13F-HR | 2/14/2020 | 000110465920021735 |
| Q3 2019 | 74 | 2,988,202 | ALLK, FOLD, FATE, DCPH | 13F-HR | 11/14/2019 | 000110465919064199 |
| Q2 2019 | 81 | 3,533,912 | ARRY, FOLD, FATE, ARGX | 13F-HR | 8/14/2019 | 000114420419040055 |
| Q1 2019 | 82 | 3,417,745 | ARRY, FOLD, FATE, ATRA | RESTATEMENT | 5/20/2019 | 000114420419027165 |
| Q4 2018 | 78 | 2,486,494 | ARRY, ATRA, FATE, XNCR | RESTATEMENT | 5/16/2019 | 000142573819000004 |
| Q3 2018 | 83 | 3,250,425 | ARRY, ATRA, FATE, RGNX | RESTATEMENT | 5/16/2019 | 000142573819000003 |
| Q2 2018 | 81 | 2,943,811 | ARRY, FOLD, ATRA, IMGN | 13F-HR | 8/14/2018 | 000142573818000026 |
| Q1 2018 | 64 | 2,589,659 | ARRY, ATRA, FOLD, IMGN | 13F-HR | 5/15/2018 | 000142573818000025 |
| Q4 2017 | 1 | 6,604 | LIFE | NEW HOLDINGS | 3/8/2018 | 000142573818000018 |
| Q4 2017 | 69 | 2,293,585 | ARRY, FOLD, PBYI, CLVSQ | 13F-HR | 2/14/2018 | 000142573818000017 |
| Q3 2017 | 65 | 2,027,191 | ARRY, FOLD, PBYI, SGEN | 13F-HR | 11/14/2017 | 000142573817000017 |
| Q2 2017 | 64 | 1,642,718 | ARRY, FOLD, PEN, PBYI | 13F-HR | 8/15/2017 | 000142573817000014 |
| Q1 2017 | 60 | 1,540,736 | ARRY, PEN, FOLD, PBYI | 13F-HR | 5/15/2017 | 000142573817000012 |
| Q4 2016 | 50 | 1,160,076 | ARRY, SGEN, CLVSQ, PEN | 13F-HR | 2/14/2017 | 000142573817000010 |
| Q3 2016 | 51 | 1,257,292 | ARRY, SGEN, FOLD, CLVSQ | 13F-HR | 11/15/2016 | 000142573816000040 |
| Q2 2016 | 54 | 1,046,928 | ARRY, FOLD, MDVN, SGEN | 13F-HR | 8/16/2016 | 000142573816000039 |
| Q1 2016 | 47 | 977,072 | FOLD, MDVN, CLVSQ, PEN | 13F-HR | 5/16/2016 | 000142573816000037 |
| Q4 2015 | 57 | 1,336,352 | FOLD, MDVN, PEN, ARRY | 13F-HR | 2/16/2016 | 000142573816000035 |
| Q3 2015 | 58 | 1,319,989 | FOLD, CLVSQ, ARRY, MDVN | RESTATEMENT | 11/17/2015 | 000142573815000021 |
| Q2 2015 | 55 | 1,220,168 | ARRY, FOLD, BHC, CLVSQ | 13F-HR | 8/14/2015 | 000142573815000017 |
| Q1 2015 | 54 | 1,113,749 | ARRY, CLVSQ, FOLD, BHC | 13F-HR | 5/18/2015 | 000142573815000014 |
| Q4 2014 | 54 | 918,447 | FOLD, ARRY, BHC, CMRX | 13F-HR | 2/18/2015 | 000159754915000003 |
| Q3 2014 | 54 | 865,753 | ISHARES TR puts, BHC, ACTAVIS PLC, CLVSQ | 13F-HR | 11/14/2014 | 000132130014000007 |
| Q2 2014 | 48 | 824,504 | ACTAVIS PLC, MDT, ARRY, UHS | 13F-HR | 8/15/2014 | 000142573814000003 |
| Q1 2014 | 55 | 837,581 | ACTAVIS PLC, HCA, A, BHC | RESTATEMENT | 8/19/2014 | 000142573814000004 |
| Q4 2013 | 56 | 810,358 | GILD, CLVSQ, ZBH, CELG | 13F-HR | 2/14/2014 | 000142573814000001 |