Investors who own more than 5% of a class must file a Schedule 13D or 13G. Each filer's latest filing for 046513206 since 12/18/2024, largest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
EcoR1 Capital, LLC
13G/A
|
17.4% |
5/7/2026
Event 5/7/2026
|
|
| EcoR1 Capital, LLC | 17.4% | ||
| Oleg Nodelman | 17.4% | ||
| EcoR1 Capital Fund Qualified, L.P. | 16.2% | ||
|
Redmile Group, LLC
13D/A
|
9.9% |
7/24/2026
Event 7/22/2026
|
|
| Redmile Group, LLC | 9.9% | ||
| Green Jeremy | 9.9% | ||
| Redmile Biopharma Investments II, L.P. | 6.6% | ||
| Redmile Strategic Long Only Trading Sub, Ltd. | 4.2% | ||
|
Panacea Innovation Ltd
13G
|
9.5% |
2/6/2025
Event 1/30/2025
|
|
| Panacea Venture Healthcare Fund II, L.P. | 9.5% | ||
| Panacea Venture Healthcare Fund II GP Company, Ltd. | 9.5% | ||
| Panacea Innovation Limited | 9.5% | ||
| James Huang | 9.5% | ||
|
Adage Capital Management, L.P.
13G
|
8.6% |
5/13/2026
Event 3/31/2026
|
|
| Adage Capital Management, L.P. | 8.6% | ||
| Robert Atchinson | 8.6% | ||
| Phillip Gross | 8.6% | ||
|
Point72 Asset Management, L.P.
13G/A
|
7.6% |
8/14/2026
Event 6/30/2026
|
|
| Point72 Asset Management, L.P. | 7.6% | ||
| Point72 Capital Advisors, Inc. | 7.6% | ||
| Steven A. Cohen | 7.6% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q2 | 36 | 4.47 M | $51.3 M |
| 2026 Q1 | 33 | 2.56 M | $12.1 M |
| 2025 Q4 | 42 | 2.05 M | $37.1 M |
| 2025 Q3 | 38 | 1.88 M | $27.0 M |
| 2025 Q2 | 34 | 1.80 M | $13.9 M |
| 2025 Q1 | 38 | 2.09 M | $12.4 M |
| 2024 Q4 | 43 | 2.39 M | $31.8 M |
| 2024 Q3 | 36 | 2.42 M | $19.6 M |
| 2024 Q2 | 49 | 2.67 M | $22.7 M |