Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 86366E106 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
FMR LLC
13G/A
Amendment 6
|
13.2% |
8/6/2026
Event 6/30/2026
|
|
| FMR LLC | 13.2% | ||
| Abigail P. Johnson | 13.2% | ||
|
Biotechnology Value Fund L P
13G/A
Amendment 1
|
4.9% |
2/17/2026
Event 12/31/2025
|
|
| Biotechnology Value Fund L P | 2.6% | ||
| BVF I GP LLC | 2.6% | ||
| Biotechnology Value Fund II LP | 1.9% | ||
| BVF II GP LLC | 1.9% | ||
| Biotechnology Value Trading Fund OS LP | 0.3% | ||
| BVF Partners OS Ltd. | 0.3% | ||
| BVF GP Holdings LLC | 4.5% | ||
| BVF Partners L P/IL | 4.9% | ||
| BVF Inc/IL | 4.9% | ||
| Lampert Mark N | 4.9% | ||
|
Deep Track Capital, LP
13G/A
Amendment 4
|
6.0% |
2/13/2026
Event 12/31/2025
|
|
| Deep Track Capital, LP | 6.0% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 6.0% | ||
| David Kroin | 6.0% | ||
|
Wellington Management Group LLP
13G/A
Amendment 6
|
10.1% |
2/10/2026
Event 12/31/2025
|
|
| Wellington Management Group LLP | 10.1% | ||
| Wellington Group Holdings LLP | 10.1% | ||
| Wellington Investment Advisors Holdings LLP | 10.1% | ||
| Wellington Management Company LLP | 9.6% | ||
|
FMR LLC
13G/A
Amendment 5
|
15.0% |
2/5/2026
Event 12/31/2025
|
|
| FMR LLC | 15.0% | ||
| Abigail P. Johnson | 15.0% | ||
| Janus Henderson Group PLC 13G/A Amendment 4 | 7.7% |
11/14/2025
Event 9/30/2025
|
|
|
Deep Track Capital, LP
13G/A
Amendment 3
|
7.3% |
11/14/2025
Event 9/30/2025
|
|
| Deep Track Capital, LP | 7.3% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 7.3% | ||
| David Kroin | 7.3% | ||
|
Avoro Capital Advisors LLC
13G
|
9.4% |
11/14/2025
Event 9/30/2025
|
|
| Avoro Capital Advisors LLC | 9.4% | ||
| Aghazadeh Behzad | 9.4% | ||
|
Wellington Management Group LLP
13G/A
Amendment 5
|
11.9% |
11/7/2025
Event 10/31/2025
|
|
| Wellington Management Group LLP | 11.9% | ||
| Wellington Group Holdings LLP | 11.9% | ||
| Wellington Investment Advisors Holdings LLP | 11.9% | ||
| Wellington Management Company LLP | 11.5% | ||
|
Wellington Management Group LLP
13G/A
Amendment 4
|
9.9% |
11/7/2025
Event 9/30/2025
|
|
| Wellington Management Group LLP | 9.9% | ||
| Wellington Group Holdings LLP | 9.9% | ||
| Wellington Investment Advisors Holdings LLP | 9.9% | ||
| Wellington Management Company LLP | 9.5% | ||
|
Biotechnology Value Fund L P
13G
|
5.6% |
8/18/2025
Event 8/11/2025
|
|
| Biotechnology Value Fund L P | 2.9% | ||
| BVF I GP LLC | 2.9% | ||
| Biotechnology Value Fund II LP | 2.3% | ||
| BVF II GP LLC | 2.3% | ||
| Biotechnology Value Trading Fund OS LP | 0.3% | ||
| BVF Partners OS Ltd. | 0.3% | ||
| BVF GP Holdings LLC | 5.1% | ||
| BVF Partners L P/IL | 5.6% | ||
| BVF Inc/IL | 5.6% | ||
| Lampert Mark N | 5.6% | ||
| Janus Henderson Group PLC 13G/A Amendment 3 | 8.0% |
8/14/2025
Event 6/30/2025
|
|
|
Deep Track Capital, LP
13G/A
Amendment 2
|
8.9% |
8/14/2025
Event 6/30/2025
|
|
| Deep Track Capital, LP | 8.9% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 8.9% | ||
| David Kroin | 8.9% | ||
|
Wellington Management Group LLP
13G/A
Amendment 3
|
12.0% |
8/12/2025
Event 6/30/2025
|
|
| Wellington Management Group LLP | 12.0% | ||
| Wellington Group Holdings LLP | 12.0% | ||
| Wellington Investment Advisors Holdings LLP | 12.0% | ||
| Wellington Management Company LLP | 11.6% | ||
|
FMR LLC
13G/A
Amendment 4
|
11.6% |
8/6/2025
Event 6/30/2025
|
|
| FMR LLC | 11.6% | ||
| Abigail P. Johnson | 11.6% | ||
|
Deep Track Capital, LP
13G/A
Amendment 1
|
7.2% |
5/15/2025
Event 3/31/2025
|
|
| Deep Track Capital, LP | 7.2% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 7.2% | ||
| David Kroin | 7.2% | ||
| Janus Henderson Group PLC 13G/A Amendment 2 | 7.6% |
5/14/2025
Event 3/31/2025
|
|
| Capital Research Global Investors 13G/A Amendment 1 | 3.8% |
5/13/2025
Event 3/31/2025
|
|
| Janus Henderson Group PLC 13G/A Amendment 1 | 7.3% |
2/14/2025
Event 12/31/2024
|
|
|
Deep Track Capital, LP
13G
|
5.2% |
1/13/2025
Event 1/6/2025
|
|
| Deep Track Capital, LP | 5.2% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 5.2% | ||
| David Kroin | 5.2% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 3 | 32.3 k | $1.01 M |
| 2026 Q2 | 201 | 67.6 M | $3.62 B |
| 2026 Q1 | 212 | 67.0 M | $3.23 B |
| 2025 Q4 | 213 | 65.8 M | $4.58 B |
| 2025 Q3 | 176 | 56.7 M | $1.58 B |
| 2025 Q2 | 191 | 54.7 M | $1.13 B |
| 2025 Q1 | 168 | 56.0 M | $981 M |
| 2024 Q4 | 189 | 60.7 M | $1.65 B |
| 2024 Q3 | 181 | 61.6 M | $2.70 B |
| 2024 Q2 | 201 | 60.5 M | $2.38 B |
| 2024 Q1 | 150 | 44.3 M | $1.89 B |
| 2023 Q4 | 143 | 43.3 M | $1.77 B |
| 2023 Q3 | 86 | 32.8 M | $1.64 B |
| 2023 Q2 | 49 | 17.6 M | $699 M |
| 2023 Q1 | 40 | 14.8 M | $346 M |