Investors who own more than 5% of a class must file a Schedule 13D or 13G. Each filer's latest filing for 80706P103 since 12/18/2024, largest first.
| Filer | % of Class | Filed | ||
|---|---|---|---|---|
|
FMR LLC
13G/A
|
15.0% |
2/12/2025
Event 12/31/2024
|
||
| FMR LLC | 15.0% | |||
| Abigail P. Johnson | 15.0% | |||
|
Invus Global Management, LLC
13G/A
|
8.0% |
8/13/2026
Event 6/30/2026
|
||
| Invus Public Equities, L.P. | 8.0% | |||
| Invus Public Equities Advisors, LLC | 8.0% | |||
| Invus Global Management, LLC | 8.0% | |||
| Siren, L.L.C. | 8.0% | |||
| Raymond Debbane | 8.0% | |||
|
Samsara BioCapital, L.P.
13D/A
|
7.2% |
10/7/2025
Event 10/3/2025
|
||
| Samsara BioCapital, L.P. | 6.6% | |||
| Samsara BioCapital GP, LLC | 6.6% | |||
| Samsara Opportunity Fund, L.P. | 0.5% | |||
| Samsara Opportunity Fund GP, LLC | 0.5% | |||
| Srinivas Akkaraju | 7.2% | |||
|
Wellington Management Group LLP
13G
|
5.6% |
2/10/2026
Event 12/31/2025
|
||
| Wellington Management Group LLP | 5.6% | |||
| Wellington Group Holdings LLP | 5.6% | |||
| Wellington Investment Advisors Holdings LLP | 5.6% | |||
| Wellington Management Company LLP | 5.3% | |||
| Price T Rowe Associates Inc /MD/ 13G/A | 5.4% |
5/15/2026
Event 3/31/2026
|
||
| Under 5%, checked the "5 percent or less" box, or amended by a later filing (2) | ||||
|
Redmile Group, LLC
13G/A
|
3.6% |
8/14/2026
Event 6/30/2026
|
||
| Redmile Group, LLC | 3.6% | |||
| Jeremy C. Green | 3.6% | |||
| RedCo II Master Fund, L.P. | 0% | |||
| Vanguard Group Inc 13G/A | 0% |
3/27/2026
Event 3/13/2026
|
||
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 3 | 2.65 k | $128 k |
| 2026 Q2 | 319 | 143 M | $7.71 B |
| 2026 Q1 | 297 | 134 M | $6.58 B |
| 2025 Q4 | 296 | 124 M | $5.44 B |
| 2025 Q3 | 276 | 117 M | $4.35 B |
| 2025 Q2 | 255 | 110 M | $3.91 B |
| 2025 Q1 | 247 | 107 M | $3.43 B |
| 2024 Q4 | 260 | 104 M | $4.51 B |
| 2024 Q3 | 178 | 88.8 M | $711 M |
| 2024 Q2 | 178 | 86.1 M | $718 M |
| 2024 Q1 | 171 | 85.4 M | $1.52 B |
| 2023 Q4 | 142 | 83.6 M | $1.57 B |
| 2023 Q3 | 93 | 53.9 M | $383 M |
| 2023 Q2 | 87 | 51.2 M | $386 M |
| 2023 Q1 | 91 | 46.8 M | $374 M |
| 2022 Q4 | 86 | 45.7 M | $413 M |
| 2022 Q3 | 86 | 45.2 M | $313 M |
| 2022 Q2 | 89 | 45.3 M | $249 M |
| 2022 Q1 | 98 | 31.3 M | $403 M |
| 2021 Q4 | 94 | 29.8 M | $740 M |
| 2021 Q3 | 103 | 28.9 M | $953 M |
| 2021 Q2 | 106 | 28.6 M | $825 M |
| 2021 Q1 | 128 | 27.9 M | $1.41 B |
| 2020 Q4 | 114 | 26.9 M | $1.30 B |
| 2020 Q3 | 71 | 21.2 M | $376 M |
| 2020 Q2 | 71 | 20.2 M | $368 M |
| 2020 Q1 | 66 | 19.5 M | $237 M |
| 2019 Q4 | 60 | 19.1 M | $251 M |
| 2019 Q3 | 58 | 18.1 M | $162 M |
| 2019 Q2 | 67 | 18.1 M | $287 M |
| 2019 Q1 | 46 | 14.1 M | $266 M |
| 2018 Q4 | 43 | 13.5 M | $309 M |
| 2018 Q3 | 42 | 13.4 M | $341 M |
| 2018 Q2 | 29 | 12.5 M | $191 M |