Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 74006W207 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Orbis Investment Management Ltd
13G/A
Amendment 2
|
5.5% |
8/14/2026
Event 6/30/2026
|
|
| Orbis Investment Management Ltd | 5.5% | ||
| Allan Gray Australia Pty Ltd | 0% | ||
|
Baker Bros. Advisors LP
13G
|
6.3% |
5/15/2026
Event 3/31/2026
|
|
| Baker Bros. Advisors LP | 6.3% | ||
| Baker Bros. Advisors (GP) LLC | 6.3% | ||
| Julian C. Baker | 6.3% | ||
| Felix J. Baker | 6.3% | ||
|
Orbis Investment Management Ltd
13G/A
Amendment 1
|
8.9% |
5/15/2026
Event 3/31/2026
|
|
| Orbis Investment Management Ltd | 8.9% | ||
| Allan Gray Australia Pty Ltd | 0% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 8
|
0.2% |
5/15/2026
Event 3/31/2026
|
|
| Point72 Asset Management, L.P. | 0% | ||
| Point72 Capital Advisors, Inc. | 0% | ||
| Point72 Biotech Private Investments, LLC | 0.2% | ||
| Differentiated Ventures Investments, LLC | 0.2% | ||
| 72 Investment Holdings, LLC | 0.2% | ||
| Steven A. Cohen | 0.2% | ||
|
FMR LLC
13G/A
Amendment 1
|
7.7% |
5/6/2026
Event 3/31/2026
|
|
| FMR LLC | 7.7% | ||
| Abigail P. Johnson | 7.7% | ||
| Vanguard Capital Management LLC 13G | 5.1% |
4/30/2026
Event 3/31/2026
|
|
| Vanguard Group Inc 13G/A Amendment 2 | 0% |
3/27/2026
Event 3/13/2026
|
|
|
Perceptive Advisors LLC
13G/A
Amendment 1
|
7.2% |
2/17/2026
Event 12/31/2025
|
|
| Perceptive Advisors LLC | 7.2% | ||
| Joseph Edelman | 7.2% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 7.2% | ||
|
Orbis Investment Management Ltd
13G
|
5.0% |
2/17/2026
Event 12/31/2025
|
|
| Orbis Investment Management Ltd | 5.0% | ||
| Allan Gray Australia Pty Ltd | 0% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 7
|
6.1% |
2/17/2026
Event 12/31/2025
|
|
| Point72 Asset Management, L.P. | 5.9% | ||
| Point72 Capital Advisors, Inc. | 5.9% | ||
| Point72 Biotech Private Investments, LLC | 0.3% | ||
| Differentiated Ventures Investments, LLC | 0.3% | ||
| 72 Investment Holdings, LLC | 0.3% | ||
| Steven A. Cohen | 6.1% | ||
|
Adage Capital Management, L.P.
13G/A
Amendment 4
|
3.8% |
2/12/2026
Event 12/31/2025
|
|
| Adage Capital Management, L.P. | 3.8% | ||
| Robert Atchinson | 3.8% | ||
| Phillip Gross | 3.8% | ||
|
FMR LLC
13G
|
5.4% |
2/5/2026
Event 12/31/2025
|
|
| FMR LLC | 5.4% | ||
| Abigail P. Johnson | 5.4% | ||
|
Janus Henderson Group PLC
13G/A
Amendment 3
|
12.3% |
11/14/2025
Event 9/30/2025
|
|
| Janus Henderson Group PLC | 12.3% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 6.2% | ||
|
Cormorant Asset Management, LP
13G/A
Amendment 6
|
4.0% |
11/14/2025
Event 9/30/2025
|
|
| Cormorant Asset Management, LP | 4.0% | ||
| Bihua Chen | 4.0% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 6
|
9.6% |
11/14/2025
Event 9/30/2025
|
|
| Point72 Asset Management, L.P. | 9.3% | ||
| Point72 Capital Advisors, Inc. | 9.3% | ||
| Point72 Biotech Private Investments, LLC | 0.3% | ||
| Differentiated Ventures Investments, LLC | 0.3% | ||
| 72 Investment Holdings, LLC | 0.3% | ||
| Steven A. Cohen | 9.6% | ||
| Price T Rowe Associates Inc /MD/ 13G/A Amendment 1 | 4.8% |
11/14/2025
Event 9/30/2025
|
|
|
Morgan Stanley
13G/A
Amendment 1
|
2.9% |
11/7/2025
Event 9/30/2025
|
|
| Morgan Stanley | 2.9% | ||
| Morgan Stanley Capital Services LLC | 1.4% | ||
|
Adage Capital Management, L.P.
13G/A
Amendment 3
|
5.3% |
11/3/2025
Event 10/31/2025
|
|
| Adage Capital Management, L.P. | 5.3% | ||
| Robert Atchinson | 5.3% | ||
| Phillip Gross | 5.3% | ||
|
Adage Capital Management, L.P.
13G/A
Amendment 2
|
11.3% |
9/2/2025
Event 8/31/2025
|
|
| Adage Capital Management, L.P. | 11.3% | ||
| Robert Atchinson | 11.3% | ||
| Phillip Gross | 11.3% | ||
|
Janus Henderson Group PLC
13G/A
Amendment 2
|
12.4% |
8/14/2025
Event 6/30/2025
|
|
| Janus Henderson Group PLC | 12.4% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.8% | ||
|
Cormorant Asset Management, LP
13G/A
Amendment 5
|
7.7% |
8/14/2025
Event 6/30/2025
|
|
| Cormorant Asset Management, LP | 7.7% | ||
| Bihua Chen | 7.7% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 5
|
7.3% |
8/14/2025
Event 6/30/2025
|
|
| Point72 Asset Management, L.P. | 7.0% | ||
| Point72 Capital Advisors, Inc. | 7.0% | ||
| Point72 Biotech Private Investments, LLC | 0.3% | ||
| Differentiated Ventures Investments, LLC | 0.3% | ||
| 72 Investment Holdings, LLC | 0.3% | ||
| Steven A. Cohen | 7.3% | ||
|
Adage Capital Management, L.P.
13G/A
Amendment 1
|
9.7% |
8/12/2025
Event 6/30/2025
|
|
| Adage Capital Management, L.P. | 9.7% | ||
| Robert Atchinson | 9.7% | ||
| Phillip Gross | 9.7% | ||
|
Soleus Capital Master Fund, L.P.
13G/A
Amendment 1
|
4.6% |
8/5/2025
Event 6/30/2025
|
|
| Soleus Capital Master Fund, L.P. | 4.6% | ||
| Soleus Capital, LLC | 4.6% | ||
| Soleus Capital Group, LLC | 4.6% | ||
| Soleus Capital Management, L.P. | 4.6% | ||
| Soleus GP, LLC | 4.6% | ||
| Guy Levy | 4.6% | ||
|
Perceptive Advisors LLC
13G
|
6.7% |
7/22/2025
Event 7/15/2025
|
|
| Perceptive Advisors LLC | 6.7% | ||
| Joseph Edelman | 6.7% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 6.7% | ||
|
Janus Henderson Group PLC
13G/A
Amendment 1
|
11.3% |
6/6/2025
Event 5/30/2025
|
|
| Janus Henderson Group PLC | 11.3% | ||
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.5% | ||
|
Venrock Healthcare Capital Partners III, L.P.
13G/A
Amendment 4
|
4.9% |
5/15/2025
Event 3/31/2025
|
|
| Venrock Healthcare Capital Partners III, L.P. | 4.9% | ||
| VHCP Co-Investment Holdings III, LLC | 4.9% | ||
| Venrock Healthcare Capital Partners EG, L.P. | 4.9% | ||
| VHCP Management III, LLC | 4.9% | ||
| VHCP Management EG, LLC | 4.9% | ||
| Nimish Shah | 4.9% | ||
| Bong Y Koh | 4.9% | ||
|
Cormorant Asset Management, LP
13G/A
Amendment 4
|
8.6% |
5/15/2025
Event 3/31/2025
|
|
| Cormorant Asset Management, LP | 8.6% | ||
| Bihua Chen | 8.6% | ||
|
Perceptive Advisors LLC
13G/A
Amendment 2
|
4.8% |
5/15/2025
Event 3/31/2025
|
|
| Perceptive Advisors LLC | 4.8% | ||
| Joseph Edelman | 4.8% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 4.8% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 4
|
5.8% |
5/15/2025
Event 3/31/2025
|
|
| Point72 Asset Management, L.P. | 5.5% | ||
| Point72 Capital Advisors, Inc. | 5.5% | ||
| Point72 Biotech Private Investments, LLC | 0.3% | ||
| Differentiated Ventures Investments, LLC | 0.3% | ||
| 72 Investment Holdings, LLC | 0.3% | ||
| Steven A. Cohen | 5.8% | ||
| Janus Henderson Group PLC 13G | 7.6% |
5/14/2025
Event 3/31/2025
|
|
| Capital Research Global Investors 13G/A Amendment 1 | 4.2% |
5/13/2025
Event 3/31/2025
|
|
|
Adage Capital Management, L.P.
13G
|
8.6% |
5/12/2025
Event 3/31/2025
|
|
| Adage Capital Management, L.P. | 8.6% | ||
| Robert Atchinson | 8.6% | ||
| Phillip Gross | 8.6% | ||
|
Soleus Capital Master Fund, L.P.
13G
|
5.0% |
3/19/2025
Event 3/18/2025
|
|
| Soleus Capital Master Fund, L.P. | 5.0% | ||
| Soleus Capital, LLC | 5.0% | ||
| Soleus Capital Group, LLC | 5.0% | ||
| Soleus Capital Management, L.P. | 5.0% | ||
| Soleus GP, LLC | 5.0% | ||
| Guy Levy | 5.0% | ||
|
Venrock Healthcare Capital Partners III, L.P.
13G/A
Amendment 3
|
6.1% |
2/14/2025
Event 12/31/2024
|
|
| Venrock Healthcare Capital Partners III, L.P. | 6.1% | ||
| VHCP Co-Investment Holdings III, LLC | 6.1% | ||
| Venrock Healthcare Capital Partners EG, L.P. | 6.1% | ||
| VHCP Management III, LLC | 6.1% | ||
| VHCP Management EG, LLC | 6.1% | ||
| Nimish Shah | 6.1% | ||
| Bong Y Koh | 6.1% | ||
|
Cormorant Asset Management, LP
13G/A
Amendment 3
|
9.1% |
2/14/2025
Event 12/31/2024
|
|
| Cormorant Asset Management, LP | 9.1% | ||
| Bihua Chen | 9.1% | ||
|
Perceptive Advisors LLC
13G/A
Amendment 1
|
9.5% |
2/14/2025
Event 12/31/2024
|
|
| Perceptive Advisors LLC | 9.5% | ||
| Joseph Edelman | 9.5% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 9.5% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 3
|
6.3% |
2/14/2025
Event 12/31/2024
|
|
| Point72 Asset Management, L.P. | 5.9% | ||
| Point72 Capital Advisors, Inc. | 5.9% | ||
| Point72 Biotech Private Investments, LLC | 0.3% | ||
| Differentiated Ventures Investments, LLC | 0.3% | ||
| 72 Investment Holdings, LLC | 0.3% | ||
| Steven A. Cohen | 6.3% | ||
|
Morgan Stanley
13G
|
6.2% |
2/5/2025
Event 12/31/2024
|
|
| Morgan Stanley | 6.2% | ||
| Morgan Stanley Capital Services LLC | 5.6% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 4 | 689 | $201 k |
| 2026 Q2 | 334 | 42.6 M | $11.3 B |
| 2026 Q1 | 316 | 31.9 M | $10.3 B |
| 2025 Q4 | 276 | 29.5 M | $8.69 B |
| 2025 Q3 | 170 | 24.7 M | $1.31 B |
| 2025 Q2 | 163 | 24.2 M | $1.02 B |
| 2025 Q1 | 170 | 23.5 M | $889 M |
| 2024 Q4 | 179 | 21.7 M | $1.67 B |
| 2024 Q3 | 151 | 18.9 M | $1.09 B |
| 2024 Q2 | 129 | 18.6 M | $770 M |
| 2024 Q1 | 122 | 16.2 M | $987 M |
| 2023 Q4 | 64 | 7.92 M | $176 M |