Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 501575104 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
| Price T Rowe Associates Inc /MD/ 13G/A Amendment 8 | 10.7% |
9/8/2026
Event 8/31/2026
|
|
| Price T Rowe Associates Inc /MD/ 13G/A Amendment 7 | 8.6% |
8/14/2026
Event 6/30/2026
|
|
|
Atlas Venture Fund X, L.P.
13G/A
Amendment 5
|
2.9% |
8/13/2026
Event 6/30/2026
|
|
| Atlas Venture Fund X, L.P. | 2.9% | ||
| Atlas Venture Associates X, L.P. | 2.9% | ||
| Atlas Venture Associates X, LLC | 2.9% | ||
| Atlas Venture Opportunity Fund I, L.P. | 0.6% | ||
| Atlas Venture Associates Opportunity I, L.P. | 0.6% | ||
| Atlas Venture Associates Opportunity I, LLC | 0.6% | ||
|
Biotechnology Value Fund L P
13D/A
Amendment 6
|
6.3% |
6/26/2026
Event 6/26/2026
|
|
| Biotechnology Value Fund L P | 3.3% | ||
| BVF I GP LLC | 3.3% | ||
| Biotechnology Value Fund II LP | 2.6% | ||
| BVF II GP LLC | 2.6% | ||
| Biotechnology Value Trading Fund OS LP | 0.4% | ||
| BVF Partners OS Ltd. | 0.4% | ||
| BVF GP Holdings LLC | 5.8% | ||
| BVF Partners L P/IL | 6.3% | ||
| BVF Inc/IL | 6.3% | ||
| Lampert Mark N | 6.3% | ||
| Hrustanovic Gorjan | 0.1% | ||
| T. Rowe Price Investment Management, Inc. 13G | 6.7% |
5/15/2026
Event 3/31/2026
|
|
|
Wellington Management Group LLP
13G/A
Amendment 8
|
4.8% |
5/15/2026
Event 3/31/2026
|
|
| Wellington Management Group LLP | 4.8% | ||
| Wellington Group Holdings LLP | 4.8% | ||
| Wellington Investment Advisors Holdings LLP | 4.8% | ||
|
FMR LLC
13G/A
Amendment 4
|
14.3% |
5/6/2026
Event 3/31/2026
|
|
| FMR LLC | 14.3% | ||
| Abigail P. Johnson | 14.3% | ||
| Vanguard Group Inc 13G/A Amendment 4 | 0% |
3/27/2026
Event 3/13/2026
|
|
|
Wellington Management Group LLP
13G/A
Amendment 7
|
5.5% |
2/10/2026
Event 12/31/2025
|
|
| Wellington Management Group LLP | 5.5% | ||
| Wellington Group Holdings LLP | 5.5% | ||
| Wellington Investment Advisors Holdings LLP | 5.5% | ||
| Wellington Management Company LLP | 5.3% | ||
|
FMR LLC
13G/A
Amendment 3
|
11.2% |
1/8/2026
Event 12/31/2025
|
|
| FMR LLC | 11.2% | ||
| Abigail P. Johnson | 11.2% | ||
|
Biotechnology Value Fund L P
13D/A
Amendment 5
|
8.5% |
12/15/2025
Event 12/11/2025
|
|
| Biotechnology Value Fund L P | 4.4% | ||
| BVF I GP LLC | 4.4% | ||
| Biotechnology Value Fund II LP | 3.4% | ||
| BVF II GP LLC | 3.4% | ||
| Biotechnology Value Trading Fund OS LP | 0.5% | ||
| BVF Partners OS Ltd. | 0.5% | ||
| BVF GP Holdings LLC | 7.8% | ||
| BVF Partners L P/IL | 8.5% | ||
| BVF Inc/IL | 8.5% | ||
| Lampert Mark N | 8.5% | ||
| Hrustanovic Gorjan | 0.1% | ||
|
Baker Bros. Advisors LP
13D/A
Amendment 3
|
10.9% |
12/11/2025
Event 12/9/2025
|
|
| Baker Bros. Advisors LP | 10.9% | ||
| Baker Bros. Advisors (GP) LLC | 10.9% | ||
| Julian C. Baker | 10.9% | ||
| Felix J. Baker | 10.9% | ||
| Price T Rowe Associates Inc /MD/ 13G/A Amendment 6 | 7.1% |
11/14/2025
Event 9/30/2025
|
|
|
FMR LLC
13G/A
Amendment 2
|
8.2% |
11/5/2025
Event 9/30/2025
|
|
| FMR LLC | 8.2% | ||
| Abigail P. Johnson | 8.2% | ||
|
Wellington Management Group LLP
13G/A
Amendment 6
|
7.7% |
8/12/2025
Event 6/30/2025
|
|
| Wellington Management Group LLP | 7.7% | ||
| Wellington Group Holdings LLP | 7.7% | ||
| Wellington Investment Advisors Holdings LLP | 7.7% | ||
| Wellington Management Company LLP | 7.4% | ||
| BlackRock, Inc. 13G/A Amendment 3 | 5.4% |
7/17/2025
Event 6/30/2025
|
|
|
Baker Bros. Advisors LP
13D/A
Amendment 2
|
9.5% |
6/30/2025
Event 6/26/2025
|
|
| Baker Bros. Advisors LP | 9.5% | ||
| Baker Bros. Advisors (GP) LLC | 9.5% | ||
| Julian C. Baker | 9.5% | ||
| Felix J. Baker | 9.5% | ||
|
Wellington Management Group LLP
13G/A
Amendment 5
|
9.2% |
5/12/2025
Event 3/31/2025
|
|
| Wellington Management Group LLP | 9.2% | ||
| Wellington Group Holdings LLP | 9.2% | ||
| Wellington Investment Advisors Holdings LLP | 9.2% | ||
| Wellington Management Company LLP | 9.0% | ||
|
FMR LLC
13G/A
Amendment 1
|
6.8% |
5/12/2025
Event 3/31/2025
|
|
| FMR LLC | 6.8% | ||
| Abigail P. Johnson | 6.8% | ||
| Vanguard Group Inc 13G/A Amendment 3 | 8.1% |
4/30/2025
Event 3/31/2025
|
|
|
Wellington Management Group LLP
13G/A
Amendment 4
|
8.2% |
2/10/2025
Event 12/31/2024
|
|
| Wellington Management Group LLP | 8.2% | ||
| Wellington Group Holdings LLP | 8.2% | ||
| Wellington Investment Advisors Holdings LLP | 8.2% | ||
| Wellington Management Company LLP | 8.0% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 17 | 21.7 k | $2.15 M |
| 2026 Q2 | 294 | 103 M | $11.1 B |
| 2026 Q1 | 265 | 96.3 M | $8.01 B |
| 2025 Q4 | 270 | 90.0 M | $7.00 B |
| 2025 Q3 | 220 | 81.1 M | $4.59 B |
| 2025 Q2 | 222 | 79.0 M | $3.45 B |
| 2025 Q1 | 188 | 72.9 M | $2.00 B |
| 2024 Q4 | 190 | 71.7 M | $2.88 B |
| 2024 Q3 | 185 | 69.2 M | $3.27 B |
| 2024 Q2 | 163 | 68.2 M | $2.03 B |
| 2024 Q1 | 173 | 68.8 M | $2.77 B |
| 2023 Q4 | 145 | 62.1 M | $1.58 B |
| 2023 Q3 | 126 | 57.4 M | $797 M |
| 2023 Q2 | 134 | 58.4 M | $1.34 B |
| 2023 Q1 | 136 | 56.9 M | $1.68 B |
| 2022 Q4 | 135 | 59.1 M | $1.47 B |
| 2022 Q3 | 136 | 52.9 M | $1.15 B |
| 2022 Q2 | 104 | 49.4 M | $974 M |
| 2022 Q1 | 136 | 45.8 M | $1.94 B |
| 2021 Q4 | 139 | 43.7 M | $2.77 B |
| 2021 Q3 | 121 | 34.6 M | $2.04 B |
| 2021 Q2 | 115 | 26.5 M | $1.29 B |
| 2021 Q1 | 100 | 22.8 M | $887 M |
| 2020 Q4 | 77 | 20.3 M | $1.25 B |
| 2020 Q3 | 53 | 16.8 M | $543 M |