Investors who own more than 5% of a class must file a Schedule 13D or 13G. Each filer's latest filing for 483497103 since 12/18/2024, largest first.
| Filer | % of Class | Filed | ||
|---|---|---|---|---|
| Capital World Investors 13G/A | 6.4% |
5/13/2025
Event 3/31/2025
|
||
|
SilverArc Capital Management, LLC
13G
|
5.6% |
5/13/2026
Event 3/31/2026
|
||
| SilverArc Capital Management, LLC | 5.6% | |||
| Devesh Gandhi | 5.6% | |||
| Under 5%, checked the "5 percent or less" box, or amended by a later filing (6) | ||||
|
Glazer Capital, LLC
13G
|
4.9% |
6/10/2026
Event 6/3/2026
|
||
| Glazer Capital, LLC | 4.9% | |||
| Paul J. Glazer | 4.9% | |||
|
Point72 Asset Management, L.P.
13G/A
|
4.2% |
5/15/2026
Event 3/31/2026
|
||
| Point72 Asset Management, L.P. | 4.2% | |||
| Point72 Capital Advisors, Inc. | 4.2% | |||
| Steven A. Cohen | 4.2% | |||
|
Millennium Management LLC
13G/A
|
3.7% |
5/1/2026
Event 3/31/2026
|
||
| Integrated Core Strategies (US) LLC | 3.0% | |||
| Millennium Management LLC | 3.7% | |||
| Millennium Group Management LLC | 3.7% | |||
| Israel A. Englander | 3.7% | |||
|
Frazier Life Sciences Public Fund, L.P.
13D/A
|
2.3% |
5/21/2026
Event 5/19/2026
|
||
| Frazier Life Sciences Public Fund, L.P. | 2.3% | |||
| FHMLSP, L.P. | 2.3% | |||
| FHMLSP, L.L.C. | 2.3% | |||
| Frazier Life Sciences X, L.P. | 0.8% | |||
| FHMLS X, L.P. | 0.8% | |||
| FHMLS X, L.L.C. | 0.8% | |||
| Frazier Life Sciences XI, L.P. | 0.3% | |||
| FHMLS XI, L.P. | 0.3% | |||
| FHMLS XI, L.L.C. | 0.8% | |||
| Frazier Life Sciences XII, L.P. | 0% | |||
| FHMLS XII, L.P. | 0% | |||
| FHMLS XII, L.L.C. | 0% | |||
| James N. Topper | 0.8% | |||
| Patrick J. Heron | 0.8% | |||
|
Vestal Point Capital, LP
13G/A
|
1.5% |
11/14/2025
Event 9/30/2025
|
||
| Vestal Point Capital, LP | 1.5% | |||
| Ryan Wilder | 1.5% | |||
|
Tang Capital Management LLC
13G/A
|
0% |
8/14/2026
Event 6/30/2026
|
||
| Tang Capital Management, LLC | 0% | |||
| Kevin Tang | 0% | |||
| Tang Capital Partners, LP | 0% | |||
| Tang Capital Partners International, LP | 0% | |||
| Tang Capital Partners III, Inc | 0% | |||
| Tang Capital Partners IV, Inc | 0% | |||
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q2 | 1 | 7.00 | $189.00 |
| 2026 Q1 | 195 | 69.3 M | $1.39 B |
| 2025 Q4 | 168 | 67.0 M | $1.08 B |
| 2025 Q3 | 153 | 58.6 M | $714 M |
| 2025 Q2 | 152 | 54.5 M | $617 M |
| 2025 Q1 | 142 | 54.9 M | $641 M |
| 2024 Q4 | 135 | 55.3 M | $468 M |
| 2024 Q3 | 130 | 48.5 M | $562 M |
| 2024 Q2 | 127 | 48.6 M | $573 M |
| 2024 Q1 | 138 | 48.0 M | $569 M |
| 2023 Q4 | 113 | 37.6 M | $460 M |
| 2023 Q3 | 113 | 36.3 M | $350 M |
| 2023 Q2 | 100 | 34.5 M | $310 M |
| 2023 Q1 | 91 | 33.7 M | $265 M |
| 2022 Q4 | 97 | 35.0 M | $239 M |
| 2022 Q3 | 101 | 25.6 M | $372 M |
| 2022 Q2 | 95 | 24.3 M | $239 M |
| 2022 Q1 | 94 | 24.3 M | $364 M |
| 2021 Q4 | 103 | 23.8 M | $315 M |
| 2021 Q3 | 113 | 23.4 M | $408 M |
| 2021 Q2 | 120 | 24.3 M | $583 M |
| 2021 Q1 | 127 | 23.6 M | $605 M |
| 2020 Q4 | 97 | 16.7 M | $310 M |
| 2020 Q3 | 66 | 16.2 M | $204 M |
| 2020 Q2 | 74 | 16.0 M | $194 M |
| 2020 Q1 | 72 | 15.9 M | $122 M |
| 2019 Q4 | 76 | 13.9 M | $247 M |
| 2019 Q3 | 79 | 13.7 M | $159 M |
| 2019 Q2 | 79 | 14.8 M | $329 M |
| 2019 Q1 | 71 | 13.9 M | $399 M |
| 2018 Q4 | 59 | 13.4 M | $263 M |
| 2018 Q3 | 51 | 12.7 M | $278 M |
| 2018 Q2 | 27 | 6.34 M | $51.5 M |
| 2018 Q1 | 26 | 6.55 M | $62.0 M |
| 2017 Q4 | 24 | 6.48 M | $63.2 M |
| 2017 Q3 | 18 | 7.72 M | $52.2 M |
| 2017 Q2 | 18 | 7.37 M | $54.1 M |
| 2017 Q1 | 21 | 7.59 M | $59.2 M |
| 2016 Q4 | 21 | 7.33 M | $51.5 M |