Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 27966L306 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Stonepine Capital Management, LLC
13G
|
6.9% |
8/26/2026
Event 8/20/2026
|
|
| Stonepine Capital Management, LLC | 6.9% | ||
| Stonepine Capital, L.P. | 6.9% | ||
| Stonepine GP, LLC | 6.9% | ||
| Jon M. Plexico | 6.9% | ||
|
Pardeep Nijhawan
13D/A
Amendment 11
|
16.3% |
8/25/2026
Event 8/21/2026
|
|
| Pardeep Nijhawan Medicine Professional Corporation | 7.8% | ||
| The Digestive Health Clinic Inc. | 0.2% | ||
| 1968160 Ontario Inc. | 0.4% | ||
| The New Nijhawan Family Trust 2015 | 0.2% | ||
| Pardeep Nijhawan | 16.3% | ||
|
Velan Capital Investment Management LP
13D/A
Amendment 2
|
10.0% |
8/25/2026
Event 8/21/2026
|
|
| Velan Capital Master Fund LP | 8.0% | ||
| Velan Horizon Fund LP | 0.2% | ||
| Velan Capital Opportunity Fund II LLC | 1.9% | ||
| Velan Horizon GP LLC | 0.2% | ||
| Velan Capital Holdings LLC | 9.8% | ||
| Velan Capital Investment Management LP | 10.0% | ||
| Velan Capital Management LLC | 10.0% | ||
| Morgan Adam | 10.0% | ||
| Venkataraman Balaji | 10.0% | ||
|
Integrated Core Strategies (US) LLC
13G
|
5.4% |
6/18/2026
Event 6/11/2026
|
|
| Integrated Core Strategies (US) LLC | 5.4% | ||
| Millennium Management LLC | 5.4% | ||
| Millennium Group Management LLC | 5.4% | ||
| Israel A. Englander | 5.4% | ||
|
Pardeep Nijhawan
13D/A
Amendment 10
|
20.0% |
6/16/2026
Event 6/16/2026
|
|
| Pardeep Nijhawan Medicine Professional Corporation | 11.2% | ||
| The Digestive Health Clinic Inc. | 0.3% | ||
| 1968160 Ontario Inc. | 0.6% | ||
| The New Nijhawan Family Trust 2015 | 0.3% | ||
| Pardeep Nijhawan | 20.0% | ||
|
Nantahala Capital Management, LLC
13G/A
Amendment 2
|
0% |
5/15/2026
Event 3/31/2026
|
|
| Nantahala Capital Management, LLC | 0% | ||
| Wilmot B. Harkey | 0% | ||
| Daniel Mack | 0% | ||
|
Rubric Capital Management LP
13G
|
7.7% |
5/15/2026
Event 3/31/2025
|
|
| Rubric Capital Management LP | 7.7% | ||
| David Rosen | 7.7% | ||
|
Stonepine Capital Management, LLC
13G/A
Amendment 1
|
0.3% |
5/15/2026
Event 3/31/2026
|
|
| Stonepine Capital Management, LLC | 0.3% | ||
| Stonepine Capital, L.P. | 0.3% | ||
| Stonepine GP, LLC | 0.3% | ||
| Jon M. Plexico | 0.3% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 1
|
0% |
5/15/2026
Event 3/31/2026
|
|
| Point72 Asset Management, L.P. | 0% | ||
| Point72 Capital Advisors, Inc. | 0% | ||
| Steven A. Cohen | 0% | ||
|
Sirenia Capital Management LP
13G
|
7.2% |
5/15/2026
Event 3/31/2026
|
|
| Sirenia Capital Management LP | 7.2% | ||
| Alex Silverstein | 7.2% | ||
|
Perceptive Advisors LLC
13G
|
6.7% |
3/16/2026
Event 3/9/2026
|
|
| Perceptive Advisors LLC | 6.7% | ||
| Joseph Edelman | 6.7% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 6.7% | ||
|
Point72 Asset Management, L.P.
13G
|
7.2% |
3/3/2026
Event 2/24/2026
|
|
| Point72 Asset Management, L.P. | 7.2% | ||
| Point72 Capital Advisors, Inc. | 7.2% | ||
| Steven A. Cohen | 7.2% | ||
|
Pardeep Nijhawan
13D/A
Amendment 9
|
20.0% |
3/2/2026
Event 2/26/2026
|
|
| Pardeep Nijhawan Medicine Professional Corporation | 11.9% | ||
| The Digestive Health Clinic Inc. | 0.4% | ||
| 1968160 Ontario Inc. | 0.6% | ||
| The New Nijhawan Family Trust 2015 | 0.4% | ||
| Pardeep Nijhawan | 20.0% | ||
|
Velan Capital Investment Management LP
13D/A
Amendment 1
|
10.0% |
3/2/2026
Event 2/26/2026
|
|
| Velan Capital Master Fund LP | 6.8% | ||
| Velan Horizon Fund LP | 0.2% | ||
| Velan Capital Opportunity Fund II LLC | 3.0% | ||
| Velan Horizon GP LLC | 0.2% | ||
| Velan Capital Holdings LLC | 9.8% | ||
| Velan Capital Investment Management LP | 10.0% | ||
| Velan Capital Management LLC | 10.0% | ||
| Morgan Adam | 10.0% | ||
| Venkataraman Balaji | 10.0% | ||
|
Nantahala Capital Management, LLC
13G/A
Amendment 1
|
10.0% |
2/13/2026
Event 12/31/2025
|
|
| Nantahala Capital Management, LLC | 10.0% | ||
| Wilmot B. Harkey | 10.0% | ||
| Daniel Mack | 10.0% | ||
|
Nantahala Capital Management, LLC
13G
|
10.0% |
5/15/2025
Event 3/31/2025
|
|
| Nantahala Capital Management, LLC | 10.0% | ||
| Wilmot B. Harkey | 10.0% | ||
| Daniel Mack | 10.0% | ||
|
Stonepine Capital Management, LLC
13G
|
9.9% |
2/25/2025
Event 2/13/2025
|
|
| Stonepine Capital Management, LLC | 9.9% | ||
| Stonepine Capital, L.P. | 9.9% | ||
| Stonepine GP, LLC | 9.9% | ||
| Jon M. Plexico | 9.9% | ||
| Thomas A. Satterfield, Jr. 13G/A Amendment 2 | 0% |
2/18/2025
Event 2/13/2025
|
|
|
Velan Capital Investment Management LP
13D
|
10.0% |
2/18/2025
Event 2/12/2025
|
|
| Velan Capital Master Fund LP | 6.2% | ||
| Velan Horizon Fund LP | 0.2% | ||
| Velan Capital Opportunity Fund II LLC | 3.6% | ||
| Velan Horizon GP LLC | 0.2% | ||
| Velan Capital Holdings LLC | 9.8% | ||
| Velan Capital Investment Management LP | 10.0% | ||
| Velan Capital Management LLC | 10.0% | ||
| Morgan Adam | 10.0% | ||
| Venkataraman Balaji | 10.0% | ||
|
Pardeep Nijhawan
13D/A
Amendment 8
|
20.0% |
2/14/2025
Event 2/12/2025
|
|
| Pardeep Nijhawan Medicine Professional Corporation | 14.5% | ||
| The Digestive Health Clinic Inc. | 0.5% | ||
| 1968160 Ontario Inc. | 0.8% | ||
| The New Nijhawan Family Trust 2015 | 0.7% | ||
| Pardeep Nijhawan | 20.0% | ||
| Thomas A. Satterfield, Jr. 13G/A Amendment 1 | 6.7% |
2/12/2025
Event 12/31/2024
|
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q2 | 33 | 3.75 M | $31.0 M |
| 2026 Q1 | 28 | 2.64 M | $13.8 M |
| 2025 Q4 | 22 | 3.05 M | $4.34 M |
| 2025 Q3 | 23 | 2.88 M | $7.10 M |
| 2025 Q2 | 22 | 2.11 M | $4.28 M |
| 2025 Q1 | 21 | 2.82 M | $6.89 M |
| 2024 Q4 | 18 | 208 k | $350 k |
| 2024 Q3 | 19 | 161 k | $718 k |
| 2024 Q2 | 19 | 151 k | $645 k |
| 2024 Q1 | 20 | 108 k | $451 k |
| 2023 Q4 | 21 | 111 k | $507 k |