Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 13463J101 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
5AM Ventures VI, L.P.
13D/A
Amendment 3
|
9.9% |
8/31/2026
Event 8/27/2026
|
|
| 5AM Ventures VI, L.P. | 3.2% | ||
| 5AM Partners VI, LLC | 3.2% | ||
| 5AM Ventures VII, L.P. | 6.3% | ||
| 5AM Partners VII, LLC | 6.3% | ||
| 5AM Opportunities II, L.P. | 0.5% | ||
| 5AM Opportunities II (GP), LLC | 0.5% | ||
| Andrew J. Schwab | 9.9% | ||
| Kush Parmar | 9.9% | ||
|
Polaris Management Co. VII, L.L.C.
13D/A
Amendment 2
|
6.3% |
8/19/2026
Event 8/13/2026
|
|
| Polaris Management Co. VII, L.L.C. | 4.8% | ||
| Polaris Partners VII, L.P. | 4.5% | ||
| Polaris Entrepreneurs' Fund VII, L.P. | 0.3% | ||
| Polaris Partners GP X, L.L.C. | 1.4% | ||
| Polaris Partners X, L.P. | 1.4% | ||
| Amir Nashat | 6.3% | ||
| Brian Chee | 1.4% | ||
| Amy Schulman | 1.4% | ||
|
Balyasny Asset Management L.P.
13G/A
Amendment 1
|
4.99% |
8/14/2026
Event 6/30/2026
|
|
| Balyasny Asset Management L.P. | 4.99% | ||
| Bam GP LLC | 4.99% | ||
| Balyasny Asset Management Holdings LP | 4.99% | ||
| Dames GP LLC | 4.99% | ||
| Dmitry Balyasny | 4.99% | ||
|
Trails Edge Capital Partners, LP
13G
|
6.0% |
8/10/2026
Event 8/3/2026
|
|
| Trails Edge Capital Partners, LP | 6.0% | ||
| Trails Edge Biotechnology Master Fund, LP | 6.0% | ||
| Ortav Yehudai | 6.0% | ||
|
5AM Ventures VI, L.P.
13D/A
Amendment 2
|
9.9% |
8/5/2026
Event 8/3/2026
|
|
| 5AM Ventures VI, L.P. | 4.2% | ||
| 5AM Partners VI, LLC | 4.2% | ||
| 5AM Ventures VII, L.P. | 5.3% | ||
| 5AM Partners VII, LLC | 5.3% | ||
| 5AM Opportunities II, L.P. | 0.5% | ||
| 5AM Opportunities II (GP), LLC | 0.5% | ||
| Andrew J. Schwab | 9.9% | ||
| Kush Parmar | 9.9% | ||
|
Balyasny Asset Management L.P.
13G
|
5.1% |
5/15/2026
Event 3/31/2026
|
|
| Balyasny Asset Management L.P. | 5.1% | ||
| Bam GP LLC | 5.1% | ||
| Balyasny Asset Management Holdings LP | 5.1% | ||
| Dames GP LLC | 5.1% | ||
| Dmitry Balyasny | 5.1% | ||
|
Enavate Sciences GP, LLC
13D/A
Amendment 3
|
4.8% |
3/11/2026
Event 3/9/2026
|
|
| Enavate Sciences GP, LLC | 4.8% | ||
| Everest Aggregator, LP | 4.8% | ||
|
Vivo Opportunity Fund Holdings, L.P.
13G/A
Amendment 1
|
7.4% |
2/13/2026
Event 12/31/2025
|
|
| Vivo Opportunity Fund Holdings, L.P. | 7.4% | ||
| Vivo Opportunity, LLC | 7.4% | ||
| Vivo Opportunity Cayman Fund, L.P. | 0.8% | ||
| Vivo Opportunity Cayman, LLC | 0.8% | ||
|
FMR LLC
13G/A
Amendment 2
|
9.5% |
2/5/2026
Event 12/31/2025
|
|
| FMR LLC | 9.5% | ||
| Abigail P. Johnson | 9.5% | ||
| Janus Henderson Group PLC 13G | 12.2% |
1/8/2026
Event 12/31/2025
|
|
|
Enavate Sciences GP, LLC
13D/A
Amendment 2
|
6.0% |
12/23/2025
Event 12/19/2025
|
|
| Enavate Sciences GP, LLC | 6.0% | ||
| Everest Aggregator, LP | 6.0% | ||
|
Coastlands Capital LP
13G/A
Amendment 1
|
10.0% |
12/11/2025
Event 9/10/2025
|
|
| Coastlands Capital LP | 10.0% | ||
| Coastlands Capital Partners LP | 10.0% | ||
| Coastlands Capital GP LLC | 10.0% | ||
| Coastlands Capital LLC | 10.0% | ||
| Matthew D. Perry | 10.0% | ||
|
Northpond Ventures II, LP
13G/A
Amendment 1
|
4.8% |
11/14/2025
Event 9/30/2025
|
|
| Northpond Ventures II, LP | 2.1% | ||
| Northpond Ventures II GP, LLC | 2.1% | ||
| Northpond Ventures III, LP | 1.6% | ||
| Northpond Ventures III GP, LLC | 1.6% | ||
| Northpond Ventures, LP | 1.0% | ||
| Northpond Ventures GP, LLC | 1.0% | ||
| Michael P. Rubin | 4.8% | ||
|
AH Bio Fund I, L.P.
13G/A
Amendment 1
|
4.5% |
11/14/2025
Event 9/30/2025
|
|
| AH Bio Fund I, L.P. | 3.4% | ||
| AH Equity Partners Bio I, L.L.C. | 3.4% | ||
| AH Bio Fund IV, L.P. | 1.2% | ||
| AH Equity Partners Bio IV, L.L.C. | 1.2% | ||
| Marc L. Andreessen | 4.5% | ||
| Benjamin A. Horowitz | 4.5% | ||
|
FMR LLC
13G/A
Amendment 1
|
6.7% |
11/7/2025
Event 10/31/2025
|
|
| FMR LLC | 6.7% | ||
| Abigail P. Johnson | 6.7% | ||
|
FMR LLC
13G
|
15.0% |
10/7/2025
Event 9/30/2025
|
|
| FMR LLC | 15.0% | ||
| Abigail P. Johnson | 15.0% | ||
|
HarbourVest Partners, LLC
13G/A
Amendment 1
|
2.7% |
10/1/2025
Event 9/30/2025
|
|
| HarbourVest Partners L.P. | 2.7% | ||
| HarbourVest Partners, LLC | 2.7% | ||
| SMRS-Tope LLC | 2.7% | ||
| HVST-Tope LLC | 2.7% | ||
|
Vivo Opportunity Fund Holdings, L.P.
13G
|
7.6% |
9/17/2025
Event 9/11/2025
|
|
| Vivo Opportunity Fund Holdings, L.P. | 7.6% | ||
| Vivo Opportunity, LLC | 7.6% | ||
| Vivo Opportunity Cayman Fund, L.P. | 0.8% | ||
| Vivo Opportunity Cayman, LLC | 0.8% | ||
|
Coastlands Capital LP
13G
|
10.0% |
9/16/2025
Event 9/10/2025
|
|
| Coastlands Capital LP | 10.0% | ||
| Coastlands Capital Partners LP | 10.0% | ||
| Coastlands Capital GP LLC | 10.0% | ||
| Coastlands Capital LLC | 10.0% | ||
| Matthew D. Perry | 10.0% | ||
|
Enavate Sciences GP, LLC
13D/A
Amendment 1
|
8.1% |
9/15/2025
Event 9/11/2025
|
|
| Enavate Sciences GP, LLC | 8.1% | ||
| Everest Aggregator, LP | 8.1% | ||
|
5AM Ventures VI, L.P.
13D/A
Amendment 1
|
12.5% |
9/11/2025
Event 9/9/2025
|
|
| 5AM Ventures VI, L.P. | 5.6% | ||
| 5AM Partners VI, LLC | 5.6% | ||
| 5AM Ventures VII, L.P. | 6.3% | ||
| 5AM Partners VII, LLC | 6.3% | ||
| 5AM Opportunities II, L.P. | 0.6% | ||
| 5AM Opportunities II (GP), LLC | 0.6% | ||
| Andrew J. Schwab | 12.5% | ||
| Kush Parmar | 12.5% | ||
|
Polaris Management Co. VII, L.L.C.
13D/A
Amendment 1
|
8.4% |
9/11/2025
Event 9/9/2025
|
|
| Polaris Management Co. VII, L.L.C. | 6.4% | ||
| Polaris Partners VII, L.P. | 6.0% | ||
| Polaris Entrepreneurs' Fund VII, L.P. | 0.4% | ||
| Polaris Partners GP X, L.L.C. | 1.9% | ||
| Polaris Partners X, L.P. | 1.9% | ||
| Amir Nashat | 8.4% | ||
| Brian Chee | 1.9% | ||
| Amy Schulman | 1.9% | ||
|
HarbourVest Partners, LLC
13G
|
6.3% |
5/14/2025
Event 12/31/2024
|
|
| HarbourVest Partners L.P. | 6.3% | ||
| HarbourVest Partners, LLC | 6.3% | ||
| SMRS-Tope LLC | 6.3% | ||
| HVST-Tope LLC | 6.3% |