Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 055477103 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
| T. Rowe Price Investment Management, Inc. 13G/A Amendment 2 | 4.2% |
10/7/2026
Event 9/30/2026
|
|
| Janus Henderson Group Ltd. 13G/A Amendment 1 | 4.8% |
8/13/2026
Event 6/30/2026
|
|
| BlackRock, Inc. 13G | 5.4% |
7/27/2026
Event 6/30/2026
|
|
| Janus Henderson Group PLC 13G | 5.1% |
5/15/2026
Event 3/31/2026
|
|
|
Deep Track Capital, LP
13G/A
Amendment 1
|
6.2% |
5/15/2026
Event 3/31/2026
|
|
| Deep Track Capital, LP | 6.2% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 6.2% | ||
| David Kroin | 6.2% | ||
|
Vestal Point Capital, LP
13G/A
Amendment 3
|
8.3% |
5/15/2026
Event 3/31/2026
|
|
| Vestal Point Capital, LP | 8.3% | ||
| Ryan Wilder | 8.3% | ||
|
Red Tree GP, LLC
13G/A
Amendment 1
|
4.8% |
5/8/2026
Event 3/31/2026
|
|
| Red Tree GP, LLC | 4.8% | ||
| Red Tree Venture Fund, L.P. | 4.8% | ||
| Heath Lukatch | 4.8% | ||
|
FMR LLC
13G/A
Amendment 2
|
3.2% |
5/6/2026
Event 3/31/2026
|
|
| FMR LLC | 3.2% | ||
| Abigail P. Johnson | 3.2% | ||
| T. Rowe Price Investment Management, Inc. 13G/A Amendment 1 | 10.1% |
4/8/2026
Event 3/31/2026
|
|
|
RA Capital Management, L.P.
13D/A
Amendment 1
|
11.5% |
3/2/2026
Event 2/26/2026
|
|
| RA Capital Management, L.P. | 11.5% | ||
| Peter Kolchinsky | 11.5% | ||
| Rajeev Shah | 11.5% | ||
| RA Capital Healthcare Fund, L.P. | 7.3% | ||
| T. Rowe Price Investment Management, Inc. 13G | 5.9% |
2/17/2026
Event 12/31/2025
|
|
|
Vestal Point Capital, LP
13G/A
Amendment 2
|
6.5% |
2/17/2026
Event 12/31/2025
|
|
| Vestal Point Capital, LP | 6.5% | ||
| Ryan Wilder | 6.5% | ||
|
Deep Track Capital, LP
13G
|
5.0% |
2/12/2026
Event 2/5/2026
|
|
| Deep Track Capital, LP | 5.0% | ||
| Deep Track Biotechnology Master Fund, Ltd. | 5.0% | ||
| David Kroin | 5.0% | ||
|
FMR LLC
13G/A
Amendment 1
|
6.1% |
2/5/2026
Event 12/31/2025
|
|
| FMR LLC | 6.1% | ||
| Abigail P. Johnson | 6.1% | ||
|
Vestal Point Capital, LP
13G/A
Amendment 1
|
9.2% |
8/14/2025
Event 6/30/2025
|
|
| Vestal Point Capital, LP | 9.2% | ||
| Ryan Wilder | 9.2% | ||
|
Invus Global Management, LLC
13G/A
Amendment 1
|
9.6% |
7/31/2025
Event 6/30/2025
|
|
| Invus Public Equities, L.P. | 8.9% | ||
| Invus Public Equities Advisors, LLC | 8.9% | ||
| Invus Global Management, LLC | 8.9% | ||
| Siren, L.L.C. | 8.9% | ||
| Avicenna Life Sci Master Fund LP | 0.7% | ||
| Avicenna Life Sci Master GP LLC | 0.7% | ||
| Ulys, L.L.C. | 0.7% | ||
| Raymond Debbane | 9.6% | ||
|
FMR LLC
13G
|
5.1% |
7/17/2025
Event 7/10/2025
|
|
| FMR LLC | 5.1% | ||
| Abigail P. Johnson | 5.1% | ||
|
FMR LLC
13G/A
Amendment 2
|
4.7% |
7/17/2025
Event 6/30/2025
|
|
| FMR LLC | 4.7% | ||
| Abigail P. Johnson | 4.7% | ||
|
Vestal Point Capital, LP
13G
|
5.1% |
5/15/2025
Event 3/31/2025
|
|
| Vestal Point Capital, LP | 5.1% | ||
| Ryan Wilder | 5.1% | ||
|
FMR LLC
13G/A
Amendment 1
|
6.6% |
5/12/2025
Event 3/31/2025
|
|
| FMR LLC | 6.6% | ||
| Abigail P. Johnson | 6.6% | ||
|
FMR LLC
13G
|
5.2% |
3/3/2025
Event 2/24/2025
|
|
| FMR LLC | 5.2% | ||
| Abigail P. Johnson | 5.2% | ||
|
FMR LLC
13G/A
Amendment 1
|
3.9% |
2/12/2025
Event 12/31/2024
|
|
| FMR LLC | 3.9% | ||
| Abigail P. Johnson | 3.9% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 4 | 2.04 k | $37.9 k |
| 2026 Q2 | 180 | 71.0 M | $2.11 B |
| 2026 Q1 | 152 | 68.9 M | $1.35 B |
| 2025 Q4 | 146 | 57.3 M | $964 M |
| 2025 Q3 | 116 | 50.2 M | $790 M |
| 2025 Q2 | 108 | 51.2 M | $475 M |
| 2025 Q1 | 94 | 48.6 M | $634 M |
| 2024 Q4 | 86 | 47.4 M | $825 M |
| 2024 Q3 | 72 | 36.4 M | $928 M |