Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 02157Q109 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Perceptive Advisors LLC
13G/A
Amendment 2
|
10.0% |
8/14/2026
Event 6/30/2026
|
|
| Perceptive Advisors LLC | 10.0% | ||
| Joseph Edelman | 10.0% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 10.0% | ||
|
Sirenia Capital Management LP
13G/A
Amendment 1
|
6.2% |
8/14/2026
Event 6/30/2026
|
|
| Sirenia Capital Management LP | 6.2% | ||
| Alex Silverstein | 6.2% | ||
|
Vestal Point Capital, LP
13G/A
Amendment 2
|
2.2% |
8/14/2026
Event 6/30/2026
|
|
| Vestal Point Capital, LP | 2.2% | ||
| Ryan Wilder | 2.2% | ||
| BlackRock, Inc. 13G | 6.0% |
7/27/2026
Event 6/30/2026
|
|
|
EcoR1 Capital, LLC
13G
|
5.8% |
7/20/2026
Event 7/13/2026
|
|
| EcoR1 Capital, LLC | 5.8% | ||
| Oleg Nodelman | 5.8% | ||
| EcoR1 Capital Fund Qualified, L.P. | 5.3% | ||
|
Commodore Capital LP
13G/A
Amendment 2
|
9.9% |
5/15/2026
Event 3/31/2026
|
|
| Commodore Capital LP | 9.9% | ||
| Commodore Capital Master LP | 9.9% | ||
| Robert Egen Atkinson | 9.9% | ||
| Michael Kramarz | 9.9% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 4
|
3.7% |
5/15/2026
Event 3/31/2026
|
|
| Point72 Asset Management, L.P. | 1.6% | ||
| Point72 Capital Advisors, Inc. | 1.6% | ||
| Point72 Biotech Private Investments, LLC | 2.1% | ||
| Differentiated Ventures Investments, LLC | 2.1% | ||
| 72 Investment Holdings, LLC | 2.1% | ||
| Steven A. Cohen | 3.7% | ||
|
Sirenia Capital Management LP
13G
|
7.9% |
5/15/2026
Event 3/31/2026
|
|
| Sirenia Capital Management LP | 7.9% | ||
| Alex Silverstein | 7.9% | ||
|
Vestal Point Capital, LP
13G/A
Amendment 1
|
6.5% |
5/15/2026
Event 3/31/2026
|
|
| Vestal Point Capital, LP | 6.5% | ||
| Ryan Wilder | 6.5% | ||
|
Armistice Capital, LLC
13G/A
Amendment 3
|
4.9% |
2/18/2026
Event 12/31/2025
|
|
| Armistice Capital, LLC | 4.9% | ||
| Steven Boyd | 4.9% | ||
|
Commodore Capital LP
13G/A
Amendment 1
|
9.9% |
2/17/2026
Event 12/31/2025
|
|
| Commodore Capital LP | 9.9% | ||
| Commodore Capital Master LP | 9.9% | ||
| Robert Egen Atkinson | 9.9% | ||
| Michael Kramarz | 9.9% | ||
|
Perceptive Advisors LLC
13G/A
Amendment 1
|
10.0% |
2/17/2026
Event 12/31/2025
|
|
| Perceptive Advisors LLC | 10.0% | ||
| Joseph Edelman | 10.0% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 10.0% | ||
|
K2 HealthVentures Equity Trust LLC
13G/A
Amendment 1
|
2.4% |
2/17/2026
Event 12/31/2025
|
|
| K2 HealthVentures Equity Trust LLC | 2.4% | ||
| Parag Shah | 2.4% | ||
| Anup Arora | 2.4% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 3
|
8.9% |
2/17/2026
Event 12/31/2025
|
|
| Point72 Asset Management, L.P. | 6.8% | ||
| Point72 Capital Advisors, Inc. | 6.8% | ||
| Point72 Biotech Private Investments, LLC | 2.1% | ||
| Differentiated Ventures Investments, LLC | 2.1% | ||
| 72 Investment Holdings, LLC | 2.1% | ||
| Steven A. Cohen | 8.9% | ||
|
Vestal Point Capital, LP
13G
|
8.0% |
2/17/2026
Event 12/31/2025
|
|
| Vestal Point Capital, LP | 8.0% | ||
| Ryan Wilder | 8.0% | ||
|
Commodore Capital LP
13G
|
9.8% |
10/27/2025
Event 10/20/2025
|
|
| Commodore Capital LP | 9.8% | ||
| Commodore Capital Master LP | 9.8% | ||
| Robert Egen Atkinson | 9.8% | ||
| Michael Kramarz | 9.8% | ||
|
Perceptive Advisors LLC
13G
|
7.3% |
10/10/2025
Event 10/3/2025
|
|
| Perceptive Advisors LLC | 7.3% | ||
| Joseph Edelman | 7.3% | ||
| Perceptive Life Sciences Master Fund, Ltd. | 7.3% | ||
|
Armistice Capital, LLC
13G/A
Amendment 2
|
7.1% |
8/14/2025
Event 6/30/2025
|
|
| Armistice Capital, LLC | 7.1% | ||
| Steven Boyd | 7.1% | ||
| BlackRock, Inc. 13G/A Amendment 1 | 2.1% |
7/16/2025
Event 6/30/2025
|
|
|
Armistice Capital, LLC
13G
|
5.9% |
5/15/2025
Event 3/31/2025
|
|
| Armistice Capital, LLC | 5.9% | ||
| Steven Boyd | 5.9% | ||
|
K2 HealthVentures Equity Trust LLC
13G
|
5.6% |
5/15/2025
Event 1/13/2025
|
|
| K2 HealthVentures Equity Trust LLC | 5.6% | ||
| Parag Shah | 5.6% | ||
| Anup Arora | 5.6% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 2
|
7.0% |
5/15/2025
Event 3/31/2025
|
|
| Point72 Asset Management, L.P. | 4.6% | ||
| Point72 Capital Advisors, Inc. | 4.6% | ||
| Point72 Biotech Private Investments, LLC | 2.5% | ||
| Differentiated Ventures Investments, LLC | 2.5% | ||
| 72 Investment Holdings, LLC | 2.5% | ||
| Steven A. Cohen | 7.0% | ||
|
RA Capital Management, L.P.
13G/A
Amendment 2
|
0% |
2/14/2025
Event 12/31/2024
|
|
| RA Capital Management, L.P. | 0% | ||
| Peter Kolchinsky | 0% | ||
| Rajeev Shah | 0% | ||
| RA Capital Healthcare Fund, L.P. | 0% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 1
|
8.8% |
2/14/2025
Event 12/31/2024
|
|
| Point72 Asset Management, L.P. | 6.3% | ||
| Point72 Capital Advisors, Inc. | 6.3% | ||
| Point72 Biotech Private Investments, LLC | 2.5% | ||
| Differentiated Ventures Investments, LLC | 2.5% | ||
| 72 Investment Holdings, LLC | 2.5% | ||
| Steven A. Cohen | 8.8% | ||
|
FMR LLC
13G/A
Amendment 1
|
4.7% |
2/12/2025
Event 12/31/2024
|
|
| FMR LLC | 4.7% | ||
| Abigail P. Johnson | 4.7% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 4 | 12.2 k | $313 k |
| 2026 Q2 | 120 | 29.5 M | $778 M |
| 2026 Q1 | 114 | 26.8 M | $602 M |
| 2025 Q4 | 100 | 24.5 M | $436 M |
| 2025 Q3 | 79 | 17.0 M | $68.2 M |
| 2025 Q2 | 83 | 17.3 M | $38.1 M |
| 2025 Q1 | 87 | 20.8 M | $45.0 M |
| 2024 Q4 | 82 | 22.5 M | $95.3 M |
| 2024 Q3 | 88 | 23.0 M | $266 M |
| 2024 Q2 | 62 | 18.7 M | $199 M |
| 2024 Q1 | 58 | 16.0 M | $246 M |