| Quarter | Holdings | Value ($000) | Top Holdings | Form Type | Date Filed | Filing ID |
|---|---|---|---|---|---|---|
| Q4 2024 | 26 | 850,096 | NAMS, NUVL, PHVS, IRON | 13F-HR | 2/14/2025 | 000095012325002317 |
| Q3 2024 | 24 | 961,175 | NUVL, NAMS, IRON, DNTH | 13F-HR | 11/14/2024 | 000095012324011417 |
| Q2 2024 | 25 | 910,841 | NUVL, NAMS, IRON, DNTH | 13F-HR | 8/12/2024 | 000095012324007830 |
| Q1 2024 | 26 | 1,244,287 | NAMS, NUVL, DNTH, IRON | 13F-HR | 5/15/2024 | 000095012324005471 |
| Q4 2023 | 27 | 1,043,257 | NUVL, NAMS, PHVS, IRON | 13F-HR | 2/13/2024 | 000095012324001898 |
| Q3 2023 | 31 | 894,220 | NUVL, PHVS, NAMS, SWTX | 13F-HR | 11/14/2023 | 000095012323010856 |
| Q2 2023 | 32 | 970,993 | NUVL, NAMS, SWTX, PHVS | 13F-HR | 8/14/2023 | 000095012323008184 |
| Q1 2023 | 34 | 800,117 | NAMS, NUVL, SWTX, IRON | 13F-HR | 5/15/2023 | 000095012323005321 |
| Q4 2022 | 33 | 894,849 | SWTX, NUVL, NAMS, NTRA | 13F-HR | 2/14/2023 | 000095012323002178 |
| Q3 2022 | 33 | 837,757 | SWTX, NUVL, MRSN, ARQT | 13F-HR | 11/14/2022 | 000095012322012270 |
| Q2 2022 | 35 | 852,695 | SWTX, DVAX, PHVS, ARQT | 13F-HR | 8/15/2022 | 000095012322009430 |
| Q1 2022 | 34 | 1,029,621 | SWTX, DVAX, ARQT, PHVS | 13F-HR | 5/16/2022 | 000095012322006412 |
| Q4 2021 | 34 | 1,260,974 | SWTX, DVAX, RPID, ARQT | 13F-HR | 2/14/2022 | 000095012322002471 |
| Q3 2021 | 33 | 1,612,006 | SWTX, DVAX, RPID, AVIR | 13F-HR | 11/15/2021 | 000095012321015534 |
| Q2 2021 | 30 | 1,526,199 | SWTX, AVIR, DVAX, DRNA | 13F-HR | 8/16/2021 | 000095012321011522 |
| Q1 2021 | 31 | 1,765,308 | SWTX, AVIR, ARQT, DVAX | 13F-HR | 5/17/2021 | 000095012321006704 |
| Q4 2020 | 26 | 1,592,801 | SWTX, AVIR, ARQT, MRSN | 13F-HR | 2/16/2021 | 000095012321002146 |
| Q3 2020 | 22 | 1,072,931 | SWTX, ARQT, ANNX, DRNA | 13F-HR | 11/16/2020 | 000095012320011923 |
| Q2 2020 | 15 | 954,774 | SWTX, ARQT, DRNA, DVAX | 13F-HR | 8/14/2020 | 000095012320008777 |
| Q1 2020 | 11 | 591,296 | SWTX, ARQT, DRNA, CNST | 13F-HR | 5/15/2020 | 000095012320005061 |
| Q4 2019 | 10 | 670,536 | SWTX, CNST, DRNA, DVAX | 13F-HR | 2/14/2020 | 000095012320002136 |
| Q3 2019 | 7 | 388,402 | SWTX, DRNA, SLDB, REPL | 13F-HR | 11/14/2019 | 000095012319011059 |
| Q2 2019 | 5 | 196,868 | DRNA, REPL, MRNS, SLDB | 13F-HR | 8/14/2019 | 000095012319007984 |
| Q1 2019 | 6 | 250,119 | DRNA, REPL, IFRX, MRNS | 13F-HR | 5/15/2019 | 000095012319005099 |
| Q4 2018 | 6 | 292,636 | DRNA, IFRX, SLDB, APTX | 13F-HR | 2/14/2019 | 000095012319001853 |
| Q3 2018 | 6 | 440,629 | DRNA, SLDB, APTX, IFRX | 13F-HR | 11/14/2018 | 000095012318011520 |
| Q2 2018 | 5 | 319,135 | DRNA, SLDB, IFRX, APTX | 13F-HR | 8/14/2018 | 000095012318008490 |
| Q1 2018 | 4 | 169,604 | DRNA, IFRX, MRNS, SLDB | 13F-HR | 5/15/2018 | 000095012318005392 |
| Q4 2017 | 3 | 152,407 | DRNA, IFRX, MRNS | 13F-HR | 2/14/2018 | 000095012318001950 |