| Quarter | Holdings | Value ($000) | Top Holdings | Form Type | Date Filed | Filing ID |
|---|---|---|---|---|---|---|
| Q3 2023 | 1 | 29,226 | TXG | 13F-HR | 11/13/2023 | 000110465923117289 |
| Q2 2023 | 1 | 39,564 | TXG | 13F-HR | 8/11/2023 | 000110465923090053 |
| Q1 2023 | 1 | 39,528 | TXG | 13F-HR | 5/12/2023 | 000110465923059496 |
| Q4 2022 | 1 | 49,504 | TXG | 13F-HR | 2/13/2023 | 000110465923019771 |
| Q3 2022 | 1 | 49,940 | TXG | 13F-HR | 11/14/2022 | 000110465922117990 |
| Q2 2022 | 1 | 79,347 | TXG | 13F-HR | 8/12/2022 | 000110465922089756 |
| Q1 2022 | 1 | 133,391 | TXG | 13F-HR | 5/13/2022 | 000110465922059930 |
| Q4 2021 | 2 | 262,931 | TXG, EPZM | 13F-HR | 2/11/2022 | 000110465922020348 |
| Q3 2021 | 4 | 281,405 | TXG, NVAX, XLRN, EPZM | 13F-HR | 11/12/2021 | 000110465921137696 |
| Q2 2021 | 4 | 371,748 | TXG, NVAX, EPZM, XLRN | 13F-HR | 8/16/2021 | 000110465921105285 |
| Q1 2021 | 4 | 435,036 | TXG, NVAX, EPZM, XLRN | 13F-HR | 5/17/2021 | 000110465921067101 |
| Q4 2020 | 4 | 378,743 | TXG, EPZM, NVAX, XLRN | 13F-HR | 2/16/2021 | 000110465921023076 |
| Q3 2020 | 4 | 459,571 | TXG, EPZM, NVAX, XLRN | 13F-HR | 11/13/2020 | 000110465920124779 |
| Q2 2020 | 3 | 508,684 | TXG, EPZM, XLRN | 13F-HR | 8/13/2020 | 000110465920094439 |
| Q1 2020 | 6 | 428,291 | TXG, EPZM, INSM, AERI | 13F-HR | 5/14/2020 | 000110465920061243 |
| Q4 2019 | 5 | 607,331 | TXG, AERI, INSM, EPZM | 13F-HR | 2/5/2020 | 000110465920010864 |
| Q3 2019 | 7 | 473,022 | TXG, AIMT, AERI, INSM | 13F-HR | 11/13/2019 | 000110465919062958 |
| Q2 2019 | 7 | 177,867 | AIMT, AERI, INSM, EPZM | 13F-HR | 8/13/2019 | 000114420419039327 |
| Q1 2019 | 8 | 221,488 | AERI, AIMT, INSM, ALDR | 13F-HR | 5/14/2019 | 000114420419025829 |
| Q4 2018 | 10 | 188,692 | AIMT, AERI, ALDR, INSM | 13F-HR | 2/13/2019 | 000114420419007300 |
| Q3 2018 | 10 | 270,204 | AERI, AIMT, ALDR, INSM | 13F-HR | 11/13/2018 | 000114420418059266 |
| Q2 2018 | 10 | 283,859 | AERI, AIMT, ALDR, INSM | 13F-HR | 8/14/2018 | 000114420418044623 |
| Q1 2018 | 11 | 300,625 | AIMT, AERI, EPZM, INSM | 13F-HR | 5/15/2018 | 000114420418028462 |
| Q4 2017 | 11 | 286,236 | AIMT, AERI, EPZM, INSM | 13F-HR | 2/13/2018 | 000114420418007688 |
| Q3 2017 | 12 | 246,705 | AIMT, AERI, EPZM, ALDR | 13F-HR | 11/13/2017 | 000114420417058212 |
| Q2 2017 | 13 | 218,256 | AERI, AIMT, EPZM, ALDR | 13F-HR | 8/14/2017 | 000114420417042938 |
| Q1 2017 | 13 | 233,108 | AIMT, AERI, EPZM, ALDR | 13F-HR | 5/12/2017 | 000114420417026668 |
| Q4 2016 | 9 | 199,266 | AIMT, AERI, ALDR, EPZM | 13F-HR | 2/10/2017 | 000114420417007450 |
| Q3 2016 | 10 | 209,419 | AERI, AIMT, ALDR, UAM | 13F-HR | 11/14/2016 | 000114420416133782 |
| Q2 2016 | 15 | 146,280 | AIMT, UAM, AERI, ALDR | 13F-HR | 8/12/2016 | 000114420416118725 |
| Q1 2016 | 20 | 204,330 | AIMT, UAM, ADRO, EPZM | 13F-HR | 5/6/2016 | 000114420416099539 |
| Q4 2015 | 24 | 298,243 | AIMT, ADRO, ADAPY, UAM | 13F-HR | 2/12/2016 | 000114420416081039 |
| Q3 2015 | 29 | 329,345 | AIMT, ADRO, ZFGN, ADAPY | 13F-HR | 11/13/2015 | 000114420415065115 |
| Q2 2015 | 22 | 284,975 | ADRO, ADAPY, UAM, ZFGN | 13F-HR | 8/14/2015 | 000114420415049188 |
| Q1 2015 | 17 | 168,778 | ZFGN, OREX, EPZM, ASPX | 13F-HR | 5/5/2015 | 000114420415027507 |
| Q4 2014 | 23 | 146,039 | UAM, OREX, ZFGN, ASPX | 13F-HR | 2/11/2015 | 000114420415008023 |