| Quarter | Holdings | Value ($000) | Top Holdings | Form Type | Date Filed | Filing ID |
|---|---|---|---|---|---|---|
| Q3 2022 | 1 | 21,360 | TXG | 13F-HR | 11/14/2022 | 000110465922117989 |
| Q2 2022 | 1 | 33,938 | TXG | 13F-HR | 8/12/2022 | 000110465922089753 |
| Q1 2022 | 2 | 57,218 | TXG, EPZM | 13F-HR | 5/13/2022 | 000110465922059927 |
| Q4 2021 | 2 | 112,079 | TXG, EPZM | 13F-HR | 2/11/2022 | 000110465922020346 |
| Q3 2021 | 4 | 127,826 | TXG, NVAX, XLRN, EPZM | 13F-HR | 11/12/2021 | 000110465921137694 |
| Q2 2021 | 4 | 165,887 | TXG, NVAX, EPZM, XLRN | 13F-HR | 8/16/2021 | 000110465921105284 |
| Q1 2021 | 4 | 198,262 | TXG, NVAX, XLRN, EPZM | 13F-HR | 5/17/2021 | 000110465921067097 |
| Q4 2020 | 4 | 190,084 | TXG, NVAX, EPZM, XLRN | 13F-HR | 2/16/2021 | 000110465921023071 |
| Q3 2020 | 4 | 355,166 | TXG, NVAX, EPZM, XLRN | 13F-HR | 11/13/2020 | 000110465920124777 |
| Q2 2020 | 3 | 317,262 | TXG, EPZM, XLRN | 13F-HR | 8/13/2020 | 000110465920094438 |
| Q1 2020 | 2 | 361,447 | TXG, XLRN | 13F-HR | 5/14/2020 | 000110465920061240 |
| Q4 2019 | 2 | 552,123 | TXG, XLRN | 13F-HR | 2/5/2020 | 000110465920010866 |
| Q3 2015 | 3 | 9,379 | XLRN, BDSI, OREX | 13F-HR | 11/13/2015 | 000114420415065110 |
| Q2 2015 | 3 | 15,149 | OREX, XLRN, BDSI | 13F-HR | 8/14/2015 | 000114420415049190 |
| Q1 2015 | 4 | 21,737 | OREX, BDSI, XLRN, RXDX | 13F-HR | 5/5/2015 | 000114420415027505 |
| Q4 2014 | 6 | 67,901 | KPTI, XNCR, BDSI, OREX | 13F-HR | 2/11/2015 | 000114420415008028 |
| Q3 2014 | 8 | 104,426 | KPTI, AMBI, BDSI, XNCR | 13F-HR | 11/10/2014 | 000114420414066347 |
| Q2 2014 | 8 | 119,290 | KPTI, AMBI, XNCR, ACRX | 13F-HR | 8/11/2014 | 000114420414048394 |
| Q1 2014 | 11 | 142,352 | KPTI, KERX, AMBI, ACRX | 13F-HR | 5/15/2014 | 000114420414030644 |
| Q4 2013 | 9 | 102,940 | KPTI, AMBI, KERX, ACRX | 13F-HR | 2/14/2014 | 000114420414009003 |