| Quarter | Holdings | Value ($000) | Top Holdings | Form Type | Date Filed | Filing ID |
|---|---|---|---|---|---|---|
| Q2 2026 | 8 | 162,612 | GLUE, IPSC, JBIO, LENZ | 13F-HR | 8/12/2026 | 000119312526347068 |
| Q1 2026 | 8 | 141,410 | GLUE, IPSC, LENZ, JBIO | 13F-HR | 5/5/2026 | 000119312526206555 |
| Q4 2025 | 7 | 151,060 | GLUE, LENZ, JBIO, CRSP | 13F-HR | 2/12/2026 | 000119312526048719 |
| Q3 2025 | 9 | 212,452 | LENZ, GLUE, Jade Biosciences, Inc., CRSP | 13F-HR | 11/10/2025 | 000119312525274459 |
| Q2 2025 | 8 | 82,136 | GLUE, CRSP, Jade Biosciences, Inc., SKYE | 13F-HR | 8/11/2025 | 000095012325007471 |
| Q1 2025 | 7 | 60,208 | GLUE, CRSP, CTNM, SKYE | 13F-HR | 5/7/2025 | 000095012325004223 |
| Q4 2024 | 7 | 86,748 | GLUE, CRSP, CTNM, SKYE | 13F-HR | 2/11/2025 | 000095012325001612 |
| Q3 2024 | 6 | 63,573 | CRSP, CTNM, RPTX, SKYE | 13F-HR | 11/8/2024 | 000095012324010733 |
| Q2 2024 | 8 | 77,296 | CRSP, CTNM, SKYE, RPTX | 13F-HR | 8/7/2024 | 000095012324007328 |
| Q1 2024 | 7 | 103,136 | CRSP, SKYE, RPTX, GRTSQ | 13F-HR | 5/3/2024 | 000095012324003797 |
| Q4 2023 | 7 | 388,843 | RYZB, CRSP, RPTX, GRTSQ | 13F-HR | 2/8/2024 | 000095012324001156 |
| Q3 2023 | 8 | 188,112 | RYZB, RPTX, CRSP, ADVM | 13F-HR | 11/3/2023 | 000095012323009395 |
| Q2 2023 | 8 | 84,298 | RPTX, CRSP, ADVM, GRTSQ | 13F-HR | 8/9/2023 | 000095012323007098 |
| Q1 2023 | 7 | 47,972 | CRSP, GRTSQ, PASG, CBAY | 13F-HR | 5/10/2023 | 000095012323004367 |
| Q4 2022 | 7 | 48,328 | CRSP, GRTSQ, PASG, CBAY | 13F-HR | 2/9/2023 | 000095012323001275 |
| Q3 2022 | 8 | 58,655 | CRSP, GRTSQ, PASG, ADVM | 13F-HR | 11/10/2022 | 000095012322011472 |
| Q2 2022 | 8 | 65,230 | CRSP, PASG, GRTSQ, ADVM | 13F-HR | 8/11/2022 | 000095012322008452 |
| Q1 2022 | 10 | 100,171 | CRSP, PASG, GRTSQ, CRNX | 13F-HR | 5/10/2022 | 000095012322005030 |
| Q4 2021 | 10 | 186,975 | GRTSQ, CRSP, PASG, ALGS | 13F-HR | 2/11/2022 | 000095012322001851 |
| Q3 2021 | 11 | 241,512 | CRSP, PASG, GRTSQ, ALGS | 13F-HR | 11/12/2021 | 000095012321014984 |
| Q2 2021 | 11 | 301,807 | CRSP, PASG, ALGS, GRTSQ | 13F-HR | 8/12/2021 | 000095012321010561 |
| Q1 2021 | 11 | 513,262 | CRSP, PASG, ALGS, ADVM | 13F-HR | 5/6/2021 | 000095012321005457 |
| Q4 2020 | 12 | 962,968 | CRSP, NARI, ALGS, ADVM | 13F-HR | 2/16/2021 | 000095012321002373 |
| Q3 2020 | 11 | 546,369 | CRSP, ADVM, APRE, FLXN | 13F-HR | 11/12/2020 | 000095012320011532 |
| Q2 2020 | 12 | 696,065 | CRSP, ADVM, APRE, AKRO | 13F-HR | 7/20/2020 | 000110465920084768 |
| Q1 2020 | 9 | 364,636 | CRSP, ADVM, AKRO, VCYT | 13F-HR | 4/28/2020 | 000110465920052226 |
| Q4 2019 | 7 | 331,845 | CRSP, VCYT, GRTSQ, OCUL | 13F-HR | 1/21/2020 | 000110465920005491 |
| Q3 2019 | 8 | 258,454 | CRSP, VCYT, GRTSQ, BOLD | 13F-HR | 10/8/2019 | 000110465919053357 |
| Q2 2019 | 9 | 343,186 | CRSP, VCYT, GRTSQ, BOLD | 13F-HR | 7/12/2019 | 000110465919039996 |
| Q1 2019 | 9 | 303,568 | CRSP, VCYT, BOLD, CBAY | 13F-HR | 4/5/2019 | 000110465919020144 |
| Q4 2018 | 10 | 202,020 | CRSP, VCYT, BOLD, OCUL | 13F-HR | 1/22/2019 | 000110465919002754 |
| Q3 2018 | 10 | 294,005 | CRSP, BOLD, VCYT, OCUL | 13F-HR | 10/5/2018 | 000110465918060749 |
| Q2 2018 | 9 | 320,525 | CRSP, BOLD, OCUL, CBAY | 13F-HR | 7/13/2018 | 000110465918045045 |
| Q1 2018 | 8 | 312,675 | CRSP, BOLD, AKAOQ, OCUL | 13F-HR | 5/3/2018 | 000110465918030300 |
| Q4 2017 | 7 | 95,029 | BOLD, AKAOQ, OCUL, CBAY | 13F-HR | 1/25/2018 | 000110465918003973 |
| Q3 2017 | 8 | 131,378 | BOLD, IMDZ, AKAOQ, OCUL | 13F-HR | 10/13/2017 | 000110465917062084 |
| Q2 2017 | 8 | 127,127 | BOLD, AKAOQ, IMDZ, OCUL | 13F-HR | 8/2/2017 | 000110465917048730 |
| Q1 2017 | 8 | 137,509 | AKAOQ, BOLD, CLVSQ, OCUL | 13F-HR | 4/7/2017 | 000110465917022191 |
| Q4 2016 | 7 | 102,740 | BOLD, OCUL, CLVSQ, AKAOQ | 13F-HR | 1/18/2017 | 000110465917002761 |
| Q3 2016 | 7 | 89,691 | BOLD, IMDZ, OCUL, CLVSQ | 13F-HR | 10/24/2016 | 000110465916151423 |
| Q2 2016 | 5 | 98,672 | GKOS, OCUL, CLVSQ, AKAOQ | 13F-HR | 7/28/2016 | 000110465916135018 |
| Q1 2016 | 7 | 138,515 | GKOS, FPRX, OCUL, CLVSQ | 13F-HR | 4/25/2016 | 000110465916113751 |
| Q4 2015 | 7 | 170,904 | GKOS, FPRX, OCUL, CLVSQ | RESTATEMENT | 5/5/2016 | 000110465916118185 |
| Q3 2015 | 7 | 174,363 | GKOS, CLVSQ, OCUL, FPRX | 13F-HR | 10/28/2015 | 000110465915073439 |
| Q2 2015 | 5 | 78,844 | CLVSQ, FPRX, AKAOQ, BITI | 13F-HR | 7/15/2015 | 000110465915051249 |
| Q1 2015 | 6 | 113,697 | CLVSQ, FPRX, AKAOQ, CBAY | 13F-HR | 4/23/2015 | 000110465915029755 |
| Q4 2014 | 5 | 104,586 | CLVSQ, FPRX, AKAOQ, CBAY | RESTATEMENT | 4/23/2015 | 000110465915029709 |