| Quarter | Holdings | Value ($000) | Top Holdings | Form Type | Date Filed | Filing ID |
|---|---|---|---|---|---|---|
| Q4 2024 | 5 | 334,222 | MRNA, FHTX, SANA, OMGA | 13F-HR | 2/14/2025 | 000095012325002708 |
| Q3 2024 | 6 | 591,878 | MRNA, FHTX, SANA, OMGA | 13F-HR | 11/14/2024 | 000095012324011756 |
| Q2 2024 | 6 | 843,359 | MRNA, SANA, FHTX, OMGA | 13F-HR | 8/14/2024 | 000095012324008727 |
| Q1 2024 | 7 | 1,524,565 | MRNA, SANA, OMGA, FHTX | 13F-HR | 5/15/2024 | 000095012324005589 |
| Q4 2023 | 7 | 1,325,311 | MRNA, SANA, OMGA, FHTX | 13F-HR | 2/14/2024 | 000095012324002510 |
| Q3 2023 | 9 | 1,377,673 | MRNA, SANA, FHTX, OMGA | 13F-HR | 11/14/2023 | 000095012323010821 |
| Q2 2023 | 10 | 2,240,750 | MRNA, SANA, OMGA, MCRB | 13F-HR | 8/14/2023 | 000095012323008070 |
| Q1 2023 | 11 | 2,573,424 | MRNA, OMGA, MCRB, SANA | 13F-HR | 5/15/2023 | 000095012323005258 |
| Q4 2022 | 12 | 3,132,284 | MRNA, OMGA, SANA, MCRB | 13F-HR | 2/14/2023 | 000095012323002460 |
| Q3 2022 | 12 | 2,375,805 | MRNA, SANA, MCRB, OMGA | 13F-HR | 11/14/2022 | 000095012322012261 |
| Q2 2022 | 12 | 2,654,624 | MRNA, SANA, FHTX, EVLO | 13F-HR | 8/15/2022 | 000095012322009421 |
| Q1 2022 | 13 | 4,258,761 | MRNA, SANA, RUBY, FHTX | 13F-HR | 5/16/2022 | 000095012322006309 |
| Q4 2021 | 13 | 6,467,997 | MRNA, SANA, RUBY, OMGA | 13F-HR | 2/14/2022 | 000095012322002901 |
| Q3 2021 | 13 | 9,549,130 | MRNA, SANA, RUBY, OMGA | 13F-HR | 11/15/2021 | 000095012321015487 |
| Q2 2021 | 12 | 7,829,539 | MRNA, RUBY, SANA, MCRB | 13F-HR | 8/16/2021 | 000095012321011113 |
| Q1 2021 | 12 | 6,244,355 | MRNA, SANA, RUBY, MCRB | 13F-HR | 5/17/2021 | 000095012321007079 |
| Q4 2020 | 11 | 5,493,282 | MRNA, SGTX, MCRB, RUBY | 13F-HR | 2/16/2021 | 000095012321002948 |
| Q3 2020 | 8 | 3,619,952 | MRNA, MCRB, KLDO, DNLI | 13F-HR | 11/16/2020 | 000095012320012128 |
| Q2 2020 | 8 | 3,441,586 | MRNA, RUBY, DNLI, KLDO | 13F-HR | 8/13/2020 | 000095012320008652 |
| Q1 2020 | 8 | 2,133,438 | MRNA, RUBY, DNLI, KLDO | 13F-HR | 5/14/2020 | 000095012320004927 |
| Q4 2019 | 9 | 1,788,867 | MRNA, RUBY, DNLI, KLDO | 13F-HR | 2/13/2020 | 000095012320001884 |
| Q3 2019 | 10 | 1,828,054 | MRNA, RUBY, KLDO, DNLI | 13F-HR | 11/14/2019 | 000095012319011393 |
| Q2 2019 | 10 | 2,310,279 | MRNA, RUBY, KLDO, DNLI | 13F-HR | 8/13/2019 | 000095012319007818 |
| Q1 2019 | 8 | 2,642,256 | MRNA, RUBY, KLDO, DNLI | 13F-HR | 5/14/2019 | 000101297519000346 |
| Q4 2018 | 7 | 2,047,628 | MRNA, RUBY, EVLO, DNLI | 13F-HR | 2/13/2019 | 000101297519000145 |
| Q3 2018 | 6 | 1,513,015 | RUBY, EVLO, DNLI, MCRB | 13F-HR | 11/13/2018 | 000101297518001201 |
| Q2 2018 | 5 | 522,113 | EVLO, DNLI, MCRB, SYRS | 13F-HR | 8/7/2018 | 000101297518000952 |
| Q1 2018 | 4 | 344,896 | DNLI, MCRB, SYRS, QTRX | 13F-HR | 5/15/2018 | 000101297518000415 |
| Q4 2017 | 5 | 394,322 | DNLI, MCRB, EDIT, QTRX | 13F-HR | 2/14/2018 | 000101297518000160 |
| Q3 2017 | 4 | 298,998 | MCRB, SYRS, EDIT, T2 BIOSYSTEMS INC | 13F-HR | 11/3/2017 | 000101297517000806 |
| Q2 2017 | 4 | 283,568 | MCRB, SYRS, EDIT, T2 BIOSYSTEMS INC | 13F-HR | 8/2/2017 | 000101297517000578 |
| Q1 2017 | 7 | 376,254 | MCRB, SYRS, EDIT, AGIO | 13F-HR | 5/10/2017 | 000101297517000377 |
| Q4 2016 | 7 | 307,344 | MCRB, SYRS, EDIT, AGIO | 13F-HR | 2/13/2017 | 000101297517000113 |
| Q3 2016 | 7 | 365,999 | MCRB, SYRS, AGIO, EDIT | 13F-HR | 11/14/2016 | 000101297516001561 |