| Quarter | Holdings | Value ($000) | Top Holdings | Form Type | Date Filed | Filing ID |
|---|---|---|---|---|---|---|
| Q3 2024 | 6 | 145,272 | TRDA, ITOS, DYN, HOWL | 13F-HR | 11/12/2024 | 000095012324011020 |
| Q2 2024 | 6 | 182,086 | TRDA, DYN, ITOS, HOWL | 13F-HR | 8/14/2024 | 000095012324008624 |
| Q1 2024 | 6 | 245,154 | DYN, TRDA, ITOS, HOWL | 13F-HR | 5/15/2024 | 000095012324005709 |
| Q4 2023 | 7 | 203,501 | TRDA, DYN, ITOS, HOWL | 13F-HR | 2/13/2024 | 000095012324001862 |
| Q3 2023 | 7 | 186,705 | TRDA, DYN, ITOS, RPTX | 13F-HR | 11/14/2023 | 000095012323010947 |
| Q2 2023 | 8 | 203,918 | TRDA, DYN, ITOS, RPTX | RESTATEMENT | 9/7/2023 | 000095012323008457 |
| Q1 2023 | 9 | 239,992 | TRDA, DYN, AMYT, ITOS | 13F-HR | 5/12/2023 | 000095012323004667 |
| Q4 2022 | 9 | 239,006 | TRDA, DYN, ITOS, RPTX | 13F-HR | 2/14/2023 | 000095012323002466 |
| Q3 2022 | 9 | 262,550 | TRDA, DYN, ITOS, RPTX | 13F-HR | 11/14/2022 | 000095012322011903 |
| Q2 2022 | 10 | 236,983 | ITOS, TRDA, DYN, RPTX | 13F-HR | 8/11/2022 | 000095012322008457 |
| Q1 2022 | 10 | 292,569 | ITOS, DYN, TRDA, RPTX | 13F-HR | 5/13/2022 | 000095012322005663 |
| Q4 2021 | 10 | 462,742 | ITOS, TRDA, DYN, HOWL | 13F-HR | 2/11/2022 | 000095012322002230 |
| Q3 2021 | 9 | 431,481 | ITOS, DYN, HOWL, RPTX | 13F-HR | 11/15/2021 | 000095012321015021 |
| Q2 2021 | 9 | 537,884 | DYN, ITOS, HOWL, RPTX | 13F-HR | 8/13/2021 | 000095012321010733 |
| Q1 2021 | 8 | 517,625 | ITOS, TCRR, RPTX, DYN | 13F-HR | 5/13/2021 | 000095012321006304 |
| Q4 2020 | 8 | 706,647 | ITOS, TCRR, DYN, RPTX | 13F-HR | 2/16/2021 | 000095012321002275 |
| Q3 2020 | 8 | 536,268 | DYN, RPTX, ITOS, TCRR | 13F-HR | 11/13/2020 | 000095012320011704 |
| Q2 2020 | 6 | 336,080 | RPTX, HARP, TCRR, RYTM | 13F-HR | 8/12/2020 | 000095012320008316 |
| Q1 2020 | 5 | 164,386 | HARP, RYTM, TCRR, SNDX | 13F-HR | 5/13/2020 | 000095012320004636 |
| Q4 2019 | 5 | 227,210 | HARP, TCRR, RYTM, CHMA | 13F-HR | 2/14/2020 | 000095012320002307 |
| Q3 2019 | 5 | 233,671 | RYTM, HARP, TCRR, CHMA | 13F-HR | 11/14/2019 | 000095012319011121 |
| Q2 2019 | 5 | 247,475 | RYTM, HARP, TCRR, CHMA | 13F-HR | 8/14/2019 | 000095012319008112 |
| Q1 2019 | 7 | 242,513 | RYTM, TCRR, HARP, CHMA | RESTATEMENT | 5/29/2019 | 000095012319005747 |
| Q4 2018 | 6 | 118,173 | RYTM, CHMA, SNDX, HSTO | 13F-HR | 2/13/2019 | 000095012319001536 |
| Q3 2018 | 7 | 147,685 | RYTM, CHMA, SNDX, HSTO | 13F-HR | 11/14/2018 | 000095012318011743 |
| Q2 2018 | 9 | 258,178 | RDUS, RYTM, SNDX, HSTO | 13F-HR | 8/13/2018 | 000095012318008232 |
| Q1 2018 | 9 | 259,639 | RDUS, RYTM, SNDX, HSTO | 13F-HR | 5/11/2018 | 000095012318004893 |
| Q4 2017 | 9 | 249,517 | RDUS, RYTM, SNDX, CHMA | 13F-HR | 2/2/2018 | 000095012318000708 |
| Q3 2017 | 8 | 204,928 | RDUS, SNDX, CHMA, HSTO | 13F-HR | 11/13/2017 | 000095012317010246 |
| Q2 2017 | 9 | 230,182 | RDUS, SNDX, CHMA, HSTO | 13F-HR | 8/9/2017 | 000095012317006941 |
| Q1 2017 | 8 | 207,889 | RDUS, SNDX, CHMA, ELGXQ | 13F-HR | 5/15/2017 | 000095012317005003 |
| Q4 2016 | 8 | 211,867 | RDUS, EPZM, SNDX, CHMA | 13F-HR | 2/7/2017 | 000095012317000972 |
| Q3 2016 | 8 | 305,291 | RDUS, SNDX, EPZM, CHMA | 13F-HR | 11/10/2016 | 000095012316021719 |
| Q2 2016 | 14 | 308,298 | RDUS, SNDX, EPZM, CHMA | 13F-HR | 8/8/2016 | 000095012316018966 |
| Q1 2016 | 15 | 322,688 | RDUS, CHMA, SNDX, EPZM | 13F-HR | 5/11/2016 | 000095012316016678 |
| Q4 2015 | 15 | 560,375 | RDUS, CHMA, EPZM, TARA | 13F-HR | 2/4/2016 | 000095012316013404 |
| Q3 2015 | 16 | 650,050 | RDUS, CHMA, PTLA, EPZM | 13F-HR | 11/12/2015 | 000095012315011440 |
| Q2 2015 | 15 | 597,628 | RDUS, PTLA, EPZM, PETX | 13F-HR | 7/29/2015 | 000095012315007803 |
| Q1 2015 | 15 | 468,928 | RDUS, PTLA, EPZM, PETX | 13F-HR | 4/27/2015 | 000095012315004661 |
| Q4 2014 | 15 | 450,281 | RDUS, EPZM, PETX, PTLA | 13F-HR | 2/2/2015 | 000095012315000694 |
| Q3 2014 | 13 | 305,577 | RDUS, EPZM, PTLA, TRIV | 13F-HR | 10/23/2014 | 000095012314010421 |
| Q2 2014 | 14 | 297,255 | RDUS, EPZM, PTLA, PETX | 13F-HR | 7/17/2014 | 000095012314007200 |
| Q1 2014 | 12 | 236,264 | EPZM, PETX, MGNX, PTLA | 13F-HR | 5/8/2014 | 000095012314005089 |
| Q4 2013 | 12 | 309,628 | PETX, PTLA, EPZM, MGNX | 13F-HR | 1/23/2014 | 000095012314000466 |