| Quarter | Holdings | Value ($000) | Form Type | Date Filed | Filing ID | Name |
|---|---|---|---|---|---|---|
| Q2 2023 | 118 | 3,226,843 | 13F-HR | 8/11/2023 | 000105390623000008 | Artal Group S.A. |
| Q1 2023 | 118 | 1,682,919 | 13F-HR | 5/12/2023 | 000105390623000006 | Artal Group S.A. |
| Q4 2022 | 129 | 1,791,614 | 13F-HR | 2/13/2023 | 000105390623000002 | Artal Group S.A. |
| Q3 2022 | 135 | 2,343,188 | 13F-HR | 11/14/2022 | 000105390622000011 | Artal Group S.A. |
| Q2 2022 | 135 | 1,872,257 | 13F-HR | 8/11/2022 | 000105390622000008 | Artal Group S.A. |
| Q1 2022 | 137 | 2,388,477 | 13F-HR | 5/12/2022 | 000105390622000005 | Artal Group S.A. |
| Q4 2021 | 150 | 3,685,363 | 13F-HR | 2/11/2022 | 000105390622000002 | Artal Group S.A. |
| Q3 2021 | 146 | 4,469,381 | 13F-HR | 11/12/2021 | 000105390621000009 | Artal Group S.A. |
| Q2 2021 | 144 | 4,927,049 | 13F-HR | 8/13/2021 | 000105390621000007 | Artal Group S.A. |
| Q1 2021 | 146 | 5,659,662 | 13F-HR | 5/14/2021 | 000105390621000005 | Artal Group S.A. |
| Q4 2020 | 130 | 4,658,177 | 13F-HR | 2/11/2021 | 000105390621000002 | Artal Group S.A. |
| Q3 2020 | 134 | 4,119,259 | 13F-HR | 11/13/2020 | 000105390620000012 | Artal Group S.A. |
| Q2 2020 | 132 | 3,574,104 | 13F-HR | 8/14/2020 | 000105390620000008 | Artal Group S.A. |
| Q1 2020 | 103 | 2,366,280 | 13F-HR | 5/14/2020 | 000105390620000006 | Artal Group S.A. |
| Q4 2019 | 96 | 2,588,429 | 13F-HR | 2/13/2020 | 000105390620000004 | Artal Group S.A. |
| Q3 2019 | 102 | 2,494,140 | 13F-HR | 11/14/2019 | 000105390619000010 | Artal Group S.A. |
| Q2 2019 | 103 | 2,472,555 | 13F-HR | 8/9/2019 | 000105390619000008 | Artal Group S.A. |
| Q1 2019 | 104 | 2,448,982 | 13F-HR | 5/10/2019 | 000105390619000005 | Artal Group S.A. |
| Q4 2018 | 106 | 2,699,943 | 13F-HR | 2/11/2019 | 000105390619000003 | Artal Group S.A. |
| Q3 2018 | 106 | 3,843,825 | 13F-HR | 11/9/2018 | 000105390618000013 | Artal Group S.A. |
| Q2 2018 | 104 | 4,705,099 | 13F-HR | 8/10/2018 | 000105390618000011 | Artal Group S.A. |
| Q1 2018 | 109 | 7,991,150 | 13F-HR | 5/10/2018 | 000105390618000008 | Artal Group S.A. |
| Q4 2017 | 119 | 6,629,762 | 13F-HR | 2/9/2018 | 000105390618000005 | Artal Group S.A. |
| Q3 2017 | 111 | 5,805,179 | 13F-HR | 11/8/2017 | 000105390617000006 | Artal Group S.A. |
| Q2 2017 | 108 | 5,723,952 | 13F-HR | 8/11/2017 | 000114036117031284 | Artal Group S.A. |
| Q1 2017 | 95 | 4,505,103 | 13F-HR | 5/15/2017 | 000114036117020488 | Artal Group S.A. |
| Q4 2016 | 91 | 4,504,900 | 13F-HR | 2/14/2017 | 000114036117006297 | Artal Group S.A. |
| Q3 2016 | 92 | 5,050,578 | 13F-HR | 11/14/2016 | 000114036116086272 | Artal Group S.A. |
| Q2 2016 | 69 | 4,844,538 | 13F-HR | 8/11/2016 | 000114036116075939 | Artal Group S.A. |
| Q1 2016 | 60 | 5,126,338 | 13F-HR | 5/12/2016 | 000114036116064880 | Artal Group S.A. |
| Q4 2015 | 80 | 5,327,058 | 13F-HR | 2/12/2016 | 000114036116052358 | Artal Group S.A. |
| Q3 2015 | 76 | 4,475,776 | 13F-HR | 11/13/2015 | 000114036115041202 | Artal Group S.A. |
| Q2 2015 | 70 | 2,323,213 | 13F-HR | 8/13/2015 | 000114036115031463 | Artal Group S.A. |
| Q1 2015 | 71 | 2,163,078 | 13F-HR | 5/13/2015 | 000114036115019395 | Artal Group S.A. |
| Q4 2014 | 85 | 2,849,235 | 13F-HR | 2/13/2015 | 000114036115006101 | Artal Group S.A. |
| Q3 2014 | 86 | 2,717,198 | 13F-HR | 11/13/2014 | 000114036114041514 | Artal Group S.A. |
| Q2 2014 | 86 | 2,473,620 | 13F-HR | 8/14/2014 | 000114036114032851 | Artal Group S.A. |
| Q1 2014 | 94 | 2,762,599 | 13F-HR | 5/15/2014 | 000114036114021444 | Artal Group S.A. |
| Q4 2013 | 83 | 2,788,504 | 13F-HR | 2/14/2014 | 000114036114007106 | Artal Group S.A. |