Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 670703107 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
James E. Flynn
13G/A
Amendment 7
|
0% |
7/17/2026
Event 7/15/2026
|
|
| Deerfield Management Company, L.P. | 0% | ||
| Deerfield Mgmt IV, L.P. | 0% | ||
| Deerfield Private Design Fund IV, L.P. | 0% | ||
| Deerfield Mgmt HIF, L.P. | 0% | ||
| Deerfield Healthcare Innovations Fund, L.P. | 0% | ||
| Deerfield Mgmt, L.P. | 0% | ||
| Deerfield Partners, L.P. | 0% | ||
| James E. Flynn | 0% | ||
|
FMR LLC
13G/A
Amendment 5
|
1.9% |
7/8/2026
Event 6/30/2026
|
|
| FMR LLC | 1.9% | ||
| Abigail P. Johnson | 1.9% | ||
|
FMR LLC
13G/A
Amendment 4
|
12.6% |
5/6/2026
Event 3/31/2026
|
|
| FMR LLC | 12.6% | ||
| Abigail P. Johnson | 12.6% | ||
| Vanguard Group Inc 13G/A Amendment 2 | 0% |
3/27/2026
Event 3/13/2026
|
|
|
James E. Flynn
13G/A
Amendment 6
|
24.2% |
2/12/2026
Event 12/31/2025
|
|
| Deerfield Management Company, L.P. | 24.2% | ||
| Deerfield Mgmt IV, L.P. | 11.6% | ||
| Deerfield Private Design Fund IV, L.P. | 11.6% | ||
| Deerfield Mgmt HIF, L.P. | 11.6% | ||
| Deerfield Healthcare Innovations Fund, L.P. | 11.6% | ||
| Deerfield Mgmt, L.P. | 0.9% | ||
| Deerfield Partners, L.P. | 0.9% | ||
| James E. Flynn | 24.2% | ||
| BlackRock, Inc. 13G |
5.0%
Checked 5% or less
|
7/17/2025
Event 6/30/2025
|
|
| BlackRock, Inc. 13G/A Amendment 1 | 4.5% |
4/28/2025
Event 3/31/2025
|
|
|
James E. Flynn
13G/A
Amendment 5
|
27.6% |
2/13/2025
Event 12/31/2024
|
|
| Deerfield Management Company, L.P. | 27.6% | ||
| Deerfield Mgmt IV, L.P. | 13.2% | ||
| Deerfield Private Design Fund IV, L.P. | 13.2% | ||
| Deerfield Mgmt HIF, L.P. | 13.2% | ||
| Deerfield Healthcare Innovations Fund, L.P. | 13.2% | ||
| Deerfield Mgmt, L.P. | 1.0% | ||
| Deerfield Partners, L.P. | 1.0% | ||
| James E. Flynn | 27.6% | ||
| Vanguard Group Inc 13G/A Amendment 1 | 6.9% |
1/31/2025
Event 12/31/2024
|
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 1 | 10.0 | $1.24 k |
| 2026 Q2 | 314 | 81.7 M | $9.35 B |
| 2026 Q1 | 274 | 81.2 M | $8.30 B |
| 2025 Q4 | 247 | 80.3 M | $8.08 B |
| 2025 Q3 | 206 | 74.1 M | $6.41 B |
| 2025 Q2 | 224 | 72.1 M | $5.50 B |
| 2025 Q1 | 220 | 72.2 M | $5.12 B |
| 2024 Q4 | 236 | 70.6 M | $5.52 B |
| 2024 Q3 | 218 | 70.2 M | $7.18 B |
| 2024 Q2 | 188 | 66.4 M | $5.04 B |
| 2024 Q1 | 197 | 64.5 M | $4.84 B |
| 2023 Q4 | 180 | 64.6 M | $4.76 B |
| 2023 Q3 | 130 | 55.9 M | $2.57 B |
| 2023 Q2 | 115 | 55.3 M | $2.33 B |
| 2023 Q1 | 96 | 54.2 M | $1.41 B |
| 2022 Q4 | 105 | 53.7 M | $1.60 B |
| 2022 Q3 | 62 | 45.6 M | $887 M |
| 2022 Q2 | 56 | 45.9 M | $622 M |
| 2022 Q1 | 56 | 45.3 M | $629 M |
| 2021 Q4 | 51 | 43.8 M | $827 M |
| 2021 Q3 | 48 | 42.4 M | $941 M |