Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 528872302 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
FMR LLC
13G/A
Amendment 4
|
11.7% |
8/6/2026
Event 6/30/2026
|
|
| FMR LLC | 11.7% | ||
| Abigail P. Johnson | 11.7% | ||
|
Invus Global Management, LLC
13D/A
Amendment 26
|
39.4% |
5/8/2026
Event 4/30/2026
|
|
| Invus, L.P. | 9.6% | ||
| Invus Advisors, L.L.C. | 9.6% | ||
| Invus Public Equities, L.P. | 1.7% | ||
| Invus Public Equities Advisors, LLC | 1.7% | ||
| Invus Global Management, LLC | 9.6% | ||
| Siren, L.L.C. | 9.6% | ||
| Avicenna Life Sci Master Fund LP | 0.3% | ||
| Avicenna Life Sci Master GP LLC | 0.3% | ||
| Invus US Partners LLC | 1.2% | ||
| Ulys, L.L.C. | 1.6% | ||
| Raymond Debbane | 11.7% | ||
| Artal Participations S.a r.l. | 39.4% | ||
| Artal International S.C.A. | 39.4% | ||
| Artal International Management S.A. | 39.4% | ||
| Artal Group S.A. | 39.4% | ||
| Westend S.A. | 39.4% | ||
| Stichting Administratiekantoor Westend | 39.4% | ||
| Amaury Wittouck | 39.4% | ||
|
Invus Global Management, LLC
13D/A
Amendment 25
|
36.2% |
2/2/2026
Event 1/29/2026
|
|
| Invus, L.P. | 10.0% | ||
| Invus Advisors, L.L.C. | 10.0% | ||
| Invus Public Equities, L.P. | 1.7% | ||
| Invus Public Equities Advisors, LLC | 1.7% | ||
| Invus Global Management, LLC | 10.0% | ||
| Siren, L.L.C. | 10.0% | ||
| Avicenna Life Sci Master Fund LP | 0.4% | ||
| Avicenna Life Sci Master GP LLC | 0.4% | ||
| Invus US Partners LLC | 1.3% | ||
| Ulys, L.L.C. | 1.6% | ||
| Mr. Raymond Debbane | 12.0% | ||
| Artal Participations S.a r.l. | 36.2% | ||
| Artal International S.C.A. | 36.2% | ||
| Artal International Management S.A. | 36.2% | ||
| Artal Group S.A. | 36.2% | ||
| Westend S.A. | 36.2% | ||
| Stichting Administratiekantoor Westend | 36.2% | ||
| Mr. Amaury Wittouck | 36.2% | ||
|
FMR LLC
13G/A
Amendment 3
|
10.5% |
7/8/2025
Event 6/30/2025
|
|
| FMR LLC | 10.5% | ||
| Abigail P. Johnson | 10.5% | ||
|
FMR LLC
13G/A
Amendment 2
|
9.6% |
5/12/2025
Event 3/31/2025
|
|
| FMR LLC | 9.6% | ||
| Abigail P. Johnson | 9.6% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 13 | 306 k | $574 k |
| 2026 Q2 | 155 | 365 M | $878 M |
| 2026 Q1 | 143 | 323 M | $505 M |
| 2025 Q4 | 132 | 260 M | $299 M |
| 2025 Q3 | 134 | 255 M | $344 M |
| 2025 Q2 | 132 | 257 M | $244 M |
| 2025 Q1 | 135 | 266 M | $122 M |
| 2024 Q4 | 135 | 298 M | $220 M |
| 2024 Q3 | 144 | 289 M | $453 M |
| 2024 Q2 | 138 | 282 M | $476 M |
| 2024 Q1 | 129 | 173 M | $419 M |
| 2023 Q4 | 118 | 187 M | $286 M |
| 2023 Q3 | 119 | 189 M | $206 M |
| 2023 Q2 | 131 | 191 M | $438 M |
| 2023 Q1 | 111 | 146 M | $354 M |
| 2022 Q4 | 113 | 148 M | $283 M |
| 2022 Q3 | 106 | 149 M | $358 M |
| 2022 Q2 | 94 | 119 M | $221 M |
| 2022 Q1 | 109 | 120 M | $251 M |
| 2021 Q4 | 124 | 122 M | $480 M |
| 2021 Q3 | 105 | 121 M | $583 M |
| 2021 Q2 | 121 | 118 M | $542 M |
| 2021 Q1 | 116 | 121 M | $712 M |
| 2020 Q4 | 120 | 122 M | $418 M |
| 2020 Q3 | 100 | 104 M | $150 M |
| 2020 Q2 | 116 | 107 M | $214 M |
| 2020 Q1 | 125 | 105 M | $205 M |
| 2019 Q4 | 128 | 108 M | $448 M |
| 2019 Q3 | 117 | 103 M | $311 M |
| 2019 Q2 | 130 | 106 M | $669 M |
| 2019 Q1 | 137 | 104 M | $582 M |
| 2018 Q4 | 135 | 106 M | $703 M |
| 2018 Q3 | 138 | 108 M | $1.16 B |
| 2018 Q2 | 137 | 109 M | $1.31 B |
| 2018 Q1 | 137 | 110 M | $943 M |
| 2017 Q4 | 146 | 111 M | $1.10 B |
| 2017 Q3 | 154 | 115 M | $1.41 B |
| 2017 Q2 | 148 | 115 M | $1.89 B |
| 2017 Q1 | 150 | 114 M | $1.64 B |
| 2016 Q4 | 157 | 111 M | $1.53 B |
| 2016 Q3 | 153 | 110 M | $2.00 B |
| 2016 Q2 | 146 | 111 M | $1.59 B |
| 2016 Q1 | 136 | 111 M | $1.32 B |
| 2015 Q4 | 129 | 110 M | $1.47 B |
| 2015 Q3 | 109 | 106 M | $1.14 B |
| 2015 Q2 | 89 | 96.9 M | $780 M |