Karyopharm Therapeutics Inc.

Historical 13F Holders

Symbol
KPTI
CUSIP
48576U106
All holders as of
Q2 2026
Type
Equity
Class
COM
Reported Value, Excluding Options
Total Shares Held, Excluding Options
Total Filers

13D/G Filers

Each filer's latest filing for 48576U106 since 12/18/2024, largest first.

Filer % of Class Filed
Under 5%, checked the "5 percent or less" box, or amended by a later filing (1)
Adage Capital Management, L.P. 13G
Amended under CUSIP 48576U205 on 2/12/2026
5.2% 2/12/2025
Event 12/31/2024

13F Holders by Quarter

Period Filers Shares, Excl. Options Value, Excl. Options
2026 Q2 1 43.0 k $420 k
2026 Q1 1 84.0 k $468 k
2025 Q3 1 28.0 k $183 k
2025 Q2 1 28.0 k $121 k
2025 Q1 2 352 k $1.32 M
2024 Q4 88 61.4 M $41.5 M
2024 Q3 93 61.3 M $50.8 M
2024 Q2 118 69.5 M $60.3 M
2024 Q1 117 77.2 M $117 M
2023 Q4 124 77.3 M $66.8 M
2023 Q3 122 77.8 M $104 M
2023 Q2 140 81.5 M $145 M
2023 Q1 132 87.7 M $341 M
2022 Q4 158 107 M $363 M
2022 Q3 149 66.9 M $365 M
2022 Q2 152 67.1 M $303 M
2022 Q1 143 68.3 M $502 M
2021 Q4 147 55.0 M $353 M
2021 Q3 136 57.4 M $334 M
2021 Q2 158 59.0 M $609 M
2021 Q1 173 60.2 M $637 M
2020 Q4 172 64.4 M $997 M
2020 Q3 162 65.2 M $951 M
2020 Q2 160 69.8 M $1.32 B
2020 Q1 144 68.1 M $1.31 B
2019 Q4 153 59.8 M $1.15 B
2019 Q3 112 58.5 M $563 M
2019 Q2 107 52.0 M $312 M
2019 Q1 114 51.4 M $301 M
2018 Q4 118 52.0 M $487 M
2018 Q3 122 44.5 M $758 M
2018 Q2 110 43.7 M $742 M
2018 Q1 91 31.1 M $417 M
2017 Q4 90 31.0 M $298 M
2017 Q3 77 29.1 M $320 M
2017 Q2 74 27.8 M $251 M
2017 Q1 82 26.9 M $345 M
2016 Q4 86 25.6 M $240 M
2016 Q3 79 23.2 M $226 M
2016 Q2 75 20.0 M $135 M
2016 Q1 77 21.2 M $189 M
2015 Q4 87 21.6 M $286 M
2015 Q3 91 23.6 M $254 M
2015 Q2 90 22.5 M $611 M
2015 Q1 85 20.8 M $636 M
2014 Q4 81 18.7 M $702 M
2014 Q3 72 16.8 M $588 M
2014 Q2 79 15.3 M $712 M
2014 Q1 61 10.1 M $311 M