Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 38942Q202 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
Stonepine Capital Management, LLC
13G
|
6.0% |
8/25/2026
Event 8/19/2026
|
|
| Stonepine Capital Management, LLC | 6.0% | ||
| Stonepine Capital, L.P. | 6.0% | ||
| Stonepine GP, LLC | 6.0% | ||
| Jon M. Plexico | 6.0% | ||
|
Alafi Capital Co LLC
13D/A
Amendment 1
|
19.9% |
8/24/2026
Event 8/19/2026
|
|
| Alafi Capital Company LLC | 19.9% | ||
| Christopher D. Alafi | 19.9% | ||
|
Bering Partners II GP, L.L.C.
13D/A
Amendment 1
|
10.0% |
8/21/2026
Event 8/19/2026
|
|
| Bering Partners II GP, L.L.C. | 10.0% | ||
| Bering Partners II, L.P. | 10.0% | ||
| Evgeny Zaytsev | 10.0% | ||
| Philip M Sawyer | 10.0% | ||
|
Armistice Capital, LLC
13G
|
10.0% |
8/14/2026
Event 6/30/2026
|
|
| Armistice Capital, LLC | 10.0% | ||
| Steven Boyd | 10.0% | ||
| Woodline Partners LP 13G | 8.1% |
8/14/2026
Event 6/30/2026
|
|
|
CVI Investments, Inc.
13G
|
5.1% |
7/20/2026
Event 6/23/2026
|
|
| CVI Investments, Inc. | 5.1% | ||
| Heights Capital Management, Inc. | 5.1% | ||
|
Alafi Capital Co LLC
13D
|
17.1% |
7/10/2026
Event 6/25/2026
|
|
| Alafi Capital Company LLC | 17.1% | ||
| Christopher D. Alafi | 17.1% | ||
|
Bering Partners II GP, L.L.C.
13D
|
6.9% |
7/2/2026
Event 6/25/2026
|
|
| Bering Partners II GP, L.L.C. | 6.9% | ||
| Bering Partners II, L.P. | 6.9% | ||
| Evgeny Zaytsev | 6.9% | ||
| Philip M Sawyer | 6.9% | ||
|
Valence Investments SPV VI, LLC
13D/A
Amendment 4
|
6.4% |
6/30/2026
Event 6/25/2026
|
|
| Valence Investments SPV IV, LLC | 1.2% | ||
| Valence Investments SPV V, LLC | 0.3% | ||
| Valence Investments SPV VI, LLC | 1.0% | ||
| Eric W. Roberts | 6.4% | ||
| A. Rachel Leheny | 6.3% | ||
|
Avenue Venture Opportunities Fund II, L.P.
13G/A
Amendment 3
|
4.99% |
6/25/2026
Event 6/23/2026
|
|
| Avenue Venture Opportunities Fund II, L.P. | 4.99% | ||
| Avenue Capital Management II, L.P. | 4.99% | ||
| Avenue Venture Opportunities Partners II, LLC | 4.99% | ||
| GL Venture Opportunities Partners II, LLC | 4.99% | ||
| Marc Lasry | 4.99% | ||
| Chernett Jorey 13G/A Amendment 1 | 0% |
5/20/2026
Event 3/31/2026
|
|
|
Soleus Private Equity Fund III, L.P.
13G/A
Amendment 4
|
2.4% |
5/8/2026
Event 3/31/2026
|
|
| Soleus Private Equity Fund III, L.P. | 1.2% | ||
| Soleus Private Equity GP III, LLC | 1.2% | ||
| Soleus PE GP III, LLC | 1.2% | ||
| Soleus Capital Master Fund, L.P. | 1.2% | ||
| Soleus Capital, LLC | 1.2% | ||
| Soleus Capital Group, LLC | 1.2% | ||
| Soleus Capital Management, L.P. | 2.4% | ||
| Soleus GP, LLC | 2.4% | ||
| Guy Levy | 2.4% | ||
|
James E. Flynn
13G/A
Amendment 1
|
4.3% |
2/6/2026
Event 2/6/2026
|
|
| Deerfield Mgmt, L.P. | 4.3% | ||
| Deerfield Management Company, L.P. | 4.3% | ||
| Deerfield Partners, L.P. | 4.3% | ||
| James E. Flynn | 4.3% | ||
| Chernett Jorey 13G | 7.9% |
12/1/2025
Event 11/24/2025
|
|
|
Soleus Private Equity Fund III, L.P.
13G/A
Amendment 3
|
7.5% |
11/7/2025
Event 9/30/2025
|
|
| Soleus Private Equity Fund III, L.P. | 3.8% | ||
| Soleus Private Equity GP III, LLC | 3.8% | ||
| Soleus PE GP III, LLC | 3.8% | ||
| Soleus Capital Master Fund, L.P. | 3.8% | ||
| Soleus Capital, LLC | 3.8% | ||
| Soleus Capital Group, LLC | 3.8% | ||
| Soleus Capital Management, L.P. | 7.5% | ||
| Soleus GP, LLC | 7.5% | ||
| Guy Levy | 7.5% | ||
|
Bering Partners II GP, L.L.C.
13G
|
5.8% |
10/29/2025
Event 1/23/2024
|
|
| Bering Partners II, L.P. ("Bering II") | 5.8% | ||
| Bering Partners II GP, L.L.C. ("Bering II GP") | 5.8% | ||
| Evgeny Zaytsev ("Zaytsev") | 5.8% | ||
| Philip Sawyer ("Sawyer") | 5.8% | ||
|
Avenue Venture Opportunities Fund II, L.P.
13G/A
Amendment 2
|
8.9% |
9/9/2025
Event 9/1/2025
|
|
| Avenue Venture Opportunities Fund II, L.P. | 8.9% | ||
| Avenue Capital Management II, L.P. | 8.9% | ||
| Avenue Venture Opportunities Partners II, LLC | 8.9% | ||
| GL Venture Opportunities Partners II, LLC | 8.9% | ||
| Marc Lasry | 8.9% | ||
|
Avenue Venture Opportunities Fund II, L.P.
13G/A
Amendment 1
|
8.9% |
9/2/2025
Event 9/1/2025
|
|
| Avenue Venture Opportunities Fund II, L.P. | 8.9% | ||
| Avenue Capital Management II, L.P. | 8.9% | ||
| Avenue Venture Opportunities Partners II, LLC | 8.9% | ||
| GL Venture Opportunities Partners II, LLC | 8.9% | ||
| Marc Lasry | 8.9% | ||
|
Alafi Capital Co LLC
13G/A
Amendment 1
|
11.3% |
8/5/2025
Event 7/22/2025
|
|
| Alafi Capital Company, LLC | 11.3% | ||
| Christopher D. Alafi | 11.3% | ||
|
Avenue Venture Opportunities Fund II, L.P.
13G
|
6.7% |
5/28/2025
Event 2/28/2025
|
|
| Avenue Venture Opportunities Fund II, L.P. | 6.7% | ||
| Avenue Capital Management II, L.P. | 6.7% | ||
| Avenue Venture Opportunities Partners II, LLC | 6.7% | ||
| GL Venture Opportunities Partners II, LLC | 6.7% | ||
| Marc Lasry | 6.7% | ||
|
Stonepine Capital Management, LLC
13G/A
Amendment 1
|
4.6% |
5/14/2025
Event 3/31/2025
|
|
| Stonepine Capital Management, LLC | 4.6% | ||
| Stonepine Capital, L.P. | 4.6% | ||
| Stonepine GP, LLC | 4.6% | ||
| Jon M. Plexico | 4.6% | ||
|
Alafi Capital Co LLC
13G
|
9.6% |
4/1/2025
Event 3/25/2025
|
|
| Alafi Capital Company, LLC | 9.6% | ||
| Christopher D. Alafi | 9.6% | ||
|
Aisling Capital V, LP
13G/A
Amendment 1
|
3.9% |
3/3/2025
Event 3/3/2025
|
|
| Aisling Capital V, LP | 3.9% | ||
| Aisling Capital Partners V, LP | 3.9% | ||
| Aisling Capital Partners V LLC | 3.9% | ||
| Dr. Andrew Schiff | 3.9% | ||
| Steve Elms | 3.9% | ||
|
Revelation Healthcare Fund I, L.P.
13G/A
Amendment 1
|
0% |
2/14/2025
Event 12/31/2024
|
|
| Revelation Healthcare Fund I, L.P. | 0% | ||
| Revelation Healthcare Fund I GP, L.P. | 0% | ||
| Revelation Healthcare Fund I GP, LLC | 0% | ||
| Scott Halsted | 0% | ||
| Michael Boggs | 0% | ||
|
Stonepine Capital Management, LLC
13G
|
5.4% |
12/13/2024
Event 12/6/2024
|
|
| Stonepine Capital Management, LLC | 5.4% | ||
| Stonepine Capital, L.P. | 5.4% | ||
| Stonepine GP, LLC | 5.4% | ||
| Jon M. Plexico | 5.4% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q2 | 33 | 8.38 M | $8.45 M |
| 2026 Q1 | 28 | 1.10 M | $593 k |
| 2025 Q4 | 31 | 3.68 M | $24.2 M |
| 2025 Q3 | 31 | 3.57 M | $10.9 M |
| 2025 Q2 | 32 | 3.73 M | $5.93 M |
| 2025 Q1 | 31 | 3.97 M | $7.49 M |
| 2024 Q4 | 30 | 4.26 M | $15.1 M |
| 2024 Q3 | 26 | 3.06 M | $13.6 M |
| 2024 Q2 | 24 | 2.98 M | $11.8 M |
| 2024 Q1 | 24 | 3.55 M | $14.8 M |
| 2023 Q4 | 15 | 519 k | $1.49 M |
| 2023 Q3 | 16 | 759 k | $1.99 M |
| 2023 Q2 | 15 | 679 k | $2.72 M |