Investors who own more than 5% of a class must file a Schedule 13D or 13G. Each filer's latest filing for 221015100 since 12/18/2024, largest first.
| Filer | % of Class | Filed | ||
|---|---|---|---|---|
|
Orbimed Advisors LLC
13D/A
|
10.3% |
1/27/2026
Event 1/23/2026
|
||
| Orbimed Advisors LLC | 10.3% | |||
| Orbimed Capital GP V LLC | 10.3% | |||
|
Miller Richard A MD
13G/A
|
7.8% |
2/13/2026
Event 12/31/2025
|
||
| Richard A. Miller | 7.8% | |||
| Richard A. Miller and Sandra J. Horning, Trustees of the Miller-Horning Family Trust u/a/d January 25, 1985 | 1.6% | |||
| Sandra J. Horning | 1.6% | |||
|
Sirenia Capital Management LP
13G
|
7.5% |
5/15/2026
Event 3/31/2026
|
||
| Sirenia Capital Management LP | 7.5% | |||
| Alex Silverstein | 7.5% | |||
| BlackRock, Inc. 13G/A | 7.5% |
7/27/2026
Event 6/30/2026
|
||
| State Street Corp 13G | 5.3% |
8/7/2026
Event 6/30/2026
|
||
| Under 5%, checked the "5 percent or less" box, or amended by a later filing (4) | ||||
|
Adams Street Partners, LLC
13D/A
|
3.9% |
2/5/2026
Event 1/23/2026
|
||
| Adams Street Partners, LLC | 3.9% | |||
| Adams Street 2011 Direct Fund LP | 0.8% | |||
| Adams Street 2012 Direct Fund LP | 0.9% | |||
| Adams Street 2013 Direct Fund LP | 0.6% | |||
| Adams Street 2014 Direct Fund LP | 0.9% | |||
| Adams Street 2015 Direct Venture/Growth Fund LP | 0.1% | |||
| Adams Street 2016 Direct Venture/Growth Fund LP | 0.1% | |||
| Adams Street 2017 Direct Venture/Growth Fund LP | 0.1% | |||
| Adams Street 2018 Direct Venture/Growth Fund LP | 0.2% | |||
| Adams Street Venture/Growth Fund VI LP | 0.3% | |||
|
Point72 Asset Management, L.P.
13G/A
|
0% |
5/15/2026
Event 3/31/2026
|
||
| Point72 Asset Management, L.P. | 0% | |||
| Point72 Capital Advisors, Inc. | 0% | |||
| Steven A. Cohen | 0% | |||
|
Samlyn Capital, LLC
13G/A
|
0% |
8/14/2025
Event 6/30/2025
|
||
| Samlyn Capital, LLC | 0% | |||
| Samlyn, LP | 0% | |||
| Robert Pohly | 0% | |||
| Vanguard Group Inc 13G/A | 0% |
3/26/2026
Event 3/13/2026
|
||
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 5 | 36.1 k | $416 k |
| 2026 Q2 | 187 | 71.8 M | $1.13 B |
| 2026 Q1 | 175 | 70.1 M | $1.02 B |
| 2025 Q4 | 136 | 46.7 M | $360 M |
| 2025 Q3 | 110 | 41.7 M | $307 M |
| 2025 Q2 | 102 | 41.9 M | $168 M |
| 2025 Q1 | 106 | 36.3 M | $115 M |
| 2024 Q4 | 103 | 37.7 M | $202 M |
| 2024 Q3 | 74 | 30.1 M | $159 M |
| 2024 Q2 | 54 | 28.0 M | $50.9 M |
| 2024 Q1 | 55 | 18.5 M | $32.9 M |
| 2023 Q4 | 55 | 19.4 M | $34.2 M |
| 2023 Q3 | 57 | 19.2 M | $28.0 M |
| 2023 Q2 | 59 | 19.5 M | $44.6 M |
| 2023 Q1 | 39 | 20.8 M | $18.9 M |
| 2022 Q4 | 46 | 21.5 M | $18.3 M |
| 2022 Q3 | 50 | 22.1 M | $18.1 M |
| 2022 Q2 | 53 | 25.6 M | $25.4 M |
| 2022 Q1 | 67 | 27.4 M | $44.9 M |
| 2021 Q4 | 77 | 27.8 M | $66.9 M |
| 2021 Q3 | 77 | 28.2 M | $136 M |
| 2021 Q2 | 55 | 23.7 M | $63.2 M |
| 2021 Q1 | 53 | 20.4 M | $62.8 M |
| 2020 Q4 | 48 | 16.8 M | $59.7 M |
| 2020 Q3 | 42 | 17.2 M | $69.0 M |
| 2020 Q2 | 39 | 20.4 M | $55.6 M |
| 2020 Q1 | 45 | 20.7 M | $43.6 M |
| 2019 Q4 | 39 | 20.9 M | $114 M |
| 2019 Q3 | 36 | 22.9 M | $68.9 M |
| 2019 Q2 | 46 | 24.3 M | $91.0 M |
| 2019 Q1 | 59 | 24.8 M | $99.5 M |
| 2018 Q4 | 63 | 25.3 M | $92.7 M |
| 2018 Q3 | 65 | 25.7 M | $220 M |
| 2018 Q2 | 58 | 25.9 M | $285 M |
| 2018 Q1 | 56 | 25.4 M | $289 M |
| 2017 Q4 | 54 | 17.4 M | $180 M |
| 2017 Q3 | 54 | 17.5 M | $280 M |
| 2017 Q2 | 52 | 17.5 M | $212 M |
| 2017 Q1 | 53 | 17.3 M | $360 M |
| 2016 Q4 | 54 | 17.5 M | $250 M |
| 2016 Q3 | 45 | 16.3 M | $268 M |
| 2016 Q2 | 45 | 17.3 M | $237 M |
| 2016 Q1 | 32 | 16.4 M | $228 M |