Investors who own more than 5% of a class must file a Schedule 13D or 13G. Every filing for 00032Q104 since 12/18/2024, newest first.
| Filer | % of Class | Filed | |
|---|---|---|---|
|
ABG Management Ltd.
13G/A
Amendment 1
|
9.4% |
8/14/2026
Event 6/30/2026
|
|
| ABG Management Ltd. | 1.4% | ||
| Ally Bridge Group (NY) LLC | 1.4% | ||
| Ally Bridge MedAlpha Master Fund L.P. | 1.4% | ||
| ABG Innovation Capital Partners III GP Limited | 0% | ||
| ABG Innovation Capital Partners III GP, L.P. | 0% | ||
| Ally Bridge Group Innovation Capital Partners III, L.P. | 0% | ||
| ABG Innovation-SO Limited | 0% | ||
| ABG Global Life Science Capital Partners V GP Limited | 8.1% | ||
| ABG Global Life Science Capital Partners V GP, L.P. | 8.1% | ||
| Ally Bridge Group Global Life Science Capital Partners V, L.P. | 8.1% | ||
| Abg-Siv, L.P. | 8.1% | ||
| ABG V-SIV Limited | 8.1% | ||
| Fan Yu | 9.4% | ||
|
OrbiMed Advisors LLC
13G/A
Amendment 1
|
7.3% |
8/14/2026
Event 6/30/2026
|
|
| OrbiMed Advisors LLC | 7.3% | ||
| OrbiMed Genesis GP LLC | 7.3% | ||
|
Acuta Capital Partners, LLC
13D/A
Amendment 2
|
9.0% |
5/18/2026
Event 5/14/2026
|
|
| Acuta Capital Partners, LLC | 8.7% | ||
| Anupam Dalal | 9.0% | ||
| Acuta Capital Fund, LP | 6.6% | ||
|
Avoro Capital Advisors LLC
13D/A
Amendment 5
|
20.0% |
5/14/2026
Event 5/12/2026
|
|
| Avoro Capital Advisors LLC | 20.0% | ||
| Avoro Ventures LLC | 4.1% | ||
| Behzad Aghazadeh | 20.0% | ||
|
Coastlands Capital LP
13G
|
6.0% |
8/25/2025
Event 8/19/2025
|
|
| Coastlands Capital LP | 6.0% | ||
| Coastlands Capital Partners LP | 6.0% | ||
| Coastlands Capital GP LLC | 6.0% | ||
| Coastlands Capital LLC | 6.0% | ||
| Matthew D. Perry | 6.0% | ||
|
OrbiMed Advisors LLC
13G
|
8.9% |
5/15/2025
Event 3/31/2025
|
|
| OrbiMed Advisors LLC | 8.9% | ||
| OrbiMed Genesis GP LLC | 8.9% | ||
|
Point72 Asset Management, L.P.
13G/A
Amendment 1
|
0% |
5/15/2025
Event 3/31/2025
|
|
| Point72 Asset Management, L.P. | 0% | ||
| Point72 Capital Advisors, Inc. | 0% | ||
| Steven A. Cohen | 0% | ||
|
Suvretta Capital Management, LLC
13G
|
10.0% |
3/11/2025
Event 3/4/2025
|
|
| Suvretta Capital Management, LLC | 10.0% | ||
| Averill Master Fund, Ltd. | 8.9% | ||
| Cowen Aaron | 10.0% | ||
|
ABG Management Ltd.
13G
|
6.3% |
3/10/2025
Event 3/4/2025
|
|
| ABG Management Ltd. | 1.8% | ||
| Ally Bridge Group (NY) LLC | 1.8% | ||
| Ally Bridge MedAlpha Master Fund L.P. | 1.8% | ||
| ABG Innovation Capital Partners III GP Limited | 0.1% | ||
| ABG Innovation Capital Partners III GP, L.P. | 0.1% | ||
| Ally Bridge Group Innovation Capital Partners III, L.P. | 0.1% | ||
| ABG Innovation-SO Limited | 0.1% | ||
| ABG Global Life Science Capital Partners V GP Limited | 4.5% | ||
| ABG Global Life Science Capital Partners V GP, L.P. | 4.5% | ||
| Ally Bridge Group Global Life Science Capital Partners V, L.P. | 4.5% | ||
| Abg-Siv, L.P. | 4.5% | ||
| ABG V-SIV Limited | 4.5% | ||
| Fan Yu | 6.3% | ||
| Neil Desai 13D/A Amendment 4 | 4.9% |
3/6/2025
Event 3/4/2025
|
|
|
BML Investment Partners, L.P.
13D/A
Amendment 4
|
4.98% |
3/5/2025
Event 3/5/2025
|
|
| BML Investment Partners, L.P. | 4.3% | ||
| Leonard Braden Michael | 4.98% | ||
|
Avoro Capital Advisors LLC
13D/A
Amendment 4
|
20.0% |
3/4/2025
Event 2/28/2025
|
|
| Avoro Capital Advisors LLC | 18.0% | ||
| Avoro Ventures LLC | 4.8% | ||
| Behzad Aghazadeh | 20.0% | ||
|
BML Investment Partners, L.P.
13D/A
Amendment 3
|
9.9% |
2/24/2025
Event 2/24/2025
|
|
| BML Investment Partners, L.P. | 8.5% | ||
| Leonard Braden Michael | 9.9% | ||
| QVT Financial LP 13G | 9.4% |
2/14/2025
Event 12/31/2024
|
|
|
EcoR1 Capital, LLC
13G/A
Amendment 1
|
1.4% |
2/14/2025
Event 12/31/2024
|
|
| EcoR1 Capital, LLC | 1.4% | ||
| Oleg Nodelman | 1.4% | ||
| EcoR1 Capital Fund Qualified, L.P. | 1.3% | ||
| Satter Muneer A 13G/A Amendment 2 | 0% |
2/14/2025
Event 12/31/2024
|
|
|
BML Investment Partners, L.P.
13D/A
Amendment 2
|
9.9% |
2/4/2025
Event 2/3/2025
|
|
| BML Investment Partners, L.P. | 8.5% | ||
| Leonard Braden Michael | 9.9% | ||
|
BML Investment Partners, L.P.
13D
|
9.9% |
1/30/2025
Event 1/30/2025
|
|
| BML Investment Partners, L.P. | 8.5% | ||
| Leonard Braden Michael | 9.9% | ||
|
Point72 Asset Management, L.P.
13G
|
6.0% |
1/29/2025
Event 1/22/2025
|
|
| Point72 Asset Management, L.P. | 6.0% | ||
| Point72 Capital Advisors, Inc. | 6.0% | ||
| Steven A. Cohen | 6.0% | ||
|
Acuta Capital Partners, LLC
13D/A
Amendment 1
|
7.8% |
1/24/2025
Event 12/19/2024
|
|
| Acuta Capital Partners, LLC | 7.5% | ||
| Anupam Dalal | 7.8% | ||
| Acuta Capital Fund, LP | 6.4% | ||
|
BML Investment Partners, L.P.
13D
|
9.9% |
12/31/2024
Event 12/31/2024
|
|
| BML Investment Partners, L.P. | 8.5% | ||
| Leonard Braden Michael | 9.9% | ||
| Neil Desai 13D/A Amendment 3 | 9.2% |
12/23/2024
Event 12/19/2024
|
|
|
Avoro Capital Advisors LLC
13D/A
Amendment 3
|
14.5% |
12/23/2024
Event 12/19/2024
|
|
| Avoro Capital Advisors LLC | 11.6% | ||
| Avoro Ventures LLC | 2.5% | ||
| Behzad Aghazadeh | 14.5% |
| Period | Filings | Shares, Excl. Options | Value, Excl. Options |
|---|---|---|---|
| 2026 Q3 | 2 | 374 | $1.41 k |
| 2026 Q2 | 78 | 43.2 M | $198 M |
| 2026 Q1 | 64 | 35.2 M | $123 M |
| 2025 Q4 | 48 | 33.0 M | $79.2 M |
| 2025 Q3 | 42 | 28.8 M | $54.3 M |
| 2025 Q2 | 40 | 29.4 M | $54.6 M |
| 2025 Q1 | 53 | 31.8 M | $56.4 M |
| 2024 Q4 | 57 | 16.1 M | $50.8 M |
| 2024 Q3 | 55 | 12.0 M | $24.7 M |
| 2024 Q2 | 70 | 11.5 M | $16.8 M |
| 2024 Q1 | 66 | 14.1 M | $33.1 M |
| 2023 Q4 | 70 | 13.3 M | $26.9 M |
| 2023 Q3 | 77 | 14.7 M | $75.3 M |
| 2023 Q2 | 70 | 14.3 M | $101 M |
| 2023 Q1 | 73 | 14.3 M | $107 M |
| 2022 Q4 | 81 | 15.6 M | $196 M |
| 2022 Q3 | 71 | 15.1 M | $212 M |
| 2022 Q2 | 71 | 13.2 M | $159 M |
| 2022 Q1 | 58 | 12.8 M | $220 M |
| 2021 Q4 | 47 | 12.2 M | $295 M |
| 2021 Q3 | 33 | 11.1 M | $324 M |